Tokelau Islands children's growth.
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Biomedical subjects
Publications and source records attributed to I A Prior.
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The pattern of fasting serum lipids, with emphasis on high density lipoprotein cholesterol, and the relationship of the lipids with each other and with other risk factors is examined in a population based sample of New Zealand Maoris. There are no sex differences in the distribution of total cholesterol and cholesterol fractions but triglycerides are higher in men. High density lipoprotein cholesterol levels are lower in Maoris than reported in other populations. High density lipoprotein cholesterol is negatively correlated with low density lipoprotein cholesterol but not associated with total cholesterol. High density lipoprotein cholesterol is negatively correlated with body mass index and in men high density lipoprotein cholesterol levels are higher in current alcohol drinkers. The possible relationship between the low levels of high density lipoprotein cholesterol and the high risk of coronary heart disease in Maoris requires investigation.
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Analyses for zinc and copper were performed in samples of serum, hair, toenails, and a 24-hr urine from Polynesian men and women resident in the Tokelau Islands. Selection of subjects was according to rank of systolic blood pressure obtained in a previous survey. The only difference in zinc anc copper values between the men and the women was a higher hair zinc concentration observed for the men. Rank of blood pressure had no influence on the measurements for zinc or copper, although within blood pressure ranks the men again had a higher hair zinc concentration than the women. Analysis of Tokelauan foods showed that most contained very low concentrations of zinc anc also low concentrations of copper. Octopus was one of the few rich sources of zinc and copper. Estimated daily dietary intakes (excluding water) were 4.5 mg Zn and 1.5 mg Cu. The reliability of measurements in serum, urine, hair, and toenails for assessing zinc and copper status is questioned.
Results are reported from the first prospective study of gout in New Zealand Maoris based on a sample of 388 males and 378 females. At baseline, high mean levels of serum uric acid (SUA) were found, 0.422 +/- 0.092 mmol/1 (7.05 +/- 1.54 mg/100 ml) in males and 0.350 +/- 0.091 mmol/1 (5.85 +/- 1.52 mg/100 ml) in females. On the basis of traditional criteria (SUA above 0.42 mmol/1 (7.0 mg/100 ml) in males and above 0.36 mmol/1 (6.0 mg/100 ml) in females) the prevalence of hyperuricaemia was 49% in males and 42% in females. The baseline prevalence of gout (8.8% for males and 0.8% for females) and the subsequent 11-year incidence rates (10.3% for males and 4.3% for females) are discussed in relation to specified SUA classes. When traditional, sex-specific criteria for hyperuricaemia were used, no relationship was found between the prevalence of hyperuricaemia and the incidence of gout. There was, however, a sharp increase in the incidence rate of gout in both sexes when SUA levels were above 0.48 mmol/1 (8.0 mg/100 ml). In subjects with a baseline SUA above this level, the age-standardised 11-year incidence rate of gout was 29.1% for males and 37.2% for females. A previously unreported relationship linking muscle size to the incidence of gout in males is presented as a major finding of the study. Other risk factors associated with gout were body mass and blood pressure.
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Three categories (none, mild, and moderate) of varicose veins are studied, and the independent variables studied are race, age, sex, height, weight. Quetelet index and parity. In Maoris the age standarised prevalence rates of varicose veins are 36.3 percent in males and 47.4 percent in females. In Pakehas the rates are 21.6 percent in males and 40.4 percent in females. In both sexes Maoris have a significantly higher prevalence of the more severe category of varicose veins. All variables studied were associated with the prevalence of varicose veins although the relationships vary by race and sex. In the univariate analyses the only variable that distinguished the three categories of varicose veins was parity in Maori females. In the multivariate analyses only in Maori males was a significant discrimination between the three groups of varicose veins achieved although "suggestive" discriminations were also achieved for females of both races.
This paper describes and compares health indicators in Maori and European adolescents attending a coeducational secondary school in New Zealand. No important differences were found in certain urinary constituents, haemoglobin or packed cell volume, fasting plasma glucose, serum urea nitrogen, pulse rate, age of menarche, hospital experience or tuberculin test-BCG status.
The Tokelau Island Migrant Study has shown no important differences between those who subsequently left their home islands to migrate to New Zealand and those who remained, in key anthropometric and biochemical variables already reported. This comparison is now extended to various common diseases and conditions, and again no major difference emerges. The Tokelauans are compared with other Polynesians and shown to have less diabetes, hypertension, effort pain, chronic bronchitis and varicose veins than New Zealand Maoris, while resembling some Cook Island groups. Changes in prevalences of some conditions following migration are postulated.
This paper reports the prevalence of coronary heart disease (CHD) and its relationship with several standard risk factors in samples of New Zealand Maoris and Pakehas. The age standardised prevalence rates of CHD are: 16.1 percent, and 7.3 percent in Maori females and males respectively, and 11.5 percent and 6.5 percent in Pakeha females and males respectively. In Maori females only serum uric acid is associated with an increasing prevalence of CHD. The high prevalence of CHD in females as compared with the higher national mortality rates for males suggests that the case fatality rates for CHD are higher in males. The lack of association between CHD and the risk factors in Maori females suggests the possibility of two syndromes of CHD in Maori females.
A survey in a New Zealand high school compared boys and girls, Maori and European, aged 13 to 15 years, and found differences in smoking habits. Smoking was most prevalent in Maori students of both sexes, and least in European girls, who appeared to be most influenced by home factors such as father's occupational status and older siblings' habits. Maori students and European boys showed relationships rather to the habits of the peer group. Findings were comparable with earlier studies suggesting little secular change in the smoking habits of this age group. Current smokers in all sex/race groups had higher current respiratory morbidity scores than non-smokers and ex-smokers, and smoking partly accounted for racial differences in morbidity.
The family aggregation of blood pressure was studied in Tokelau Island children aged 5-14 years and their parents resident on their home islands in 1971. Five hundred and two (97 per cent) of the children had a recorded blood pressure and they formed 210 sibling groups. The sibship similarity of blood pressure z scores adjusted for year of age and sex was examined by analysis of variance between and within sibships in the 133 sibships with more than one member. For both systolic and diastolic pressure a statistically significant sibship similarity exists which is independent of family size, level of pressure, and the sibship similarity of Quetelet Index. The correlation coefficient of the z score of one index child chosen at random and the remaining siblings is 0-14 (n = 282, p = 0-017). Of the parental variables studied the mother's systolic pressure is the best, and only, predictor of the child's systolic z score. These results suggest that in the Tokelau islanders a family similarity of blood pressure is established relatively early in life.
Two hundred and ninety-four New Zealand secondary school students were examined by questionnaire, and physical and biochemical methods. The sample contained almost equal numbers of Maoris and Europeans. The findings related to joint conditions are presented. Past injury and rheumatic disease accounted for some of the reported morbidity, but no important sex or race differences in these factors emerged. There were, however, significant differences in serum uric acid levels with the Maori having higher levels than the Europeans. A significant correlation with body mass was present in both race and sex groups but a correlation with haemoglobin was present only in the European females. While hyperuricaemia was not associated with morbidity in this young sample, ethnic differences anticipated the higher prevalence of gout already observed in Maori men.
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