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Hiroki Nakabayashi

Publications and source records attributed to Hiroki Nakabayashi.

4 recordsLinked to original sources
PubMed2026

A nationwide survey of pregnant women on their experience with fetal ultrasound examination in Japan.

PURPOSE: Fetal ultrasound examination (FUSE) is a prenatal screening test that can detect fetal structural abnormalities before birth. The purpose of this study was to clarify how pregnant women perceive FUSE and what they expect from it. METHODS: A questionnaire survey comprising 21 questions was conducted using the "Baby Plus" application for pregnant women. The response period was from November 8 to November 30, 2023. The participants were women who were at least 20 weeks of gestation and postpartum mothers within 3 months of delivery. Statistical analyses were performed using the chi-square test. RESULTS: Responses were received from 1,100 women. Sixty-six percent of the women recognized the differences between FUSE and routine ultrasonography. Forty-nine percent had undergone or planned to undergo FUSE, and 87% of those had received an explanation about the test. Many women expressed a desire for detailed explanations about the examination itself. Although less common, some women indicated that they did not wish to undergo fetal ultrasound examinations or learn about fetal abnormalities. Approximately 70% of women reported that they would consider termination of pregnancy if fetal abnormalities were detected. CONCLUSION: There may be a mismatch between pregnant women's expectations regarding FUSE and the way it is currently provided, including the timing of the examination and the explanations given. To help reduce this mismatch and support informed decision-making among pregnant women, greater standardization of FUSE practices and individualized explanations may be beneficial.

Fetal ultrasound examination↗
PubMed2006

[Lowe syndrome].

Explore the source record for details and available documents.

Chromosomes, Human, X↗
PubMed2006

[Magnetic resonance imaging of the brain in phenylketonuria].

To investigate the correlation between the abnormalities of magnetic resonance imaging (MRI) of the brain and blood phenylalanine (Phe) levels in phenylketonuria (PKU) and hyperphenylalaninemia (HPA), we reviewed MRIs from 16 patients with early treated PKU and HPA. Their ages ranged from 4-24 years and were found by mass screening and treated from early infancy, and 5 patients with late detected PKU who were aged 24-33 years. The former patients had no remarkable neurological signs or symptoms. One patient of the latter had severe mental retardation and 3 patients had mild to border mental retardation. Axial T1-weighted and T2-weighted spin echo sequences, fluid attenuated inversion recovery MR sequences (FLAIR) through the brain were performed. The scans were graded according to the extent of increased signal intensity of white matter on T2-weighted and FLAIR sequences. To investigate the influence of plasma Phe levels, three approaches were used. Firstly an average of all yearly serial blood Phe concentration was calculated for each patient, then Phe was determined for a period of 6 months and 12 months prior to MRI, and also for their lifetime up to their age at the time this study began. These average blood Phe levels were classified into four categories: group A:Phe level below 5 mg/dl, group B:5-8 mg/dl, group C:9-12 mg/dl, group D:above 12 mg/dl. MRI findings were not significant in group A. Remarkable high signals of white matter were obtained in group C and D, except for one patient in group D whose MRI finding was normal. MRI findings correlated to long-term dietary control stronger than those of 6 months prior to MRI. The clinical significance of MRI abnormalities is still unclear, and further study is required to clarify the relationship of the MRI findings and clinical conditions.

Adolescent↗