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Biomedical subjects

H W Johnson

Publications and source records attributed to H W Johnson.

53 records · Page 3Linked to original sources

Idiopathic retroperitoneal fibrosis in children.

A case of idiopathic retroperitoneal fibrosis in an 11-year-old boy is presented. A review of 7 previous case reports revealed that there was no characteristic presentation in this disease process and that the diagnosis usually is suspected on an excretory urogram. The treatment is primarily surgical but corticosteroids may be helpful in selective cases.

Child↗

Experiences with priapism.

During a 10-year period 11 cases of priapism were treated with a saphenocavernous bypass. Uniformly good functional results were obtained if the procedure was done within 36 hours of the commencement of priapism. Prior aspiration and irrigation appear to lengthen this interval. The formation of temporary cavernovenous communication with the superficial venous system of the penis by aspiration and irrigation with large needles is demonstrated and is postulated as a mechanism by which this method of treatment alone is occasionally successful. Persisting graft patency has been associated with impotence. If erection does not occur within 3 months of the saphenous bypass the shunt should be ligated.

Anesthesia, Epidural↗

A linguistic and cognitive persepctive on retardation.

The idea of critical readiness periods for both language learning and cognitive development was reviewed and related to mental subnormalities. A basic model of a synthesized theory of language and cognition was presented, and a theoretical "Basal Person" was constructed to illustrate a new perspective on retardation. The general conclusions reached were that (a) the basal person represents the lowest normal level of cognitive linguistic development, and (b) retardation can be defined in terms of impeded or disrupted development during critical readiness periods.

Age Factors↗

Thermostability of antigens associated with serotype of Rhizobium japonicum.

The antigens associated with serologically distinct strains of Rhizobium japonicum were found to differ in heat sensitivity. Cell preparations from 4 out of 12 strains retained agglutinability, and 1 out of 5 retained antigenicity after they were heated to 120 C. Antigenicity was reduced in most strains after heating to 100 C for 30 min, but agglutinability was not affected by this treatment. This suggests that the antigens are protein-polysaccharide-lipid complexes described for O-type antigens. Cells of strain 46, however, retained both agglutinability and antigenicity after heating to 120 C for 1 hr, and thus a protein in its structure seems improbable. Antigens associated with bacteria from soybean nodules responded to heat treatment in essentially the same manner as those from the same strain grown in nutrient broth. Certain serotypes showed a tendency to agglutinate spontaneously. A heat treatment of 100 C for 30 min, to remove nodule debris and destroy certain blocking antigens, did not interfere with the agglutination reaction. Live cells induced antiserum in rabbit to a higher titer than did heat-treated cells.

Agglutination Tests↗