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Biomedical subjects

I Antener

Publications and source records attributed to I Antener.

At least 37 records · Page 2Linked to original sources
PubMed1977

Dietary treatment of malnutrition. Balance-sheets of the main nutrients. Part II.

Results of a balance study of nitrogen, fat, electrolytes and trace-elements (Fe, Cu, Zn, Mn) with 3 1/i to 9 years old malnourished children in the Kwilu region (Zaïre) are given. The main components of the diets were fish, lactose free milk, caseinate, partial hydrolasate of albumin, fermented corn and soya (Soy-Ogi), medium-chain triglycerides, rice and the local foods manioc, peanuts and caterpillars. The lactose free milk and the Soy-Ogi were well tolerated since we found only a small quantity of non absorbed sugar in the faeces. Our results show that in children who have secondary intestinal malabsorption the use of a partial hydrolysate of lactalbumin and the medium-chain triglycerides is recommended and the substitution of the manioc by rice also. Caseinate gave satisfactory results in adult-malnutrition. We found a good retention of nitrogen, fat and phosphorus. For the latter an addition was necessary. The potassium balance was also positive, a content of 5 meq/kg body weight in the food gave a sufficient retention time. The sodium chloride content of the diet must be moderate because of the oedemas (2 meq/kg body weight). The determination of the vitamin content in the diet and their urinary excretion gave some indication of the balance of these nutrients. Children who had intestinal troubles showed only a slight positive or negative balance of calcium, magnesium, zinc, copper and manganese, since we found a high faecel excretion for these elements. These rather unsatisfactory results emphasis the necessity of first curing any intestinal aliments.

Carbohydrate Metabolism↗
PubMed1977

[Still another cause of hypermethioninemia in children: S-adenosylmethionine synthetase deficiency].

One case of hypermethioninaemia discovered on systematic neonatal screening examination is reported. This metabolic disorder was associated with growth retardation, anorexia, digestive disturbances, and a strong smell of "boiled cabbage" in urine and sweat. With a 6-year follow up, psychomotor and growth developments were excellent under a low methionine containing diet, in spite of a persistent pathological hypermethioninaemia. A deficiency in S-adenosyl-methionine synthetase and an abnormal kinetics of this enzyme were found in a liver tissue sample obtained by biopsy. Otherwise, the excretion of alpha-keto-gamma-methyl-thiobutyric acid was increased with, however, no abnormality in the metabolism of folates. Finally, the probability of an autosomal recessive transmission is discussed.

Amino Acid Metabolism, Inborn Errors↗