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Biomedical subjects

H Zusho

Publications and source records attributed to H Zusho.

28 records · Page 2Linked to original sources

Posttraumatic anosmia.

Two hundred twelve patients with traumatic anosmia had been seen at a clinic during the past 16 years. Sequelae of olfactory disorders were observed in 212 (4.2%) of the 5,000 cases seen that involved head and face injuries. The two most severe olfactory disorders were anosmia in 154 (72.6%) cases and hyposmia in 58 (27.4%) cases. The most frequent trauma site was the occipital region followed by the facial and frontal regions. Follow-up investigative results revealed olfactory improvement in eight (14%) of 56 cases. Six (10%) of the 56 cases prompted an aggravation of the olfactory problem. The fragmentation of olfactory nerve fibers appeared to be the most frequent cause of the anosmia after head injury.

Adolescent↗

Diagnosis of olfactory disturbance.

The methods of examination for dysosmia were reported. One thousand four hundred cases of dysosmia were treated in the last 5 years by the following examinations: 1) Olfactory acuity (detected and recognized) threshold test using T & T olfactometer. 2) Blast injection method using an applicator permeated with Alinamin solution. 3) Intravenous olfaction test using Alinamin solution. 4) Endoscopic observation of olfactory mucosa using an endoscope. The parts of lesions were diagnosed and various treatments were selected based on the results of these examinations. Nose drops of adrenocortical hormone were mainly used, while medications of peripheral vasodilator or medications for reducing of the mucosa were used in some cases. Many cases were effectively improved by the nose drops of adrenocortical hormone in Japanese patients. More than 70% of total cases were improved by these treatments.

Adrenocorticotropic Hormone↗

High-resolution MR imaging of the inner ear: findings in Menière's disease.

Symptoms in Menière's disease are characterized by hydrops of the endolymphatic system with recurrent rupture of the membranous labyrinth. The primary cause of the increased endolymphatic volume appears to be an imbalance between secretion and resorption of the endolymph which may be due to an obstruction of the membranous endolymphatic duct and sac, located in the vestibular aqueduct. The membranous endolymphatic duct and sac are not expected to be visualized using conventional tomography and high-resolution computed tomography (HR-CT), whereas, these are identified with high resolution MRI (HR-MRI). By HR-MRI, we proposed to demonstrate morphological alternation in 12 patients with Menière's disease, this group was compared with a group of 20 healthy subjects. The degree of visualization on HR-MRI of the membranous endolymphatic duct and sac running through the vestibular aqueduct in the bony canal was assessed. There was a distinct decrease in visualization of the membranous endolymphatic duct and sac in the Menière's group. The results confirm the value of the HR-MRI technique to identify an anatomical abnormality, which is directly correlated with the lesion in cases of unilateral Menière's disease.

Adult↗