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Biomedical subjects

H Weigand

Publications and source records attributed to H Weigand.

At least 37 records · Page 2Linked to original sources

[The problem of anastomosis of the large intestine].

Healing problems following surgery of the colo-rectal junction seem to be due primarily to the blood supply of the anastomosis. Radical resections of the draining lymph system (metastatic road) including the dissection of the inferior mesenteric artery in patients with distal colonic cancer may reduce the blood flow to the oral stump of the anastomosis dramatically. In a retrospective analysis, this kind of resection technique will have a much higher incidence in anastomotic stenosis compared to controls without ligation of the artery. By using the electrical knife versus scalpel or scissors a significant higher damage of the colonic wall in animals and increased healing problems of anastomoses can be expected clinically.

Animals↗

[Intramedullary nailing as secondary intervention following prior use of external fixation].

The external fixation has its clear indications. In some cases, however, healing up of the bone fails to appear. This is caused partly by the gravity of the primary injury, partly by biomechanical reasons. The failure of a perfect fracture healing can require a change of the osteosynthesis procedure. Under certain conditions nailing provides good success. By means of 13 own cases conditions, indications and results of secondary nailing after prior external fixation osteosynthesis will be discussed.

Adult↗

[Necessary stability and biomechanics of fracture healing in external fixation osteosyntheses].

In recent years, many investigators have concerned themselves with improving the construction of the external fixator in order to achieve even greater stability. Clinical observations demonstrate a moderate callus formation and an often considerably delayed fracture healing resulting from such an extreme rigid mounting of the external fixator. This report presents biochemical considerations which indicate that extreme rigidity in the external fixator is not only unnecessary, but may even interfere with fracture healing and the formation of functionally stable bone.

Biomechanical Phenomena↗

[Imaging adrenergic tumours with 131J-meta-benzylguanidine].

Pheochromocytoma scanning using 131J-meta-benzylguanidine was done in one patient with metastasizing paraganglioma, one patient with multiple endocrine neoplasia type IIb. No activity of tumour tissue could be demonstrated in the patient with metastasizing paraganglioma, whereas the pheochromocytoma could be clearly defined in the patient with multiple endocrine neoplasia type IIa. The female with multiple endocrine neoplasia type IIb showed a suspect space-occupying lesion of the left adrenal using computed tomography. Pheochromocytoma could be excluded by 131J-benzylguanidine scanning, selective estimation of catecholamines in adrenal venous blood as well as the glucagon stimulation and clonidine suppression.

Adrenal Gland Neoplasms↗

[Special osteosynthesis-techniques for use on traumatic bone fractures in the region of hip and knee endoprostheses (author's transl)].

Special problems are associated with fractures of bones with implanted endoprostheses. These problems are a result of unusual fracture-types often combined with damage and loosening of parts of the prosthesis, the limited applicability of standard osteosynthesis-procedures and the impaired blood supply of the bone caused by the destruction of the medullary vessels after filling the medullary canal with bone cement. Special operative techniques for the treatment of those problem-fractures are demonstrated such as the extension of the prosthesis by an elastic shaft and the concentric osteosynthesis of an unstable acetabulum by a newly developed implant.

Acetabulum↗

[Experimental investigations of the axial load carrying capacity of the long bones using Steinmann-pins (author's transl)].

This paper reports the results of experimental investigations of the axial load carrying capacity of the long human bones. These investigations were conducted using a commercial high precision materials testing machine. Force-transmission was effected by Steinmann-pins or screws drilled transversely into the various long bones. The measured loading capacities are reported for various sections of the long bones. Their importance in regard to biomechanics, application and dimensioning of compression osteosyntheses by external fixation is discussed in length.

Bone Nails↗

[Biomechanical model for the transmission of dynamic stresses to the long bones by means of an external fixator to stimulate bone formation].

A new biomechanical model using an external fixator is described, which produces physiological dynamic axial stresses on the long bones without causing harmful micromovements at the fracture site. The authors are of the opinion that their model will make it possible to stimulate fracture healing by influencing bone remodelling and tissue differentiation.

Biomechanical Phenomena↗

[Combination injuries of the hip joint including shear fractures of the femoral head].

Shear fractures of the femoral head always occur in association with a dislocation of the hip. In most cases there is a posterior dislocation with a fracture of the inferior aspect of the head. Treatement and long-term results of 23 personal observations are reported. These are, according to Pipkin's classification, divided into six Type-1, four Type-2, five Type-3 and eight Type-4 fracture-dislocations. The poorest results were found in the group of Type-4 injuries, which included six cases of avascular necrosis of the femoral head. In all of these six cases, the femoral head was reduced no sooner than three days after the accident. Specific recommendations for the treatment of Pipkin's four types of combined injuries are made, taking into consideration fragment size, grade of dislocation, and age of the patient.

Femur Head↗

[Early diagnostic imaging of rheumatoid arthritis (RA) (author's transl)].

The respective diagnostic value each of diagnostic radiology and nuclear medicine in the detection of early rheumatoid arthritis is being demonstrated--with close correlation to its clinical presentation and course. Diagnostic radiology is found to be specific and nuclear medicine to be highly sensitive, with the latter giving better diagnostic information at an earlier time about the activity of the disease than the former--including soft tissue technique. Nuclear medicine further--more will be helpful for appropriate timing of diagnostic radiology evaluations of this disease.

Adult↗