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Biomedical subjects

H Wieland

Publications and source records attributed to H Wieland.

At least 163 records · Page 9Linked to original sources

Isolation and characterization of lipoprotein-X from the pig.

In vitro incubation of pig bile with pig whole serum resulted in the formation of "LP-X like" material migrating towards the cathode on agar-gel electrophoresis. As in all other species studied so far, LP-X occurred also in the serum of bile duct ligated pigs, however, relatively late (48-72h) after the operation. In parallel, alterations of some serum parameters and of the protein-lipid composition of the different lipoporotein fractions were observed. While the electrophoretic behaviour, the protein-lipid and apoprotein composition of pig LP-X were comparable to those found in man, dog and rat, it sedimated in most instances at the density 1.063 g/ml.

Alkaline Phosphatase↗

Improved assessment of plasma lipoprotein patterns. III. Direct measurement of lipoproteins after gel-electrophoresis.

Based on a previously described technique [Clin. Chem. 19, 737 (1973)] of precipitating plasma lipoproteins with polyanions after their electrophoretic separation in gels, a new method is presented for measuring normal plasma lipoproteins densitometrically. The method is fast and easy; the CV for beta-, pre-beta-, and alpha-lipoproteins was less than 5% in one series. Results are linearly related to concentration up to 10 g of total lipoprotein per liter. No unusual equipment is required. Standardization is done with the aid of a commercially available filter. Total plasma cholesterol and cholesterol calculated from quantified lipoprotein fractions were highly (r = 0.963) correlated.

Adult↗

[Vitiliginous depigmentation, liver and splenic lesions and struma due to occupational contact with paratertiary butylphenol--a new systemic occupational disease].

In workers occupied with the production of paratertiary butylphenol, a hepatosplenopathy and a goiter with disorder of the synthesis of thyroid hormone have been observed for the first time besides the well-known vitiliginous depigmentation. It is supposed that paratertiary butylphenol has a systemic effect and causes lesions of various organic systems.

Autoantibodies↗