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Biomedical subjects

Haruhiko Abe

Publications and source records attributed to Haruhiko Abe.

38 records · Page 3Linked to original sources

Usefulness of orthostatic self-training for the prevention of neurocardiogenic syncope.

To clarify the effectiveness of an orthostatic self-training program for the prevention of neurocardiogenic syncope, twenty-four consecutive head-up tilt induced syncopal patients (12 men, 12 women; mean age 34 +/- 20 years) were treated with an orthostatic self-training program. The syncope was induced by head-up tilt testing (+ 80 degrees for 30 minutes) with or without the use of isoproterenol in all patients reproducibly. The hemodynamics during the syncope were of the cardioinhibitory type in 4, vasodepressor type in 7, and mixed type in 13 patients. The onset time of the tilt induced syncope was 16 +/- 10 minutes after the upright position. The orthostatic self-training included standing against a wall without moving twice a day every day for a planned duration of up to 30 minutes at home. The head-up tilt response was reevaluated with the same protocol as the initial study after 22 +/- 6 days based on the patient's daily recording of the self-training, and the clinical effect of the training program performed only once a day at home was noted over a mean follow-up of 9.5 +/- 3.4 months (range 5-18 months). Tilt induced syncope after the self-training was observed in 2 of 24 patients. However, spontaneous syncope was not observed in any of the patients during follow-up. In conclusion, orthostatic self-training significantly improved the symptoms in patients with neurocardiogenic syncope. Once a day training for up to 30 minutes was effective and easily accepted by the patients for the prevention of neurocardiogenic syncope.

Adolescent↗

The incidence and risk factors for venous obstruction after implantation of transvenous pacing leads.

Several investigators have shown that the incidence of venous obstruction after pacemaker implantation was observed in 31-50% of pacemaker patients. However, these previous reports did not investigate the venous system prior to implantation. The aim of this study was to determine the incidence and risk factors for venous obstruction in patients with transvenous pacing leads. The study included 131 consecutive patients (64 men, 67 women; mean age 71.3 +/- 9.8 years) who were investigated using intravenous digital subtraction angiography (DSA) before and after permanent pacemaker implantation. Follow-up DSA was performed for a mean interval of 44 +/- 6 months after pacemaker lead implantation in 79 of 131 patients. A diameter narrowing > 60% was defined as an obstruction. Prior to implantation of pacing leads, venous obstruction was present in 18 (13.7%) of 131 patients. In 15 of these 18 patients, the obstruction was present at the site of the left innominate vein. Follow-up DSA, after implantation of pacing leads, showed that venous obstruction was observed in 26 (32.9%) of 79 patients. There were no significant differences between obstruction and nonobstruction groups in terms of age, sex, cardiothoracic ratio, left atrial dimension, left ventricular ejection fraction, baseline heart diseases for indication of pacemaker implantation, or number and body size of pacing leads. Neither clinical symptoms nor abnormal physical findings were observed in any patients. In conclusion, the incidence of venous obstruction after pacing lead implantation is less than that of previous reports, which might be related to the incidence of venous obstruction before pacing leads implantation.

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