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Biomedical subjects

H W Leibowitz

Publications and source records attributed to H W Leibowitz.

At least 19 recordsLinked to original sources

Age differences in dynamic contrast thresholds.

Contrast thresholds for sinusoidal gratings of 1.5-18 cpd were measured in young (M = 24 years) and older adults (M = 69 years). Thresholds were determined for stationary gratings, and for gratings that traveled along a circular path at 5, 10, and 15 deg/sec. For static gratings, age differences in thresholds were greater for intermediate and higher spatial frequencies. Grating motion increased thresholds for all observers, but older adults exhibited threshold increases at lower target velocities than the young. Age differences in velocity effects were generally greater at intermediate and higher spatial frequencies. Results are discussed in relation to age changes in temporal resolution and smooth pursuit gain.

Adolescent

The effects of visual factors and head orientation on postural steadiness in women 55 to 70 years of age.

This study was designed to establish reference data for the effects of head position and visual conditions on the standing posture of healthy women ages 55 to 70. Center of pressure (CoP) data were analyzed using ANOVA models. Total CoP displacement was 45% greater (significant, p less than .05) when the subjects stood with their heads back and their eyes closed, as compared to standing looking straight ahead. Visual surrounds consisting of vertical visual cues resulted in less postural sway (PS) than surrounds made of horizontal visual cues (significant, p less than .05 for anteroposterior CoP range). Experimentally reduced visual acuity resulted in greater PS, while changes in ambient lighting and spatial frequency of visual cues affected PS minimally. These results suggest that a reduction in the height of shelving, and the provision of high-contrast visual cues and vertical geometric patterns are potential intervention strategies to optimize vestibular sensory input and visual orientational cues for the maintenance of stability during stance.

Aged

Age differences in estimating vehicle velocity.

Automobile accidents among older adults may be related to difficulties in judging the speed of other vehicles. To examine this possibility, 3 groups of observers in the young adult, middle-aged, and older adult age ranges were asked to estimate the velocity of an isolated automobile traveling at 15-50 mph (24-80 kph). Across all age groups, perceived and actual velocity were related by a power function with an exponent of 1.36. Age was significantly and positively correlated with intercepts, but negatively correlated with exponents; that is, older observers showed less sensitivity to changes in actual velocity. Results bear on the issues of ontogenetic changes in accident involvement and sensitivity to motion.

Acceleration

The influence of visual factors on fall-related kinematic variables during stair descent by older women.

Despite the documented health hazards associated with stair descent, the mechanisms of falling on stairs remain relatively unexamined. The objectives of this study were to define kinematic variables that could be used to describe foot-stair spatial relationships during the mid-stair phase of stair descent, and to investigate the effects of various visual and environmental conditions on those variables in a group of 36 healthy women between the ages of 55 and 70. Foot clearance and foot placement were measured through high-speed film analysis. Clearance between the foot and the stair during swing phase was small under all visual conditions. Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not. The kinematic variables used in this experiment may be helpful in future studies to assess the results of interventions aimed at reducing the frequency of falls on stairs.

Accidental Falls

Effect of luminance on the relation between accommodation and convergence.

When luminance is lowered, both vergence and accommodation tend to shift toward different and individually characteristic resting postures, commonly referred to as dark-vergence and dark-focus. In order to determine the luminance level at which these two mechanisms correspond to a target distance, subjects viewed a light spot 0.4 mm in diameter, corresponding to 1.4 to 2.7 min arc, located at the individually determined dark-focus position. As the luminance of a binocularly viewed spot increased, accommodation did not change significantly from the target distance. However, fusional vergence gradually shifted from the dark-vergence to the target position. The critical luminance level at which the 2 responses were coupled for the 12 observers ranged from 0.01 to 0.45 cd/m2, with distinct individual differences. In a second experiment, the target was positioned at distances different from the dark-focus and luminance was set at 0.5 and 1.0 log unit higher than the subject's critical luminance level. At lower luminance levels, mononuclear focus tended to remain at the individual dark-focus, whereas the binocular focus tended to correspond to the target distance. These differences can be attributed to vergence accommodation. Previous studies on night myopia reported that a negative correction based on one-half of the individual dark focus was superior to a full dark-focus correction. The present results suggest that this difference is due to vergence accommodation and that the optimum correction for night myopia depends, in part, on the critical luminance level for activation of fusional vergence.

Accommodation, Ocular

Bandwidth of the contrast sensitivity function as an index of spatial vision with application to refraction.

The contrast sensitivity function (CSF), although containing more information than traditional measures of acuity, has found difficulty gaining clinical acceptance. The hesitancy of clinicians to adopt the CSF stems, in part, from the fact that it is not as readily interpreted as is acuity. In order to facilitate such interpretation, five indices of spatial vision which are derivable from the CSF were examined in a sample of 287 persons aged 5 to 85 years. All indices were found to be both age-sensitive and strongly related to each other, but bandwidth of the CSF was chosen as a practical index for clinical settings. In a second study, acuity and CSF bandwidth were measured under 0 to +/- 1 D optical blur. It was found that the correction providing best acuity also maximized CSF bandwidth, and that bandwidth was more sensitive to optical blur than was acuity. Results support the assertion that CSF bandwidth is a readily interpreted index of spatial vision that can be measured efficiently within the context of clinical refraction.

Adolescent

The relation of vergence effort to reports of visual fatigue following prolonged near work.

Two experiments examined the link between vergence effort and subjective reports of visual fatigue following prolonged near work. In Experiment 1, dark vergence and reports of visual fatigue symptoms associated with computer use were measured in 104 persons. Dark vergence was significantly correlated with four of six symptoms of visual fatigue. In Experiment 2, 16 subjects who exhibited clear "Heuer effects" (systematic gaze-related changes in dark vergence) read from a video display terminal (VDT) at a distance of 20 cm for 60 min under two gaze elevation conditions: 20 deg above and 20 deg below a baseline gaze elevation. This manipulation was designed to vary the amount of vergence effort required to fixate the VDT. Results indicate a positive relation between vergence effort and visual fatigue both within and between subjects, and that prolonged near work leads to decreased vergence accuracy at far distances. Implications for VDT workstation design are discussed.

Adolescent

The effects of fixation and restricted visual field on vection-induced motion sickness.

Approximately 60% of healthy human subjects experience motion sickness when exposed to a rotating optokinetic drum. The purpose of the present study was to determine the effects of certain visual factors on susceptibility to motion sickness. Vection data (illusory self-motion), horizontal eye movement recordings, subjective motion sickness report, and a measure of gastric myoelectric activity (electrogastrogram, EGG) were obtained from 45 subjects, who were randomly divided into the following three groups: a control group that observed the entire visual field with no fixation, a group that fixated on a central target, and a third group that had a visual field restricted to 15 degrees. The experimental session was divided into the following three 12-min periods: baseline, drum rotation, and recovery. The results showed that fixation greatly reduced nystagmus and slightly reduced vection. The restricted visual field slightly reduced nystagmus and greatly reduced vection. Both of these manipulations significantly reduced symptoms of motion sickness and tachyarrhythmia, the abnormal gastric myoelectric activity that usually accompanies nausea.

Electromyography

Age differences in peripheral refractive error.

Refractive error was measured at 0 degrees to 40 degrees temporal to fixation in 10 young adults (M age = 26 years) and 10 older adults (M age = 63 years). Older adults exhibited a greater amount of sphere (i.e., overall) error, but no more so in the periphery than in the fovea. Although age differences were small, younger adults were found to exhibit more peripheral astigmatism than the older adults. Discrepancies between obtained results and those of Millodot (1985) may be attributed to the relationship between peripheral astigmatism and presenting refractive status. Alternatively, a two-mechanism model of age-related change in lens curvature is capable of accounting for across-study outcome differences. Recommendations are made concerning optimal viewing conditions for the study of age differences in visual perceptual processes.

Adult

Visual performance on CRT screens and hard-copy displays.

Three experiments examined the effect of hard-copy print and CRT screens of different resolution/addressability ratios (RAR) on accommodation and visual search performance. Three different display modes were generated with an IBM personal computer and a Princeton Graphics Terminal: capital letters in high-RAR mode, capital letters in low-RAR mode, and capital letters in high-RAR mode programmed to simulate the low-RAR mode. Same-sized letters were also presented on hard-copy print. Experiment 1 demonstrated that accommodation to hardcopy print and high-RAR screens was more accurate than to low-RAR screens. In Experiment 2 the spatial frequency channels activated by each display were evaluated by measuring the effect of display adaptation on the contrast-sensitivity function. The results suggested that high-RAR screens and hard-copy print activated higher-frequency channels than did low-RAR screens. In Experiment 3 significantly better visual search performance was obtained for high-RAR screens and for hard-copy print than for low-RAR screens. It was concluded that screen RAR is an important variable to consider in the design of CRTs.

Accommodation, Ocular

Age differences in Vistech near contrast sensitivity.

Contrast sensitivity was measured at near using the Vistech 6000 Contrast Test System (VCTS) in 287 persons aged 4 to 87 years. Obtained data compared well with those previously reported for the Vistech charts. Results indicate an age-related loss in sensitivity to intermediate and higher spatial frequencies. This is consistent with the age trends observed using other methods for measuring contrast sensitivity functions (CSFs). However, the Vistech charts yield contrast sensitivity values which are lower than those obtained previously with the Nicolet system. These between-method differences are greatest at lower spatial frequencies, and are attributed to the small number of grating cycles in the Vistech charts. The data are used to develop provisional age norms for the Vistech charts which allow the assessment of an individual's performance relative to their age cohort. Recommendations for use and future development of the Vistech charts are also given.

Adolescent

Correction of empty-field myopia on the basis of the dark-focus of accommodation.

The influence of negative spherical corrections on the detection of a small increment flash presented in a uniform field or Ganzfeld were determined. The range investigated included each observer's normal correction as well as values based on the focus assumed by each observer in total darkness (dark-focus of accomodation). A correction equivalent to the dark-focus resulted in maximum sensitivity. The results suggest a convenient technique for the determination of optimal correction for empty-field viewing conditions.

Accommodation, Ocular

New evidence for the intermediate position of relaxed accommodation.

Experimental evidence is presented that the focus of the eye tends to return passively to an individually characteristic intermediate resting position or dark-focus whenever (1) the stimulus to accommodation is degraded or (2) when the quality of the image is independent of focus. Based on measurements of the dark-focus with a laser optometer, it is possible to predict the magnitude of night, empty field, and instrument myopia on an individual basis. The role of the intermediate dark-focus as a factor in accommodation also provides an explanation for the paradoxical variation of visual acuity with observation distance. Applications to night myopia and night driving are described, and implications for clinical practice are discussed.

Accommodation, Ocular

The effect of refractive error on size constancy and shape constancy.

The effect of refractive error was determined for both size constancy and shape constancy. Although an error of 1.5 diopters reduces shape constancy, 3.0 diopters of blur had no effect on size constancy. The results are discussed in terms of the multiple mechanisms subserving the perceptual constancies. The importance of cues from the peripheral visual fields for size constancy and the role of foveally mediated texture and stereopsis cues for shape constancy are emphasized.

Adult

Human conjunctivitis. I. Diagnostic evaluation.

One hundred forty-three patients (207 eyes) with conjunctivitis or blepharoconjunctivitis were studied. Attempts were made to establish an etiologic diagnosis by clinical and laboratory methods. The etiologic diagnosis that was made on the basis of the initial clinical examination correlated poorly with the results of standard laboratory tests. Conversely, the standard laboratory evaluation failed to establish a definitive diagnosis in the majority of cases. These findings suggest that the diagnostic dogmatism prevalent in conjunctivitis is unwarranted. Morphologic signs and routine laboratory tests leave us without a verified etiologic diagnosis in a substantial number of cases.¿

Acute Disease