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Biomedical subjects

I Azuma

Publications and source records attributed to I Azuma.

At least 379 records · Page 21Linked to original sources
PubMed1973

Cell wall of Mycobacterium lepraemurium strain Hawaii.

The chemical properties of the cell wall of Mycobacterium lepraemurium strain Hawaii were investigated. Five subunits of the cell wall, arabinose mycolate, mycolic acids, tetrapeptide (Ala-Gln-diaminopimelic acid-Ala), disaccharide (N-acetylglucosaminyl-beta-1,4-N-glycolylmuramic acid), and arabinogalactan, were obtained, and their chemical structures were identified.

Amino Acids↗
PubMed1972

Biochemical studies on the thermal dimorphism of Paracoccidioides brasiliensis.

The biochemical and morphological changes of the yeastlike (Y) form to the mycelial (M) form of Paracoccidioides brasiliensis were examined. The main polysaccharide of hexoses of the Y-form cell wall was alpha-glucan, whereas the polysaccharides of the M-form cell wall were beta-glucan and galactomannan. The alpha-glucan of the Y form contained mainly alpha-(1 --> 3)-glycosidic linkage. The beta-glucan of the M form contained mainly beta-(1 --> 3)-glycosidic linkage with a few branches at C-6 position. The incorporation of (14)C-glucose into the cell wall glucans showed that synthesis of alpha-glucan decreased rapidly after the temperature of the culture was changed from 37 to 20 C. The synthesis of beta-glucan was augmented at an early stage of the morphological change. The M-form cell wall contained 12 times more disulfide linkage than the Y form. The cell-free extracts of the whole cell of the Y form had five times more protein disulfide reductase activity than the M form, whereas extracts of the M form contained five to eight times more beta-glucanase activity than the Y form. From these results, a hypothesis for the production of the M form from the Y form is proposed.

Acetates↗