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Biomedical subjects

I Balogh

Publications and source records attributed to I Balogh.

At least 73 records · Page 4Linked to original sources
PubMed1991

[Comparative peroral cholecystography and ultrasonic study of the gallbladder].

Authors--beside the admission of ultrasound examination's obvious priority--do not think that the complete cease of the gall-bladder's X-ray examination is reasonable. They have been found this on the basis of the literature and their own observations. Authors suggest the gall-bladder's examination after a negative ultrasound, if the complaints of the patient are unchanged.

Adult↗
PubMed1991

[Clinical value of body surface mapping in the diagnosis of ischemic heart disease].

A series of 137 patients suffered in clinically documented angina pectoris were analyzed by 12-lead exercise ECG, exercise body surface potential mapping and exercise thallium scintigraphic methods and the results were compared to that of selective coronary angiography and left ventriculography. If coronary artery stenosis were considered to be significant in the presence of more than 70% vessel narrowing, the sensitivity figures were 76, 93 and 88% for exercise 12-lead ECG, exercise body surface potential mapping and exercise thallium scintigraphy, respectively. In considering 50% coronary artery narrowing to be significant, the same figures were 78, 94 and 89%. Specificity figures at the same order were 59, 65 and 80% for more than 70%, and 64, 70 and 88% for more than 50% coronary obstructions. Exercise body surface potential mapping and exercise thallium scintigraphy applied parallelly gave a sensitivity of 100% and specificity of 53%. False-negative and false-positive exercise body surface potential mapping and thallium scintigraphic tests were analysed taking into consideration left ventricular function indices and respective patients. The authors suggest that the outstanding high sensitivity of the above mentioned two tests applied parallelly reveals that they highlights partially different aspects of coronary artery disease, and that is why the overlapping between the methods is relatively small. The majority of false-positive tests characterize a pathological state, and in these cases the exact diagnosis should be cleared up by other noninvasive/invasive methods.

Angina Pectoris↗
PubMed1991

Effect of nickel deficiency on biochemical variables in serum, liver, heart and kidneys of goats.

Nickel deficiency was induced in 2- to 4-year-old goats by feeding 0.1 mg Ni/kg dry matter with a semisynthetic diet. The control group consumed 5.0 mg Ni/kg d.m. Activity of several enzymes (SDH, LDH, HBDH, AST, ALT, ALD, CK, CHE) was determined in the serum, liver, heart and kidneys. Serum urea-N level was also measured and transmission electron microscopic (TEM) examinations were performed. Signs characteristic of nickel deficiency (retarded growth, increased mortality of dam and offspring, parakeratosis of the skin) appeared in the low-nickel group. The activity of SDH and ALD, as well as the level of urea-N was significantly lower in the serum of Ni-deficient animals than in the control. Ni-deficient animals also had significantly lower enzyme activities in the heart (SDH, HBDH, AST, ALT, ALD and CK), liver (SDH and CHE) and kidneys (HBDH and CK). Electron micrographs showed degeneration of cardiac and skeletal muscle in the Ni-deficient animals. Ni deficiency elicited changes primarily in the heart and these resulted in depressed activity of several enzymes.

Animals↗
PubMed1991

Cytochemical study on the local tissue effect of nickel-containing intrauterine device in rabbits.

Authors introduced a nickel-containing device into the uterus of 20 rabbits, then performed the cytochemical study of the endometrium. During calcium cytochemical study in the endometrium intramitochondrial and partly intracytoplasmic localisation while with dimethylglyoxin method intracellular reaction precipitate were found. The nickel-containing device caused local nickel and intracellular or intramitochondrial calcium accumulation.

Animals↗
PubMed1990

Comparative evaluation of the effect of balloon dilatation by exercise precordial mapping and exercise 201-thallium scintigraphy.

Precordial exercise electrocardiographic mapping and exercise 201-thallium scintigraphy were simultaneously used on sixteen patients before, shortly after and three months after percutaneous transluminal coronary angioplasty (PTCA) to evaluate the immediate and late results of the intervention. In spite of the limited number of observations, positive exercise precordial mapping and or a reversible 201-thallium perfusion defect after PTCA seem to be indicative of failure of balloon dilatation or of development of restenosis in a given coronary artery. "Reverse minimum", that is the minimum in the resting precordial map which disappears on exercise, may be a sign of segmental coronary artery occlusion and well functioning collateral supply.

Adult↗
PubMed1990

[Morphological of biological effects of progestagens].

During their clinical studies on human endometric tissue in normal and pathologic condition authors attempt to determine morphologic changes occurring to the effect of progestagens. Klt is established that progestagens cause typical morphologic changes which are manifested in regression of endometrium on varying scale. The most striking effect is exerted on mitochondria among respective cell organelles; it means the damage of these structures. Decrease of enzymatic processes linked to mitochondrea, caused by effect of progestagens, presumably inhibits cell proliferation. Inhibition of cellular oxidation in pathologic conditions, like in endometric hyperplasia and in highly differentiated cases of endometric cancer, can be of therapeutic effect. Their studies provide opportunity to interpretation of morphologic changes performed in hormone dependent tissues and to better understanding of its role in carcinogenesis of sexual hormones.

Carcinogens↗
PubMed1989

Finger receptor dysfunction in dental technicians exposed to high-frequency vibration.

The effects of high-frequency vibration (up to 40 kHz) on digital nerve function were studied in ten dental technicians and ten age-matched referents. Nerve conduction velocities, including fractionated antidromic measurements over the carpal tunnel, showed no difference between the groups. In the group of dental technicians the difference between the response latency of the mechanical and electric stimuli in the median nerve distally on the fingers of the right hand was slightly higher than in the reference group, and therefore distal nerve or receptor dysfunction was suggested. Vibration warming and cooling thresholds were significantly increased and thus revealed damage to both myelinated and unmyelinated fibers in the fingers of subjects exposed to high-frequency vibration.

Adult↗
PubMed1989

Cytochemical detection of nickel in endometrial carcinoma during progestogen treatment.

During progestogen treatment, nickel ions were detected in the human endometrial tissue of patients with endometrial carcinoma by the dimethyloxime cytochemical method. In this paper, the mechanism of action of nickel is dealt with and, because nickel ions have earlier not be detected in human endometrial carcinomatous tissues, the question arises as a result of what kind of cell biological processes, nickel ions appear in the cells of endometrial carcinoma. It is still to be answered whether the progestogen treatment applied can be correlated with the appearance of the trace element in the carcinomatous cell.

Adenocarcinoma↗
PubMed1989

New possibilities of recognizing early endometrial changes.

Ultrasonographic examinations completed by electron microscopic study were made with transvaginal head in 15 cases. According to the authors, the combined use of these two methods can improve the chances of detecting and recognizing early hyperplasia, preblastoses as well as endometrial tumours.

Adult↗
PubMed1989

Clinicopathological problems of the local tissue effect of copper-containing IUDs. II. Electron-microscopic study of the endometrial scraping.

For assessment of the tissue effect of copper-containing IUDs routine electron microscopic study was made of the endometrial scrapings. It was established that there was evidence of severe, degenerative changes not only on the IUD but also in the endometrial cells and, occasionally, also in the muscle layer of the uterus. These were characterized by pyknosis of the endometrial cells and alterations of the intracellular components. In this material of the study of 22 endometrial specimens obtained from beside IUDs, relatively few microtubuli were found in the endometrial cells. The changes seemed to be too severe to be ascribed to a sterile inflammation. The sporadic changes in the endothelial cells were found to be non-specific.

Actin Cytoskeleton↗
PubMed1989

Clinicopathological problems of the local tissue effect of IUDs containing copper. III. Cytochemical study of the endometrial scrapings.

The clinicopathological problems of the tissue effect of copper-containing IUDs are discussed. In the third part of their series, authors present the cytochemical analysis of the endometrial scrapings. For the investigations, dithizone, salicylaldoxime, rubeanic acid as well as dimethylglyoxime were used. The reaction precipitate, the copper dithizone complex, could be visualized partly intracellularly and intramitochondrially and partly interstitially. The technical problems of copper demonstration are also dealt with.

Copper↗
PubMed1989

[Histologic changes of the endometrium after Danazol treatment].

Authors have applied Danazol-treatment to 15 sexually mature patients because of beningn, menorrhagic bleeding disturbances. Three months after daily 400 to 600 mg Danazol an amenorrhea ensued. Steroid determinations during drug administration were complemented by endometrial biopsy in the amenorrheal state. Samples were studied light and electron microscopically. Upon Danazol-treatment the endometrium showed a patterns resembling that in atrophy or in early proliferations stage of the menstrual cycle. This corresponded to estrogen values obtained. In 3 out of 15 cases the pseudosecretory transformation of the endometrium was observed which is explained by the interaction between Danazol and progesterone receptors.

Adult↗
PubMed1988

Cytochemical examinations of Ca, cytochrome oxidase and succinate dehydrogenase enzymes in endometrium carcinomatous tissue after high dose progestogen treatment.

Authors investigated the effect of high dose progestogen in endometrium carcinomatous tissue on the distribution of calcium depots, as well as on the chemically detectable activity of cytochrome oxidase and succinate dehydrogenase. By means of electron microscopy no characteristic destructive effect could unequivocally be demonstrated; cytochemical examinations showed a very significant activity of cytochrome oxidase, and in the activity of succinate dehydrogenase a considerable decrease was observed. They found distributional alterations in plasma membranes, in mitochondria and in the ground cytoplasm. Changes between Ca depots are thought to have an effect on tumour cells also in a protective way, and can be regarded as compensatory phenomena.

Antineoplastic Agents↗