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Biomedical subjects

I Betlloch

Publications and source records attributed to I Betlloch.

At least 37 records · Page 2Linked to original sources

Livedo reticularis and thrombotic purpura related to the use of diphenhydramine associated with pyrithyldione.

We describe the case of a young woman who habitually took large doses of a combination of diphenhydramine and pyrithyldione. She complained of arthralgia, painful recurring plaques and nodules, together with persistent reticular purpuric mottling and areas of necrosis on her legs. There were positive antinuclear antibodies and rheumatoid factor and histologically massive thrombosis of the dermal vessels without signs of vasculitis. Other cases of similar adverse reactions attributed to this drug combination used as a hypnotic have been described.

Adult↗

Tricoadenoma of Nikolowski.

The patient, aged 50 years, with no relevant clinical history, complained of a symptomless, soft tumor of the right buttock that had been present for many years. On examination, it was found to be pediculate, oval, somewhat erythematous, firm on palpation, and with a central keratin plug. The greatest diameter of the lesion was 1.2 cm (Fig. 1). On surgical removal of the lesion, it was seen to be composed of a symmetric intradermal proliferation of cystic formations, uniformly distributed throughout and made up of flat, pluristratified epithelium with laminated keratin. There was little difference in the thickness of the walls of the cysts (Fig. 2). Some cysts were attached to a short tadpole-shaped, epithelial cord and surrounded by a scanty fibroblastic stroma. No hairmatrix-like differentiation nor basaloid structures were seen, nor were atypical cells present. There was hardly any inflammatory infiltration.

Buttocks↗

[Gianotti-Crosti syndrome in an adult].

A 31 years old woman had an exanthematic eruption of small and acral distributed papules. At the same time she suffered a clinical and biological hepatitis B. This case is described attending to the clinic, histopathology and direct immunofluorescence. By the way the Gianotti-Crosti syndrome is reviewed.

Acrodermatitis↗

Onychopathy in a patient with fetal hydantoin syndrome.

Hydantoin is an anticonvulsant drug with several side effects. A teratogenic potential has been suggested. The fetal hydantoin syndrome is an entity that consists of a broad range of morphologic and developmental disorders in children born of epileptic mothers exposed to hydantoin during pregnancy. We treated a girl in whom onychopathy was a monosymptomatic or mild form of this syndrome.

Epilepsy↗