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Biomedical subjects

I Akiguchi

Publications and source records attributed to I Akiguchi.

At least 289 records · Page 16Linked to original sources

Krypton-81m single photon emission tomography and the collateral circulation in carotid occlusion: the role of the circle of Willis and leptomeningeal anastomosis.

Cerebral perfusion images were investigated in patients with carotid artery occlusion, using single photon emission computed tomography with the infusion of krypton-81m into the internal, common carotid and vertebral arteries. The contribution of the circle of Willis and cerebral cortical anastomoses to the maintenance of adequate blood supply into the involved hemisphere was analysed. It was concluded that the cerebral perfusion image is superior to angiography in evaluating collateral circulation, and in the case of carotid occlusion, the circle of Willis is important in preventing infarction in the territory of the perforating arteries, while the cerebral cortex mainly receives its blood supply through the cortical leptomeningeal anastomoses, illustrating the major role of the leptomeningeal anastomosis as a collateral channel.

Adult↗

Symptomatological classification in the development of stroke in stroke-prone spontaneously hypertensive rats.

The developmental course of cerebrovascular diseases was examined by comparative neurological and pathological studies in stroke-prone SHR (SHRSP) which died spontaneously or were sacrificed. Behavioral status during their life span could be simply divided into 4 patterns, i.e., "no abnormalities", "irritable", "lethergic" and "akinetic" named Grades 0, I, II and III, respectively (Yamori's Classification). Grades I, II and III of behavioral status corresponded well to symptomato-pathoanatomically divided 3 stages (relating to brain edema), i.e., Stages I, II and III, respectively.

Animals↗

Sarcoid myopathy with typical rash of dermatomyositis.

A 46-year-old woman had heliotrope erythema, poikiloderma, and proximal muscle weakness. Histologic examinations of the skin were consistent with dermatomyositis. Muscle biopsy revealed numerous noncaseating granulomatous lesions within the muscle fasciculi, confirming the diagnosis of sarcoid myopathy. No granulomatous lesion could be detected clinically in other organs. A combination of this skin and muscle disorder is rare and has not been reported previously.

Biopsy↗