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Biomedical subjects

I Balslev

Publications and source records attributed to I Balslev.

At least 73 records · Page 4Linked to original sources
PubMed1980

Renal function and body composition before and after intestinal bypass operation in obese patients.

The distribution volume of [51Cr]EDTA, as an estimate of the extracellular fluid volume (ECV), glomerular filtration rate (GFR) and urinary excretion rate of endogenous creatinine (uc), as an index of muscle mass, were determined in obese patients before and after intestinal bypass operations. The results were compared to those in non-obese controls with the same age and height. GFR, ECV and uc were all significantly increased to the same extent (about 40%) in thirteen patients examined before operation (overweight 86-159%). Means of the ratio GFR/ECV and standard GFR (i.e. GFR corrected to a body surface area of 1.73 m2) did not differ from those in the controls. In eight patients examined before and 1 year after operation (body weight reduction 23-79 kg), GFR were unchanged and remained normal. ECV was significantly increased by 20% in nineteen patients investigated 1-7 years after operation (mean overweight 42%) whereas the mean of uc did not differ from that in the controls. Using the ratio GFR/ECV as reference for the function of the kidneys, the present study shows that the renal function in otherwise healthy obese subjects is normal throughout the whole range of overweight, and that standard GFR is a reliable parameter to assess the renal function even in patients with extreme obesity. The body weight reduction following intestinal bypass operation is in part due to fall in muscle mass, but the results suggest that a normal relation between body cell mass and body water is not achieved.

Adult↗
PubMed1978

Operative technique for recurrent ulcer after vagotmoy and Jaboulay gastroduodenostomy.

Seven patients with ulcer recurrence following primary operation by vagotomy and Jaboulay gastroduodenostomy were treated by methods depending on the site of recurrence. A recurrent ulcer in the stomach was treated with a broad Billroth I reconstruction. In the anterior wall of the duodenum it was necessary to excise the penetrating ulcer cutting throught the bridge to the resection edge in the first part of the duodenum. A solid longitudinal closure is practical provided that the medial collar of the second part of the duodenum is at least 1 cm from pancreas. Recurrent ulcer in the posterior duodenal wall was in one case treated by leaving a collar of the antrum after removing the mucosa. This collar was used to close the gastroduodenostomy. If a large recurrent ulcer involves the second part of the duodenum, as in three of the referred patients, it was necessary to resect not only the duodenal bulb but also the proximal extent of the second part of the duodenum. One patient developed significant postoperative complications following this procedure. We feel that the procedure itself is technically difficult and should be taken account of by all who contemplate introducing gastroduodenostomy as a routine drainage procedure.

Adult↗