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Biomedical subjects

I Baba

Publications and source records attributed to I Baba.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Functional proteomics of receptor-Ck in the developmental stages of human atherosclerotic arterial wall.

BACKGROUND: The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall. METHODS AND RESULTS: Gene expression study of 25 aortas was undertaken and the results revealed a gradual increase in receptor-Ck gene expression paralleled by the regulatory response of its effector genes coding for sterol response element-binding protein, p27, cyclin D, interleukin-6 and CD40 from a normal to atherosclerotic arterial wall (viz. fatty streak and fibrofatty/fibrous plaque). CONCLUSIONS: Based upon this and our earlier studies, we propose that cholesterol-specific receptor-Ck-dependent gene regulation may be of crucial importance in atherogenesis.

Aorta↗
PubMedDate not supplied

A comparative study regarding the morphological alteration on the gastric level after the administration of piroxicam and complexes with bio-ions Cu(II), Co(II), Zn(II) to rats.

The complex combinations of Piroxicam (Pirox) with the metallic bio-ions: Cu(II), Co(II), Zn(II) have been obtained and defined in a previous stage by physical-chemical methods (IR, X, SM, CSS-UV, DTA, DTG), an toxicological and biochemical aspect. In this research are presented the results of the histological examinations at the level of stomach, for each compound, at 24 hours and at 7 days after the administration of the Piroxicam and of its complexes to rats. The tissues histo-pathological investigation has pointed out lesions the glandular stomach level (necrosis, ulcers) especially after the administration of the Piroxicam and of the Zn-Pirox complex. Name of these have been present after the administration of Cu-Pirox, Co-Pirox.

Animals↗