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Biomedical subjects

I B Van Rensburg

Publications and source records attributed to I B Van Rensburg.

13 recordsLinked to original sources
PubMed1994

Cardiomyopathy in ostriches (Struthio camelus) due to avocado (Persea americana var. guatemalensis) intoxication.

Nine out of 120 ostriches died from congestive heart failure within 96 h of ingesting avocado leaves and immature fruit in an avocado orchard containing Hass and Fuerte cultivars. Foliage and immature fruit from both cultivars dosed to ostriches (n = 4) and domestic hens (n = 8) resulted in severe cardiomyopathy in all the ostriches. In the hens, which had received a lower dose, milder lesions occurred. Macroscopically the intoxication in ostriches resulted in a severe anasarca of the neck and ventral body. The cardiomyopathy was characterised by degeneration and necrosis of myocytes, a marked infiltration of heterophils and in one case, early fibroplasia.

Animals↗
PubMed1993

[Suspected inherited granulocytopathy in four Holstein Friesian calves].

Five Holstein Friesian calves varying in age from 7 to 9 weeks old, were suspected of suffering from an inherited granulocytopathy known as bovine leucocyte adhesion deficiency (BLAD). Four of them were examined clinically and at necropsy. The most significant clinical findings were fever, depression, weakness, emaciation, diarrhoea, pseudomembranous gingivitis, loose teeth, respiratory infection and occult blood in the faeces. Significant clinicopathological findings were marked leucocytosis, mainly due to a neutrophilia, hypoalbuminemia, hypogammaglobulinemia, increased alpha- and beta-globulins, elevated alkaline phosphatase enzyme activity, hypoglycaemia, and decreased blood urea concentrations. The necropsy revealed emaciated carcasses, granulomatous to necrotising gingivitis, pseudomembranous to necrotising enteritis with perforations, bronchopneumonia, splenic atrophy, and hypoplasia of the thymus. Histopathological examination supported the macroscopic findings.

Animals↗
PubMed1991

Molluscum contagiosum in a horse.

An adult stallion presented with a severe papular dermatitis of especially the neck, chest and genitalia. A marked scrotal oedema was present. Histopathological examination of skin biopsies, revealed the presence of numerous intracytoplasmic molluscum bodies in areas of focal epidermal hyperplasia. Electron microscopical examination showed the presence of typical pox virions in affected epidermal cells. Attempts at viral isolation were unsuccessful. This is believed to be the first reported case of molluscum contagiosum in a horse in the Republic of South Africa.

Animals↗
PubMed1990

Systemic cryptococcosis in a cat.

A three-year-old, castrated, male, domestic cat presented with an antibiotic-resistant rhinitis, generalised lymphadenopathy, and skin nodules distributed over the neck, thorax and abdomen. Cryptococcus neoformans was identified on cytology and histopathology specimens, and cultured from all the specimens submitted. The cat died without antimicrobial therapy being instituted. Systemic cryptococcosis was confirmed on necropsy. Lesions were found in the upper and lower respiratory tracts, skin, subcutis, skeletal musculature, lymph nodes, kidney, eye and brain. This report details a case of systemic cryptococcosis in a cat and gives a review of feline cryptococcosis.

Animals↗
PubMed1987

Parasitic pneumonia in a dog caused by a lung fluke of the genus Paragonimus.

Post mortem examination of a dog that died after a spell of respiratory distress revealed about 20 randomly distributed cystic lesions in the lungs. Those examined each harboured 2 light-brownish conical flukes approximately 10 mm in length. Histopathological examination of such a lesion revealed the presence of Paragonimus (lung fluke) embedded in it. The parasite had a typical spiny integument as well as other characteristics typical for the genus. Typical pigmented operculated eggs were embedded in the surrounding tissues. The life cycle of the parasite is briefly discussed.

Animals↗
PubMed1986

Bacterial myocarditis secondary to parvovirus enteritis in a puppy.

A purulent bacterial myocarditis, secondary to parvovirus enteritis was diagnosed in a 3-month-old St Bernard puppy. The clinical course was of 2 days duration and was characterized by pyrexia, severe vomition, haemorrhagic diarrhoea and dehydration. Post mortem examination revealed a haemorrhagic enteritis and multifocal purulent myocarditis. Histopathological examination proved that the latter was of bacterial origin. It is postulated that this resulted from a bacteraemia secondary to the intestinal lesions caused by parvovirus infection.

Animals↗
PubMed1986

Pathology of canine lentiginosis profusa.

Lentiginosis profusa was diagnosed in 3 pedigree Pugs namely two unrelated parents and their female offspring. Macroscopically the lentigines appeared as black macules up to 10 mm in diameter and occurred especially in the skin of the ventral parts of the body. Skin biopsies revealed localised acanthosis and hyperkeratosis with prominent rete ridges and epidermal hyperpigmentation in the absence of any other significant dermal pathology.

Animals↗
PubMed1984

Inanition in a Derby eland due to foreign body abomasitis.

An adult Derby eland bull, Taurotragus derbianus (Grey) kept in captivity showed wasting over a period of 3 months. It died from acute inhalation pneumonia while being transported in an immobilized state. Post mortem examination revealed a chronic ulcerative abomasitis. Histopathologically it was established that the abomasitis resulted from penetration of the mucosa by awns of plant material.

Abomasum↗
PubMed1984

Concomitant feline infectious peritonitis and toxoplasmosis in a cheetah (Acinonyx jubatus).

Three wild caught littermate cheetahs succumbed to feline infectious peritonitis (FIP) after being in captivity for approximately 9 weeks. A necropsy and histopathological examination on one revealed typical signs of FIP as well as histopathological lesions in the liver and brain of concomitant toxoplasmosis. Hypochromic anaemia, neutrophilia, lymphopaenia, eosinopaenia and elevations of alpha 2-globulin and gamma-globulin fractions of the blood were present in the one animal examined. These findings together with some clinical signs are reported.

Acinonyx↗
PubMedDate not supplied

Close relationship between equine and human molluscum contagiosum virus demonstrated by in situ hybridisation.

To determine whether the virus responsible for human molluscum contagiosum (MCV) is the causal agent of a similar disease in horses, in situ hybridisations using cloned fragments of human MCV DNA labelled with digoxigenin were carried out on formalin-fixed biopsy sections of lesions from two horses with molluscum contagiosum-like skin lesions. In both instances there was evidence of specific hybridisation of the labelled probe to target DNA in the sections under high stringency conditions, identified by the development of a deep blue-purple stain in the cytoplasm of cells in the stratum spinosum and stratum granulosum of the lesions and the absence of non-specific hybridisation in adjacent non-lesional areas of the epidermis. These results indicate that on the basis of very close homology of their viral DNA sequences, the causative virus of equine molluscum contagiosum is either identical with, or very closely related to, its human equivalent.

Animals↗