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Biomedical subjects

Harald Bailer

Publications and source records attributed to Harald Bailer.

7 recordsLinked to original sources

Two-question depression-screeners - the solution to all problems?

UNLABELLED: Depression constitutes a considerable issue in medicine and it is anticipated that the amount of people suffering from affective disorders will increase significantly. It would be useful to have a simple, fast screening procedure which would help detect depression. In four recently published articles a two-question depression-screener is recommended. METHOD: Sensitivity, specificity, likelihood ratios, negative and positive predictive values were compared. RESULTS: For four different clinical samples and one sample that was representative of the German population the prevalence for depression ranged from 6.9 % to 18.1 %. Sensitivity and specificity reached values from 72.6 % to 96.6 % and from 56.9 % to 90.0 % respectively. All negative predictive values were high (< 97 %) opposed to positive predictive values (17.8 % to 38.5 %). CONCLUSION: Overall, it seems that the two-question screenings are well suited for the exclusion of a major depression. It is possible that regular screening could further lower the percentage of undiagnosed cases.

Adult↗

[Screening for depression -- two questions practically oriented].

Despite the high epidemiological relevance of depressive disorders in daily clinical practice, they are insufficiently diagnosed. For screening, the U.S. Preventive Services Task Force proposed two questions aiming at finding depressive core symptoms: "Over the past two weeks, have you felt down, depressed, or helpless?" and "Over the past two weeks, have you felt little interest or pleasure in doing things?". We tested comparable questions in a representative sample from the German population. The correlations between the screening and validated questionnaires for depression point towards the validity of the screener. Relevant indices are satisfying: For major depression the sensitivity is 72.6% and specificity is 87.4%.

Adolescent↗

Coping and survival in patients with leukemia undergoing allogeneic bone marrow transplantation--long-term follow-up of a prospective study.

OBJECTIVE: The exploratory study examined the relationship between coping and survival in patients undergoing bone marrow transplantation (BMT). METHODS: Patients scheduled for BMT were recruited from 1990 until 1995 at the University Hospital of Ulm, Germany. They were interviewed before transplantation, and the corresponding records were checked in December 2002. Seventy-two audiotaped interviews could be analyzed for 34 coping strategies as defined in the Ulm Coping Manual (UCM). Main outcome measure was survival time post-BMT. RESULTS: On average, the patients were 35 years old, 65% were male, and 56% diagnosed acute leukemia (AL). Four coping strategies were found to show a clear trend towards an association with survival time: emotional support, acceptance, taking control, and compensation. The last strategy was associated with shorter, the others with longer survival. CONCLUSION: We found further evidence for an association between coping and survival. Because of the possible wide-reaching consequences for clinical management, replication of the data is essential.

Acute Disease↗

[The German short version of "Profile of Mood States" (POMS): psychometric evaluation in a representative sample].

The German short version of "Profile of Mood States" (POMS) was psychometrically tested in a representative sample (1009 subjects in Eastern Germany and 1034 subjects in Western Germany). The 35 items (7 point scale, instruction "How you have been feeling during the past 24 hours?") form the following scales: Depression/Anxiety, Fatigue, Vigor, Hostility. The POMS appears to be an internally consistent instrument (Cronbach's Alpha from 0.89 to 0.95). Replication of the postulated 4 factors was limited. There are hints for convergent validity of POMS-Scales using two questions: "1. Over the past two weeks, have you felt down, depressed, or helpless?" and "2. Over the past two weeks, have you felt little interest or pleasure in doing things?"

Adolescent↗

[Religious and spiritual beliefs - validation of the German version of the "Systems of Belief Inventory" (SBI-15R-D) by Holland et al. in a population-based sample].

The present study describes the German version of the "Systems of Belief Inventory (SBI-15R)" developed by Holland et al. The questionnaire was used in a representative sample of 954 eastern and 1031 western Germans. The SBI met tests of internal consistency and demonstrated discriminant validity. But the two factors of the original version could not clearly be replicated. For the relevance of religious beliefs we found that women score higher than men, older score higher than younger, persons with lower education score higher than persons with higher education, western Germans score higher than eastern Germans. Connections between the SBI-15R-D and self-evaluation as being religious and importance of faith during childhood give hints to the instrument's validity. The SBI-15R-D can serve as a valid and economic tool to explore the role of religious and spiritual beliefs.

Adult↗

[Validation and standardization of the "Questionnaire for Assessing Subjective Physical Well-Being" by Kolip and Schmidt in a representative German sample].

The "Questionnaire for Assessing Subjective Physical Well-Being" by Kolip and Schmidt is examined using data drawn from a nationally representative survey of 573 former East and 1900 former West Germans. In this non-clinical sample the construct "subjective physical well-being" assessed by the "Questionnaire for Assessing Subjective Physical Well-Being" seems to have just one dimension. As women and probands with growing age score lower for "subjective physical well-being" a differentiated standardization was done for gender and age. Connections between "subjective physical well-being" and body-image assessed by the "Body Image Questionnaire" (FKB-20), quality of life ("EURO-HIS-QOL"), and questions for concerns about financial situation, family and health give hints for validity of the questionnaire.

Adult↗

[Standardization of the German short version of "profile of mood states" (POMS) in a representative sample--short communication].

The questionnaire "Profile of Mood States (POMS)" is recommended as a measure of mood states in patients and non-clinical samples. On the basis of a representative sample (2043 subjects) reference values for the four scales (DEPRESSION/ANXIETY, FATIGUE, VIGOR, ANGER) of the German short version of the "Profile of Mood States" (POMS--35 items, 7 point scale, instruction "How you have been feeling during the past 24 hours?") are presented. The scale ANGER was independent from variables gender, age, education and current residence. In contrast to the other three scales these differentiations were necessary and detailed reference values are reported.

Adolescent↗