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Biomedical subjects

I A Izotova

Publications and source records attributed to I A Izotova.

6 recordsLinked to original sources
PubMed1992

[Tumor markers MCA and CA-125 in the diagnosis and monitoring of breast cancer].

The value of MCA and CA-25 tumor marker assays for diagnosis and treatment of breast cancer was analysed on the basis of measurements made in 320 healthy females and 85 breast cancer patients. A procedure for DK assay with anticipated specificity, sensitivity and reliability is described. MCA measurement was shown to be important for breast cancer diagnosis. The reliability of the latter test for diagnosing progression in the course of follow-up was 91%. Progression of the disease was shown to be associated with an increase in blood CA-125 level in 60% of cases.

Adult↗
PubMed1984

[The state of hormonal homeostasis in patients with lung cancer under combined and radiation treatment].

Radioimmunologic evaluation of hormonal profile was performed in 200 lung cancer patients before and after combined and radiation treatment and in 25 healthy subjects (controls). The study showed an increase in the basal level of hormones of pituitary-adrenal system matched by a decline in thyroid function. Adequate combined and radiation treatment brought hormone levels to normal. Hormonal disorders accompanying recurrence were identical to those registered at disease onset. In some cases, changes in hormonal profile developed as early as 3-6 months prior to clinically manifest recurrences or dissemination.

Adenocarcinoma↗
PubMed1980

[Functional state of the hypophyseal-adrenal system in lung cancer].

The results are reported on studies of the secretion of adrenocorticotropic (ACTH), somatotropic (STH) hormones and cortisol, using a standard set for in vitro diagnosis. A total of 66 patients aged 31--70 (64 males and 2 females) have been examined. Among these patients stage II was noted in 17, stage III--in 31, stage IV--in 18. In 19 of them a peripheral cancer and in 47--central cancer was detected. The data obtained indicate an increased basal level of ACTH, STH, cortisol which is directly dependent on the cancer process stage. The maximum increased level of these hormones was noted in low differentiated cancer of the lung.

Adenocarcinoma↗