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Biomedical subjects

H W Marks

Publications and source records attributed to H W Marks.

8 recordsLinked to original sources

Management of late extrusions of cochlear implants.

OBJECTIVES: The study aimed to identify the important principles in repairing and preventing delayed cochlear implant extrusions. STUDY DESIGN: The study design was a retrospective, international database review and three case presentations from the authors' local database. SETTING: The study was conducted at a tertiary referral center. PATIENTS: Cochlear Corporation's database of 8,665 implantees in North and South America and Israel was studied. A subset of this database, consisting of 74 patients implanted through the Louisiana State University/Eye, Ear, Nose and Throat (LSU/EENT) project, is analyzed separately and provides the case reports. INTERVENTION: Surgical repair of skin breakdown over the edge of three cochlear implants using a two-layer, pericranial and scalp rotation flap technique was performed. MAIN OUTCOME MEASURES: A functioning cochlear implant with a healthy skin covering was measured. RESULTS: The three LSU/EENT cases reported here used a pericranial flap to repair the capsule of the implant and a large scalp rotation flap to repair the skin defect. A novel pericranial tuck-under technique is especially useful for the Nucleus Mini-22 implant. With this technique, the authors have had a 100% success rate (3 of 3). The basic principles used in the repair and in the initial implant surgery are discussed. CONCLUSIONS: The following conclusions were reached: 1) avoid skin closure lines parallel to the cochlear implant edge that are closer than 1.5 cm from the implant edge; 2) excise enough skin and scar around the dehiscence to achieve principle 1; 3) design a large, well-vascularized anterior- or posterior-based scalp rotation flap to cover this defect; and 4) close the implant capsule defect with a well-vascularized pericranial flap.

Adult↗

New medical/legal interprofessional code for Louisiana undergoing development.[The Medical-Legal Interprofessional Committee. The Louisiana State Medical Society and The Louisiana Bar Association].

The Medical/Legal Interprofessional Committee is a cooperative committee involving representatives of the Louisiana State Medical Society and the Louisiana Bar Association. The committee is currently re-examining its Interprofessional Code and its Advisory Opinion with the intent of combining the documents into a new, concise Code designed to promote cooperation and limit conflicts between the two professions. The precepts of this Code will also guide the Committee in deciding issues and disputes between physicians and attorneys. Reprinted in this issue is the original Interprofessional Code for Physicians and Attorneys of the State of Louisiana and the Advisory Opinion of the Medical/Legal Interprofessional Committee. The Committee encourages all physicians to review these documents and to contribute their thoughts and suggestions on what should be included in the new Code and how the relationships between the two professions can be improved. Please send comments to: Louisiana State Medical Society, Medical/Legal Interprofessional Committee, 3501 N Causeway Blvd, Suite 800, Metairie, LA 70002.

Fees, Medical↗

Cholesterol granuloma of the petrous apex.

Cholesterol granuloma of the petrous apex is caused by a foreign body response to cholesterol crystals. This condition has infrequently been described, but it can prove to be highly destructive. Obstruction of drainage, with failure of ventilation of a normally aerated space and subsequent hemorrhage, yields blood breakdown products which liberate cholesterol. Osteitis, bone erosion, and bone resorption have all been reported, but major bone destruction is rare. It should always be considered by otologists and skull base surgeons when evaluating lesions of the petrous apex. This article reviews the more common causes of primary lesions of the petrous apex, with special emphasis on the clinical findings, pathophysiology, and surgical considerations in cholesterol granuloma. Two pertinent case histories are included.

Adult↗

Glucagon and esophageal meat impaction.

Glucagon is suggested as an alternate method of treatment in difficult cases of esophageal meat impaction. Glucagon has been used in diagnostic roentgenology to facilitate smooth muscle relaxation. We describe its characteristics and mode of action, and we report two cases that emphasize the advantages of glucagon therapy as a primary modality or as an alternative in problem cases.

Esophagus↗

Bone-conduction electrocochleography: clinical applications.

Cases are presented which show the clinical utility of recording an electrocochleographic response to bone-conducted stimuli. The procedure is fraught with problems of acoustic control and artifact generation, but has distinct although limited values in clarifying masking dilemmas in patients with bilateral hearing loss.

Adolescent↗

Isolation and Identification of Canthaxanthin from Micrococcus roseus.

Cooney, J. J. (University of Dayton, Dayton, Ohio), H. W. Marks, Jr., and Anne M. Smith. Isolation and identification of canthaxanthin from Micrococcus roseus. J. Bacteriol. 92:342-345. 1966.-The principal colored carotenoid of Micrococcus roseus was purified by solvent partitioning followed by column and thin-layer chromatography. Absorption spectra, partition coefficients, and infrared spectra suggested that the pigment was a diketo derivative of beta-carotene. The pigment was subjected to reduction, and the reduced pigment was subsequently dehydrated. Spectral data and partition coefficients of these derivatives indicated that the original pigment was canthaxanthin (4',4'-diketo-beta-carotene). The pigment was an all-trans isomer; it does not exist as an ester in M. roseus. Canthaxanthin has not previously been identified as a bacterial pigment.

Journal Article↗