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Biomedical subjects

H Wendel

Publications and source records attributed to H Wendel.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Clinical studies of the differentiation of macrobullous and rarefying lung diseases].

For the purpose of macrobullous and rarefying pulmonary diseases according to clinical criteria an own examination group of 32 patients with rarefications of the lung parenchyma is analyzed. From the clinical point of view above all two characteristic forms of the course are to be demarcated. On the one hand, vast grotesque tissue defects in the sense of the progressive pulmonary dystrophy with only an insignificant component of bronchitis are found. On the other hand, relatively "small" lesions of the parenchyma are opposite to a distinct obstructive bronchitis. Thus the bronchitis syndrome may in a certain way be helpful differential-diagnostically. The importance of the protease inhibitors for the pathogenesis of such pictures of a disease and the indication of further diagnostic interventions are discussed.

Adult↗
PubMed1982

[Carcinoid of the distal trachea].

We have reported on a 43 years old woman patient, who had fallen ill with an extremely seldom carcinoid tumor arising in the trachea histologically confirmed. Our observations of this woman-patient had been compared with those of 14 patients known from the Anglo-American literature upto 1978. In regard to one French and one Russian collective statistics altogether we come to 24 cases of trachea carcinoids documented in the literature. These are the main symptoms: dyspnea, wheezing, hemoptysis and stridor. Radiation tried at the inoperable patient has proved as ineffective. Today operation seems to be the chosen therapy.

Adult↗
PubMed1981

[Quantitative determination of immunoglobulins in chronic obstructive bronchitis].

In a systematic series of examination the quantitative determination of the immunoglobulin IgG, IgA and IgM in patients with advanced chronic obstructive bronchitis and formation of emphysemas was performed without a spastic component. In the result is to be stated: 1. a highly significant increase of the IgA concentration, 2, a significant decrease of the IgG-concentration, 3. no change of the IgM-concentration. Thus the IgA shows the behaviour known in chronic unspecific inflammation of the bronchial wall. The decrease of IgG proved might be an expression of a general decreased function of the organ due to a chronic hypoxia. The results show that there are apparently no relation between the IgM-concentration in the serum and the chronic obstructive bronchitis.

Adolescent↗
PubMed1981

[Urinary excretion of hydroxyproline in chronic obstructive bronchitis].

The establishment of the hydroxyproline excretion in the urine is done in a normal collective of healthy persons, 68 patients with bronchitis in the compensated and 25 patients with bronchitis in the decompensated stage. The comparison of the mean value by means of the Scheffé-test results in significant differences between the normal collective and the patients with bronchitis in the stage of decompensation. Though an increase of the hydroxyproline excretion in the urine in chronic bronchitis with formation of an emphysema is a prognostically unfavourable prediction, this method cannot be recommended for a broader application in practice. The main reason for this is the danger of an incorrect interpretation on account of insufficient knowledge on the origin of hydroxyproline.

Bronchitis↗
PubMed1981

[Clinical examinations of hemoptysis in chronic inflammatory bronchial diseases].

It is reported on 150 patients who were clinically examined due to expectoration of blood, of whom 103 under went a bronchological diagnostics immediately after hospitalisation. As to the frequencies of causes the tuberculosis occupies the first place, then follows the chronic bronchitis. The frequency of tuberculosis is reached by the chronic unspecific inflammation of the bronchial wall, when the disease groups characterized by symptom - chronic bronchitis, bronchectasia, infected bronchiolectatic honeycomb lung - are united to one collective. The experiences show that by means of endobronchial haemostasis including the tamponade of the bronchus surgical interventions in bleedings of the lung may be avoided, apart form rare exceptions.

Bronchitis↗
PubMed1979

[Pleural asbestosis in dock workers].

During the last three years 29 patients with asbestosis of the pleura were examined. 21 of them were exposed to dust on wharfs as joiners, locksmiths, transport workers, isolators and in other trades. The beginning of the exposition was at least 15 years age, the duration of the exposition was 5 to 25 years. Two bronchial carcinomas and one mesothelioma of the pleura among our patients emphasize the increased risk for malignoma of the patients with asbestosis. For this reasons an early recognition and a regular medical control of the patients as well as a reducthe long time of latency between the beginning of the exposition and the appearance of morphologic changes it is recommended to employ older colleagues in the working places with dust exposition.

Adult↗
PubMed1979

[Benign and semimalignant intrabronchial lung tumors].

From 1961 to 1977 we observed 14 patients with semimalignant and benign intrabronchial tumours. In our own patients only a proportion of 0.8% of all bronchial tumours was of non-malignant or semimalignant origin. It is referred to the symptomatology, diagnostics and therapy of these tumours (7 carcinoids, 1 malignant degenerated carcinoid, 1 metastasizing cylindrome, 2 adenomas, 1 intrabronchial chondroma, 2 neurofibromas). The authors especially deal with the possibility of an endobronchial removal of tumours.

Adolescent↗
PubMed1978

[Relation of radiographic and clinical findings to the pathomorphological changes in Wegener's granulomatosis].

On the basis of two own observations the clinical and radiological routine methods undergo a critical judgment concerning their valency for the diagnosis of Wegener's granulomatosis. The two patients showed the picture of a severe septical disease with high fever and expressed inflammatory changes of the biological reactions. In the first observation a pulmonary round focus and terminally the renal failure, in the second case severe inflammatory changes of the lungs without response to antibiotic therapy were in the foreground. The appearance of this disease as generalized vasculitis is conditioned by the manifold clinical symptomatology and thus renders the diagnostics extraordinarily difficult. The simultaneous affection of the nasopharyngeal space, of the lung and the kidneys may be a guide for the diagnosis. The X-ray findings of the lung are not able to found sufficiently the diagnosis.

Adult↗
PubMed1978

[Clinical studies on the paraneoplastic syndrome in intrathoracic neoplastic diseases].

Two own clinical observations concerning the paraneoplastic syndrome are reported: Gynecomastia and hypertrophic osteoarthropathy. The two symptoms appeared as primary manifestation of a bronchial carcinoma and an intrathoracically situated teratoma. The gynecomastia in an estrogen-producing teratoma of this localisation hitherto has not been described; its classification as paraneoplastic syndrome is established. The value of such individual observations may be that the knowledge of these syndromes should be deepened and thus should be indirectly contribute to the diagnostics of tumours, or even to the early recognition of the tumour.

Adenocarcinoma↗
PubMed1977

[Comparative studies on the firmness of the tracheal wall in goiter and chronic bronchitis].

The changes of the lumen of the trachea according to the tests of Valsalva and Müller in 231 test persons (71 normal persons, 129 struma patients and 31 patients with chronic bronchitis caused by an emphysema) are analyzed in radiologic way. The comparison of the average of the tracheal widths shows significant decreases in the struma patients in relation to the normal collective. On the contrary the tracheal diameters in chronic bronchitis caused by an emphysema shows no statistically evident deviations in comparison with the normal persons. According to calculations of the lumen changes (Valsalva minus Müller) the average in the normal collective is 2.1 mm, in the struma patients 3.4 mm an in chronic bronchitis caused by an emphysema 1.6 mm. The comparison of the statistical average after calculation of these differences results in significant differences only between normal collective and struma patients, too.

Bronchitis↗
PubMed1977

[Mycobacterial infections in internal medicine patients].

It is reported on four own observations of atypical mycobacteriosis, which had been evident within the clinical examinations of a larger mixed number of patients with internal diseases. In three patients pathogenic significance must be ascribed to the proved atypical mycobacteria. All the three had other basic diseases. Only in one patient it appeared as a purely pulmonary form of manifestation. On the basis of a further observation is shown that a single proof of atypical mycobacteria may be regarded only as accidental findings. The clinical symptomatology of this group of diseases is multiform. The differential-diagnostic considerations are usually determined by the basic disease. As apart from this the proof of atypical mycobacteria is difficult, infections with these microorganisms might at present not infrequently remain infrequently. The observation of a disease by mycobacterium xenopi emphasizes that also in this microorganism good chances of success may be given by medicamentous antituberculotic therapy.

Humans↗
PubMed1977

[Pulmonary metastasizing of prostatic carcinoma--source of errors in the ambulatory x-ray examination of lungs].

It is reported on eight patients with a primary carcinoma of the prostatic gland who were admitted to the hospital for clinical clarification of conspicuous pulmonary findings. The radiological findings of a general radiograph of the thorax are multiform and for themselves alone they do not permit an etiological coordination. For this reason the demand can be derived in patients of the adequate age group with tumour symptomatology can also be thought of a carcinoma of the prostatic gland and already during the examination in the outpatient department to carry out a palpatory examination and, if possible, to make a general radiograph of spinal column and pelvis, since in these cases the diagnosis can be made already before admission.

Bronchography↗