Laser hazards: biomedical threshold level investigations.
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Biomedical subjects
Publications and source records attributed to H Zwick.
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In healthy subjects the pulmonary artery pressure was measured during exercise tests with the aid of the flow guided catheterisation. The work load was determined on bicycle ergometer in recumbent position in form of a multistage exercise test with relative steady state periods till exhaustion was reached. In this way, during the highest work load (200 Watt) the systolic pulmonary artery pressure was 33.9 +/- 5.5 mm Hg, the diastolic pressure 17.5 +/- 3.6 mm Hg and the pulmonary mean pressure 24.7 +/- 4.0 mm Hg. The factors influencing the pulmonary artery pressure during work are discussed.
In our experiments, intense monochromatic coherent light (647.1nm) was used to permanently alter the red cone process. As the turtle (Pseudemys) is very sensitive in the red region of the spectrum, it was chosen as an appropriate animal model in which to study initially experimentally induced protanopia. Dark adaptation and spectral sensitivity functions were measured for ERG criteria using a vector voltmeter. Successive dark adaptation functions were measured for chromatic light adaptation levels from full bleach to about two log units above full bleach, where the dark adaptation was abruptly altered in its dynamic range by about one log unit. Pre- and post-exposure measurements showed the action spectra suppressed in sensitivity by about one log unit from 600 to 660 nm. A small depression in the short wavelength region (420-500nm) was also observed.
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OBJECTIVE: To evaluate cell block preparations as a tool for the diagnosis of pulmonary malignancy and to correlate the findings with those from brush cytology and histology from forceps biopsy. STUDY DESIGN: One hundred twenty consecutive samples from patients with primary or metastatic lung cancer were routinely processed and stained for cytologic and histologic examination. In addition to smears, a cell block was prepared from each brushing sample. Brush smears, cell blocks and biopsy specimens were compared and evaluated for their diagnostic accuracy. RESULTS: Brush cytology samples were interpreted as positive for malignancy in all 120 cases. In 42 cases immunohistochemistry performed on cell blocks led to the final precise type diagnosis. Owing to technical problems (stenosis, bleeding, peripheral location), forceps biopsy specimens were obtained from only 51 patients. CONCLUSION: In addition to lower patient risk, cell block preparation yields high diagnostic accuracy and may thus be considered an improvement in quality assurance.