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Biomedical subjects

Holly A Taylor

Publications and source records attributed to Holly A Taylor.

15 recordsLinked to original sources

Effect of an afternoon confectionery snack on cognitive processes critical to learning.

Two experiments examined how an afternoon confectionery snack affects a variety of cognitive processes critical to learning. For Experiment 1, thirty-eight male undergraduates completed a dual learning task where the primary task involved learning either a map or stories and the secondary task required monitoring a radio broadcast for a specific word category. Results showed that for map learning, participants who consumed the confectionery snack performed better on the primary task. They correctly placed more country names and left fewer blanks on a map during long-term recall. However, on the secondary attention task, participants who consumed the confectionery snack had a lower hit rate. The confectionary snack did not affect story memory performance. In Experiment 2, 38 boys, aged 9-11 years, participated in a similar, age appropriate task. Results showed that boys who had consumed the confectionery snack correctly placed more names and left fewer blanks on a map in both short-term and long-term recall. In contrast with Experiment 1, performance on the secondary task was better after confectionary consumption. However, when tested on a separate vigilance attention task, children who consumed the placebo performed better. Overall results indicate that a confectionery snack, ingested in the afternoon, generally improves spatial memory, but has a mixed effect on attention performance.

Adolescent↗

Formative research in clinical trial development: attitudes of patients with arthritis in enhancing prevention trials.

In preparation for randomised controlled trials (RCTs) of disease-modifying antirheumatic drugs in patients with early inflammatory arthritis (EIA), formative research was conducted to enhance the design of such trials. The objectives of this research were to (1) determine patients' educational needs as they relate to the necessary elements of informed consent; and (2) assess patients' interest in enrolling in a hypothetical prevention trial. In-depth interviews were conducted with nine patients. Seven patients were women and all but one white. The mean age was 48 years. During the 4-month enrolment period, only three patients with EIA were identified; six patients with longer duration of symptoms were also interviewed. Most patients were able to express the primary aim of a hypothetical prevention trial presented. Factors cited by patients favouring enrolment were potential for direct medical benefit and knowledge that they would be withdrawn from the trial if they developed symptoms. Factors cited by patients against enrolment were the inclusion of a placebo and general uncertainty regarding treatment required by the RCT design. Pending larger-scale empirical projects to explore patients' attitudes about prevention trials, small-scale formative research in advance of such trials ought to be conducted.

Adult↗

Words and maps: developmental changes in mental models of spatial information acquired from descriptions and depictions.

People acquire spatial information from many sources, including maps, verbal descriptions, and navigating in the environment. The different sources present spatial information in different ways. For example, maps can show many spatial relations simultaneously, but in a description, each spatial relation must be presented sequentially. The present research investigated how these source differences influence the mental models that children and adults form of the presented information. In Experiment 1, 8-year-olds, 10-year-olds and adults learned the layout of a six-room space either from verbal descriptions or from a map. They then constructed the configuration and pointed to target locations. Participants who learned from the map performed significantly better than those who learned from the description. Ten-year-olds performed nearly as well as adults did. The 8-year-olds' mental models differed substantially from the older children's and adults' mental models. The younger children retained the sequential information but did not integrate the relations into a survey-like cognitive map. Experiment 2 demonstrated that viewing the shape of the configuration, without seeing the map in full, could facilitate 8-year-olds' use of the verbal information and their ability to integrate the locations. The results demonstrate developmental differences in the mental representation of spatial information from descriptions. In addition, the results reveal that maps and other graphic representations can facilitate children's spatial thinking by helping them to transcend the sequential nature of language and direct experience.

Adult↗

Character movement and the representation of space during narrative comprehension.

Traditional research on situation models has examined the accessibility of locations and objects during narrative experiences. These studies have described a ubiquitous gradient effect: Spatial locations and objects in reader focus are more accessible than locations farther from this focus, with accessibility decreasing as a function of distance. How might readers' expectations about character movement, beyond information about spatial locations, additionally affect this accessibility gradient? In two experiments, we investigated whether reader expectations for character movement impact the accessibility of spatial information from memory. In Experiment 1, participants read stories that described characters moving in either a unidirectional or a random pattern through a learned environment. In Experiment 2, characters moved forward in a unidirectional way or backtracked through previously explored rooms. The results suggest that reader expectations for character movement can influence the accessibility of spatial information. Such expectations play a critical role in processes of narrative comprehension.

Comprehension↗

Effect of breakfast composition on cognitive processes in elementary school children.

The relationship between breakfast composition and cognitive performance was examined in elementary school children. Two experiments compared the effects of two common U.S. breakfast foods and no breakfast on children's cognition. Using a within-participant design, once a week for 3 weeks, children consumed one of two breakfasts or no breakfast and then completed a battery of cognitive tests. The two breakfasts were instant oatmeal and ready-to-eat cereal, which were similar in energy, but differed in macronutrient composition, processing characteristics, effects on digestion and metabolism, and glycemic score. Results with 9 to 11 year-olds replicated previous findings showing that breakfast intake enhances cognitive performance, particularly on tasks requiring processing of a complex visual display. The results extend previous findings by showing differential effects of breakfast type. Boys and girls showed enhanced spatial memory and girls showed improved short-term memory after consuming oatmeal. Results with 6 to 8 year-olds also showed effects of breakfast type. Younger children had better spatial memory and better auditory attention and girls exhibited better short-term memory after consuming oatmeal. Due to compositional differences in protein and fiber content, glycemic scores, and rate of digestion, oatmeal may provide a slower and more sustained energy source and consequently result in cognitive enhancement compared to low-fiber high glycemic ready-to-eat cereal. These results have important practical implications, suggesting the importance of what children consume for breakfast before school.

Attention↗

When goals collide: monitoring the goals of multiple characters.

Most story plots contain multiple characters who are independent, interact, and often have conflicting goals. One would expect that narrative understanding would require monitoring of the goals, concerns, and situations of multiple agents. There is considerable evidence that understanders monitor the primary protagonist's goal plans (e.g., Suh & Trabasso, 1993). However, there is relatively little research on the extent to which understanders monitor the goals of multiple agents. We investigated the impact of characters' roles and prominence on the extent to which understanders monitor the goal plans of multiple characters in a feature length film. In Experiment 1, participants made situation change judgments, and in Experiment 2, they verbally described scenes. Both types of judgments indicated that viewers monitor the goals and plans of multiple agents but do so to a greater extent for characters more prominent to the plotline.

Adult↗

Interactive dimensions in the construction of mental representations for text.

To detail the structure and format of memory for texts, researchers have examined whether readers monitor separate text dimensions for space, time, and characters. The authors proposed that the interactivity between these individual dimensions may be as critical to the construction of complex mental models as the discrete dimensions themselves. In the present experiments, participants read stories in which characters were described as traveling from a start to a final location. During movement between locations, characters engaged in activities that could take either a long or short amount of time to complete. Results indicate that accessibility for the spatial locations was a function of the passage of time. The authors interpret this as evidence that the interactive nature of text dimensions affects the structure of representations in memory.

Cognition↗

Consent and compensation: a social compact for smallpox vaccine policy in the event of an attack.

In the event of a widespread biological attack involving smallpox, it may not only be morally permissible, but morally obligatory, to dispense with the ordinary requirements of informed consent for vaccination. The government should also commit to educating the public about the vaccine, distributing the vaccine efficiently and fairly, and ensuring access to health care to those who experience adverse events as a result of vaccination. In addition, the government should provide a program of financial compensation for any persons who experience permanent disability as a consequence of vaccination and for the families of those who die as a result of vaccination.

Bioterrorism↗

Readability standards for informed-consent forms as compared with actual readability.

BACKGROUND: Institutional review boards (IRBs) are charged with safeguarding potential research subjects with limited literacy but may have an inadvertent role in promulgating unreadable consent forms. We hypothesized that text provided by IRBs in informed-consent forms falls short of the IRBs' own readability standards and that readability is influenced by the level of research activity, local literacy rates, and federal oversight. METHODS: To test these hypotheses, we conducted a cross-sectional study linking data from several public-use sources. A total of 114 Web sites of U.S. medical schools were surveyed for IRB readability standards and informed-consent-form templates. Actual readability was measured with the Flesch-Kincaid scale, which assigns a score on the basis of the minimal grade level required to read and understand English text (range, 0 to 12). Data on the level of research activity, local literacy rates, and federal oversight were obtained from organizational Web sites. RESULTS: The average readability score for text provided by IRBs was 10.6 (95 percent confidence interval, 10.3 to 10.8) on the Flesch-Kincaid scale. Specific readability standards, found on 61 Web sites (54 percent), ranged from a 5th-grade reading level to a 10th-grade reading level. The mean Flesch-Kincaid scores for the readability of sample text provided by IRBs exceeded the stated standard by 2.8 grade levels (95 percent confidence interval, 2.4 to 3.2; P<0.001). Readability was not associated with either the level of research funding (P=0.89) or local rates of literacy (P=0.92). However, the 52 schools that had been made subject to oversight by the Office for Human Research Protections (46 percent) had lower Flesch-Kincaid scores than the other schools (10.2 vs. 10.9, P=0.005). CONCLUSIONS: IRBs commonly provide text for informed-consent forms that falls short of their own readability standards. Federal oversight is associated with better readability.

Comprehension↗

The effects of a confectionery snack on attention in young boys.

The relationship between consumption of a confectionery snack after an overnight fast and cognitive function was examined using a variety of cognitive tasks, including spatial memory, verbal memory, attention, visual perception and short-term memory, in a sample of 21 boys, ages 9-12 years. Performance on the vigilance attention task was significantly improved when the participants consumed a confectionery snack compared to consumption of a noncalorie snack. Participants had significantly higher hit rates and significantly lower miss rates after the confectionery snack. In addition, false alarm rates increased as a function of time for the placebo condition and decreased for the confectionery condition. Thus, the confectionery snack enhanced ability to stay on task for an extended period of time, enabling the children to more accurately identify target information, as well as correctly reject nontarget information. Analysis of the types of errors made also revealed that when the children were in the confectionery condition they were less likely to make more glaring errors. No significant differences were found in tests of digit span, verbal memory, spatial memory or visual perception.

Attention↗

Neural correlates of spatial term use.

The current research used event-related brain potentials (ERPs) to assess the processes underlying online apprehension of the spatial term above. Constituent steps defined within G. D. Logan and D. D. Sadler's (1996) computational theory of apprehension were associated with distinct modulations of ERPs. Specifically, finding the relevant objects was associated with an amplitude modulation of P3; competition in assigning directions to space was associated with modulation of a frontal slow wave; and computing and comparing the spatial relation was associated with modulation of a parietal slow wave. These modulations were differentially influenced by the type of reference frame used to define the spatial term and by the participant's response. The current study supports this decompositional approach to apprehension and provides a means of assessing each step independently.

Adult↗