Search PubMed⌕ Search

Biomedical subjects

H Zincke

Publications and source records attributed to H Zincke.

At least 271 records · Page 15Linked to original sources

Intestinal perforation due to fecal impaction after renal transplantation.

Three renal allograft recipients suffered major intestinal complications shortly after the operation. Identification of diverticular disease, adequate preoperative bowel preparation, avoidance of excessive amounts of non-absorbable antacids, early ambulation, and periodic laxatives and stool softeners can prevent these complications. Surgical management includes careful inspection for additional perforations, resection and colostomy, and continuous peritoneal lavage.

Adult↗

Significance of urinary cytology in the early detection of transitional cell cancer of the upper urinary tract.

Cytologic study of urine from 100 patients with transitional cell cancer of the upper urinary tract revealed that findings on the voided and catheterized specimens correlated well with grade and stage of the tumor. However, there was a significantly greater positive yield with urine specimens obtained by ureteral catheterization than by voiding. Consequently, because concomitant bladder tumors, diagnosed or not, can give questionable positive results ureteral catheterization specimens should be used for cytologic study.

Aged↗

Ureterocalicostomy: an alternative to nephrectomy.

Ureterocalicostomy is a procedure with limited indications but with important application in the infrequent patient in whom the more desirable methods of creating unobstructed ureteropelvic drainage cannot be used. Three children are described in whom successful ureterocalicostomy was performed. The most common condition in which ureterocalicostomy has been useful is in the obstructed and scarred, intrarenal pelvis in which a classic type of ureteropyelostomy is not possible. The most important technicalconsideration seems to be sufficient amputation of the lower pole renal cortex in order to free the ureterocaliceal anastomosis from the surrounding cortical tissue. The 3 cases illustrate the difficult situations in which ureterocalicostomy may be indicated and the value of this procedure in preserving maximal renal function in children.

Acute Kidney Injury↗

Critical review of the use of carotid bovine grafts for hemodialysis.

Review of experience at the Mayo Clinic with carotid bovine grafts in patients who undergo hemodialysis with a follow-up of of as long as 28 months revealed that the graft provides vascular access for hemodialysis when other vascular access sources have been exhausted. The graft is particularly helpful in the diabetic patient whose peripheral arteries have inadequate flow. The location in the thigh seems to be preferable to the forearm location. Clean puncture technique is important because infections usually mean graft loss and possibly severe complications, for example, hemorrhage or septicemia.

Adult↗

The role of denervation in renal transplantation on renal function in the dog.

The role of denervation in renal transplantation on renal function in the dog was assessed in a controlled study. There was no significant difference between innervated and denervated kidney with regard to effective renal plasma flow, glomerular filtration rate, and urinary potassium excretion. However, urinary sodium excretion was elevated, and a significant increase in urinary bicarbonate excretion was observed in the in situ denervated or autotransplanted kidney compared with the innervated control kidney. Denervation rather than either tubular damage from the transplantation procedure or a decreased glomerular filtration rate probably is responsible in part for the observed posttransplant urinary sodium and bicarbonate loss and its associated metabolic problems.

Animals↗

The use of procarbazine hydrochloride versus cyclophosphamide in donor pretreatment in cadaveric renal transplantation.

During a prospective study, 13 patients received renal transplants from cadaveric donors whose hearts beat up to the time of their death. These donors were pretreated with cyclophosphamide-methylprednisolone (group A) or methylprednisolone-procarbazine hydrochloride (group B). After a minimum follow-up of 12 months, all grafts in group A but only one graft in group B survived. On the basis of this small experience, the combination of cyclophosphamide and methylprednisolone seems to be superior to that of methylprednisolone and procarbazine hydrochloride in reducing allograft immunogenicity. In order to achieve longer survival of the graft in the recipient, pretreatment with procarbazine hydrochloride has been discontinued. Pretreatment of the potential cadaveric allograft donor with cyclophosphamide and methylprednisolone is being continued at our institution.

Adult↗

Hyperosmolar nonketotic syndrome and steroid diabetes. Occurrence after renal transplantation.

So-called steroid (glucocorticoids) diabetes developed in 11 (5.5%) of 202 patients receiving 216 renal allografts between December 1963 and June 1974. In three of the 11 patients, hyperosmolar nonketotic syndrome was present at diagnosis; all of the three recovered. Eight of the 11 patients survived with functioning allografts, and only one of the eight requires insulin. Hyperglycemia has been detected in most transplant patients tested in the immediate postoperative period. Factors (including stress from surgery and treatment with drugs such as furosemide) predispose to this condition.

Adolescent↗

Experience with lymphoceles after renal transplantation.

Of 215 patients who underwent renal transplantations at the Mayo Clinic, six (2.8 percent) developed perirenal lymphoceles. Diagnosis was made between 5 weeks and 14 months after operation. In all six patients, renal function decreased and eventually a lower quadrant abdominal mass developed. Ipsilateral leg edema, fluid retention, and development of diastolic hypertension should also increase suspicion as to the possibility of lymph collection in the perirenal space. Excretory urography with tomography delineated the lymphocele in each instance; B scan ultrasound may be an additional valuable diagnostic tool. Drainage procedures readily restored normal renal function and, in one instance, drainage also restored the blood pressure to normal. Percutaneous needle aspiration seems to be a temporary measure only, and marsupialization is the preferred definite procedure.

Adult↗