Biomedical subjects

Howard V Gimbel

Publications and source records attributed to Howard V Gimbel.

7 recordsLinked to original sources

PubMed2003

Topical thiotepa treatment for recurrent corneal haze after photorefractive keratectomy.

PURPOSE: To describe the use of topical thiotepa in the treatment of recurrent haze after photorefractive keratectomy (PRK). SETTING: Gimbel Eye Centre, Calgary, Alberta, Canada. METHODS: Five patients with recurrent haze after myopic PRK were retreated with phototherapeutic keratectomy and topical thiotepa. Before retreatment, the best corrected visual acuity (BCVA) ranged from 20/40 to 20/200. Follow-up ranged from 3 to to15 months. RESULTS: Haze, uncorrected visual acuity (UCVA), and BCVA improved in all patients. Three eyes had a UCVA of 20/20(-2) or better and a BCVA of 20/20(-1) or better. The other 2 eyes experienced regression of the myopia and astigmatism and had a BCVA of 20/25(-1) or better. CONCLUSION: Topical thiotepa appeared to be an effective treatment for recurrent corneal haze following myopic PRK.

Administration, Topical↗

PubMed2003

AdvanTec Legacy System and the NeoSoniX handpiece.

AdvanTec Legacy System and the NeoSoniX handpiece (Alcon Surgical, Fort Worth, Texas) are improvements to the Legacy System that allow power modulation and customization of surgical technique in phacoemulsification surgery. AdvanTec technology allows power modulation in terms of occlusion power management, global linear flow, mode sequencing, and visco mode. The NeoSoniX handpiece combines sonic oscillations with linear ultrasound to reduce thermal energy during nucleus removal. The AdvanTec System allows lower power, less delivered energy, a lower risk of thermal burns, less chatter, and improved followability during phacoemulsification. These improvements translate into successful clinical outcomes.

Clinical Trials as Topic↗

PubMed2002

Management of myopic astigmatism with phakic intraocular lens implantation.

A 48-year-old woman presented with a manifest refraction of -9.25 -2.25 x 98 that resulted in a best corrected visual acuity (BCVA) of 20/20(-2) in the right eye. She was contact lens intolerant but was not a good candidate for laser in situ keratomileusis because of a thin cornea. A phakic posterior chamber intraocular lens (IOL) with a toric optic was implanted with no operative complications. One day after surgery, the uncorrected visual acuity (UCVA) was 20/15. Five months postoperatively, the UCVA in the operated eye was 20/15 with a manifest refraction of +0.25 -0.25 x 60 and a BCVA of 20/15. No changes to the crystalline lens or anterior lens capsule were seen. This is the first report of implantation of a toric phakic IOL in North America.

Astigmatism↗

PubMed2002

Advances in phacoemulsification equipment.

The purpose of this article is to update information on the phacoemulsification equipment based on a systematic review of available literature within the past year. Phacoemulsification has gained acceptance as the standard technique for cataract surgery worldwide, and new phacoemulsification techniques and equipment have been reported. The authors conducted a MEDLINE literature search from August 2000 to the present. Software and hardware upgrades in ultrasound phacoemulsilification equipment have not been found in peer-reviewed publications this past year. Lasers for cataract surgery have been reviewed to a limited extent. Ultrasound phacoemulsilification is well established. Alternative methods of nuclear disassembly are being evaluated and reported.

Humans↗

PubMedDate not supplied

Primary multipoint (segmental) custom ablation.

PURPOSE: We present our experience in resolving visual symptoms in refractive patients undergoing primary multipoint (segmental) custom ablation. METHODS: Twelve eyes with mixed myopic astigmatism underwent evaluation and primary treatment by multipoint (segmental) custom ablation for the correction of refractive errors and visual symptoms using the Nidek NAVEX platform. RESULTS: Twelve eyes showed resolution of visual symptoms following diagnosis and treatment with MCA using the NAVEX platform. No patient lost two or more lines of best spectacle-corrected visual acuity. The postoperative root mean square of higher order aberrations did not change in a predictable or reproducible fashion. CONCLUSION: Multipoint (segmental) custom ablation with the Nidek NAVEX system was safe and effective for correcting mixed myopic astigmatism and for resolving visual symptoms in selected refractive surgery candidates. Small changes in the root mean square of higher order aberration values were not always reflected in a patient's subjective assessment of vision quality.

Adult↗

PubMedDate not supplied

Wavefront-guided multipoint (segmental) custom ablation enhancement using the Nidek NAVEX platform.

PURPOSE: To present our clinical experience regarding enhancement (retreatment) of previously performed non-wavefront-guided refractive surgery by wavefront-guided multipoint (segmental) custom ablation utilizing the Nidek NAVEX platform. METHODS: Retrospective clinical analysis was conducted of 20 eyes (19 patients) with mixed myopic or hyperopic astigmatism who had undergone primary laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) and reported postoperative reductions in quality of vision. These vision disturbances correlated with clinically significant elevations in the root mean square of higher order aberrations (RMS of HOA) values. Before wavefront-guided multipoint (segmental) custom ablation enhancement with the NAVEX platform, all patients underwent testing with the Nidek Optical Path Difference Scan (OPD-Scan) and analysis with Final Fit Software. RESULTS: Twenty eyes showed improvement or resolution of visual symptoms following wavefront-guided multipoint (segmental) custom ablation enhancement. The postoperative root mean square of higher order aberration values were variable and not always related to improvement in visual function. No patient lost two or more lines of best spectacle-corrected visual acuity. CONCLUSION: Topography and wavefrontguided multipoint (segmental) custom ablation enhancements were safe and effective in improving visual symptoms following primary refractive surgery. In some eyes, improved visual function without correspondingly lower RMS of HOA values may be an effect of neutralizing some chromatic aberrations across the visible light spectrum, thereby improving the modulation transfer function.

Adult↗

PubMedDate not supplied

Clinical applications of capsular tension rings in cataract surgery.

BACKGROUND: Although the open capsular tension ring was designed to manage zonular dialysis during cataract surgery, it also lowers the incidence of capsule contraction, stabilizes the capsular bag, and enhances IOL centration. With appendages, it provides a partial solution for those eyes with colobomata and aniridia. MATERIALS AND TECHNIQUES: Subsequent modifications to the capsular tension ring include the Cionni ring, capsular edge ring, coloboma ring, and aniridia ring. A square-edge design may inhibit posterior capsule opacification, and the aniridia and coloboma rings with appendages create an artificial it is in traumatic or congenital colobomata. RESULTS: Designs, functions, indications, and results of different types of capsular tension rings are reviewed, as well as applications in pediatric cases, and considerations for their routine use in adult cataract surgery. CONCLUSIONS: The potential benefits of capsular edge ring implantation in pediatric cataract surgery cases are explored.

Adult↗