Hongyu Liu — Page 2 | Search PubMed

PubMed2002

[On the safety threshold of wetlands based on water ecological element--taking wetlands in Sanjiang Plain as an example].

The lowest water requirement of the wetlands was demonstrated through different simulations. Based on the relationship between the area of wetlands and its effects on air temperature and humidity, some useful statistical models were established. According to the theory and principles of system dynamics (SD), a dynamic simulation model of the wetlands' retaining water was compiled in DYNAMO language. Finally, the safety threshold of the wetlands was assessed based on its water ecological factors. The feasibility of the method was demonstrated by a case study on the wetlands in Sanjiang Plain of China.

Agriculture↗

PubMed2000

[A Nude Mouse Model for Human Umbilical Cord Blood Transplantation]

To evaluate the hematopoietic potentiality and the migration and homing routine of separated as well as cryopreserved umbilical cord blood hematopoietic cells, the BALB/cnu(+) mice were used to establish a murine model. This can prepare for the clinical transplantation and the establishment of a large-scale cord blood bank. The result indicated that the hydroxyethyl starch (HES) sedimentation and DMSO step-by-step cryopreservation procedure resulted in only less losses of hematopoietic progenitor cells and also unharmful to the hematopietic potentiality. We can found evidence for successful transplantation in each mouse which received (1.0 - 2.0) x 10(7) separated or cryopresered hematopoietic cells from cord blood, which lasted for about fifty days. The results demonstrated that (1) HES sedimentation and DMSO cryopreservation procedure can keep the hematopoietic potentiality of cord blood, and so can be used to clinical transplantation or establishment of a cord blood bank; (2) Rich hematopoietic stem cells in human cord blood can cross the xenogenetic barriers and successfully engraft mice; (3) The hematopoietic cells migrated among bone marrow, liver, spleen, lung and kidney in the mice and homed to bone marrow by the end. Cryopreservation may influence the adhesion molecule on the hematopoietic cells and the homing behaviour, but not influence their hematopoietic potentiality.

Journal Article↗