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Biomedical subjects

H W Mendenhall

Publications and source records attributed to H W Mendenhall.

18 recordsLinked to original sources
PubMed1989

Birth weight prediction from remote ultrasonographic examination.

Multiple linear regression by the least squares method was used to remodel five existing static equations to permit birth weight estimates from remote ultrasonographic parameters. By incorporating lapse time (examination-to-delivery interval), the new equations can be used to estimate birth weight 0 to 35 days after ultrasonographic examination. For each model, R2 approached 1.0. The generated equations were tested on 167 nonmodel cases. Among the three best equations, 65% to 67% of estimates were within 100 mg/kg birth weight. The mean absolute error ranged from 86 to 91 gm/kg. With a mean lapse time of 16.8 +/- 11 days, the accuracy of birth weight estimates equaled or exceeded that reported for existing static formulas. The accuracy of the estimates was maintained across the entire range of lapse times and birth weights observed. In intrapartum situations when ultrasonography is unavailable or technically difficult, birth weight can be estimated from remote ultrasound parameters.

Birth Weight↗
PubMed1988

Birth weight prediction from remote ultrasound examination.

From 259 cases studied, 245 were selected in which a live-born infant was delivered within 35 days of a complete fetal ultrasound evaluation. Multiple linear regression using the least-squares method enable us to generate an equation that incorporated lapse time (examination-to-birth interval) with the natural logarithm of head circumference, femur length, and abdominal circumference to estimate birth weight. With a lapse time mean of 16 +/- 11 days and a range of zero to 35 days, the generated equation accurately predicted birth weight (R2 = 0.84; P less than or equal to .0001). For all birth weights, the mean error was -15 +/- 306 g, the percent mean error was 0.51 +/- 10.2%, and the mean absolute error of the estimate was 82 g/kg birth weight. This accuracy was maintained across the full range of lapse time observed. For examinations performed within one week of delivery (N = 71), this formula more accurately predicted birth weight than five existing static formulas tested. The accuracy observed during model development was confirmed during testing upon 167 non-model cases. The accurate prediction of birth weight from remote ultrasound data is possible when lapse time is included in the predicting equation. The clinical value of this model is suggested when ultrasound is unavailable or unreliable.

Birth Weight↗
PubMed1983

Abnormal fetal heart rate patterns and percentage of creatine phosphokinase-2.

Eighteen term newborn infants who had been evaluated by internal fetal heart rate (FHR) monitoring were studied to correlate fetal monitor tracings with Apgar scores and serum creatine phosphokinase-1 (CPK2) the myocardium-specific isoenzyme of CPK. The percentage of CPK2 at 30 +/- 6 hours did not correlate significantly with Apgar scores. However, values for the percentage of CPK2 at 30 +/- 6 hours were significantly higher in neonates with abnormal FHR tracings than in those with normal FHR tracings (p less than 0.01). These preliminary data suggest that subtle intrapartum asphyxial injury may be present without adversely affecting Apgar scores.

Apgar Score↗
PubMed1980

The nonstress test: the value of a single acceleration in evaluating the fetus at risk.

Utilization of the nonstress test in the high-risk pregnancy as the sole test for the assessment of fetal welfare is reported. A total of 1,005 tests were performed on 367 patients. A single acceleration in response to fetal movement was deemed sufficient to classify a fetus as reactive, and when present was associated with a corrected perinatal loss of zero. A nonreactive pattern predicted the four stillbirths in the series.

Female↗
PubMed1980

Comparison of auditory versus electronic assessment of antenatal fetal welfare.

The relationship of auscultation of fetal heart rate accelerations to fetal movements, and the comparison of fetal heart rate accelerations with those observed on a fetal monitor, are reported. This auditory nonstress test (NST) was usually confirmed by the electronic fetal monitor. These results indicate that 94.6% of reactive auditory NSTs may allow elimination or reduction of the need for electronic fetal monitoring.

Electronics, Medical↗
PubMed1980

The nonstress test. A preliminary report of a graded classification.

A series of 1,504 antenatal fetal heart rate studies (nonstress tests) in 525 high-risk patients was performed. Accelerations with fetal activity are important. A graded classification of heart rate reactivity was used. There were no antenatal fetal deaths with a reactive pattern. In addition, there was an increasing incidence of intrapartum fetal distress with decreasing fetal cardiac reactivity.

Female↗
PubMed1979

Recurrent endodermal sinus tumor during pregnancy.

A case is reported of a patient who was found to have an endodermal sinus tumor coincident with pregnancy. She maintained a complete clinical response for 12 months after conservative surgery, uterine aspiration, and multiple-agent chemotherapy. Tumor recurrence appeared with a second pregnancy. A healthy infant was delivered despite resumption of chemotherapy. The use of cytotoxic chemotherapy during pregnancy is reviewed.

Adolescent↗