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Biomedical subjects

I Ben-Sira

Publications and source records attributed to I Ben-Sira.

At least 37 records · Page 2Linked to original sources
PubMed1987

'Rush' type retinopathy of prematurity: report of three cases.

Three premature infants observed to develop severe stage III retinopathy of prematurity (ROP) at 3 to 5 weeks of age received immediate treatment by cryoablation and photocoagulation, with good results. The critical importance of the ophthalmic examination of premature babies from the age of 2 weeks, so as not to overlook such cases of 'rush' type ROP is stressed and the difficulty involved in treating such small neonates is discussed.

Age Factors↗
PubMed1987

Intraocular involvement of Burkitt's lymphoma in a Bedouin child.

A child with a B-cell lymphoma with extensive abdominal disease responded to high doses of chemotherapy. One month later, eye and central nervous system recurrence developed. Intraocular involvement was documented by diagnostic vitrectomy. Differential diagnosis and therapy are discussed.

Abdominal Neoplasms↗
PubMed1987

Oxygen-induced retinopathy in newborn kittens. A model for ischemic vasoproliferative retinopathy.

Fourteen kittens were reared in 80% oxygen for 65-72 hr, after which they were returned to room air. At that time, funduscopic examination of all the kittens showed complete obliteration of the retinal vasculature and even optic disc vessels. In the following 18-21 days, florid preretinal new vessels were found growing into the vitreous from the revascularized retina and from the optic disc itself. Subsequent histologic examinations confirmed the above clinical findings and reinforced the authors to suggest this animal model as a future research tool for ischemic vasoproliferative retinopathy, rather than a model for retinopathy of prematurity (ROP). The similarities and dissimilarities between this animal model and the human ischemic retinal disease are discussed.

Animals↗
PubMed1987

Implantation growth of an iris melanocytic lesion simulating a ciliary body melanoma.

A 59-year-old woman had a sectorial pigmented iris tumor in her right eye and was found to have secondary glaucoma unresponsive to medical therapy. Gonioscopy revealed a satellite tumor in the inferior chamber angle, which we suspected to be a ciliary body melanoma. Subsequently, both lesions were removed completely by superior total and inferior partial iridocyclectomy. Histologic examination disclosed a spindle cell nevus with surface plaque associated with a borderline epithelioid cell nevus. This case is an example of unexpected clinical findings that may be encountered in any iris melanocytic lesion, benign or malignant, and the consequent problems of diagnosis and management.

Ciliary Body↗
PubMed1986

Long-term results of cryotherapy for active stages of retinopathy of prematurity.

Between 1976 and 1980, retinopathy of prematurity (ROP) stage III (moderate) (fibrovascular proliferation) developed in 29 eyes (confluent fibrovascular proliferation of 3 clock hours in extension) of 17 preterm babies. The eyes were treated by cryopexy to the avascular retina. Analysis of the visual function and anatomic results in these eyes, five to eight years postoperatively, revealed very good visual function and only a few anatomic abnormalities. Comparison of these eyes with those of two groups of age- and birth-weight-matched preterms (one with less severe ROP, not treated by cryopexy, and the other with no ROP) showed that the degree of myopia was significantly higher in the cryotreated group. Although not statistically significant, there was a higher incidence and a greater degree of astigmatism in this study group.

Cicatrix↗
PubMed1986

Unusual ophthalmological findings in a case of partial trisomy 15.

The clinical and pathological findings in a two-month old girl having partial trisomy 15, are presented. The patient showed bilateral microphthalmia accompanied by a retrolental mass in her left eye. She underwent vitrectomy, lensectomy and accidental retinectomy. During the course of the operation, persistent hyperplastic primary vitreous (PHPV) was found with findings of retinal dysplasia on the pathologic examination.

Chromosomes, Human, Pair 15↗
PubMed1985

Retinal hemorrhages in the newborn following labor induced by oxytocin or dinoprostone.

We examined the fundi of 100 newborns following labor induced by intravenous oxytocin or by oral dinoprostone. Retinal hemorrhage was observed in 40% of neonates in the dinoprostone treatment group, as compared with 28% in the oxytocin treatment group. The accumulation of prostaglandins in the fetal circulation may be responsible for the hemorrhages, which clear spontaneously once the noxious agent is metabolized. Other organ systems must be carefully examined in the neonate to detect other possible untoward effects.

Dinoprostone↗
PubMed1985

Retinopathy of prematurity: incidence and treatment.

The incidence of retinopathy of prematurity in infants with a birthweight less than or equal to 2500 g admitted to a tertiary neonatal intensive care unit between 1977 and 1983 was 20% of all survivors. There was a reciprocal relation between birthweight and the incidence of the disease, with an incidence of 68% in infants weighing less than or equal to 1000 g at birth. Cryotherapy of the avascular retina was performed if the acute disease progressed rapidly during stage 3 and the amount of fibrovascular proliferation was mild to moderate with signs of plus disease (presence of appreciable posterior pole vascular tortuosity and dilatation and the presence of engorgement of iris vessels). This method of treatment was performed in 4% of all survivors: in 26% of infants weighing less than or equal to 1000 g at birth and 5% of infants weighing 1001-1500 g. No infants had cicatricial disease greater than stage 2 on follow-up. The absence of any severe cicatricial disease or blindness in this large group of high risk infants suggests that when indicated and performed on the avascular retina cryotherapy may be an important method of treatment.

Acute Disease↗
PubMed1985

Retinal manifestations of thrombotic thrombocytopenic purpura (TTP) following use of contraceptive treatment.

An 18-year old woman, suffering from thrombotic thrombocytopenic purpura (TTP) disease after taking an oral contraceptive, developed bilateral retinal elevations in the posterior pole with Elschnig spot formation without visual acuity impairment. Clinical and laboratory evaluation combined with intensive medical and surgical therapy (splenectomy) caused regression of the ocular and general findings. We believe that the ocular pathologic findings in this clinical case are due to injury in the choroidal vasculature and the pe layer as a manifestation of the TTP disease.

Adolescent↗
PubMed1985

A clinicopathologic case of cyclectomy for malignant melanoma of the ciliary body, complicated by total traction retinal detachment.

A case report is presented of a 43-year-old woman who underwent cyclectomy for malignant melanoma of the ciliary body of the left eye. One year after operation, the eye was enucleated because of inoperable total traction retinal detachment. The pathologic examination revealed no signs of local recurrence. At five-year follow-up, no systemic spread was found.

Adult↗
PubMed1984

Retinal manifestations of acquired immunodeficiency syndrome (AIDS). Report of a case.

The syndrome of acquired immunodeficiency (AIDS) has previously been described. Originally thought to affect homosexuals and drug abusers exclusively, the disorder has also been observed in women associated with drug abuse, hemophiliacs, Haitians and, rarely, in heterosexual men. Several hundred cases have been reported in the United States whereas only a small number have been reported elsewhere. We report the first case of AIDS in Israel in a heterosexual male who developed the opportunistic infections of esophageal candidiasis and pneumocystis caranii pneumonia as well as the ischemic retinopathy which has come to be associated with the syndrome.

Acquired Immunodeficiency Syndrome↗