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Biomedical subjects

H W Gray

Publications and source records attributed to H W Gray.

At least 73 records · Page 4Linked to original sources

Clinical value of delayed thallium-201 myocardial imaging in suspected acute myocardial infarction.

Fifty patients with acute chest pain had thallium-201 myocardial imaging performed three to six days after emergency admission to hospital. The image was abnormal in 20 out of 22 patients with acute transmural myocardial infarcts but in only 1 of 5 with acute subendocardial infarcts. Indistinguishable scan abnormalities caused by old infarcts were seen in 7 patients, and caused by myocardial ischaemia in 1 patient. A single thallium-201 myocardial scan some days after the onset of symptoms appears to be of little value in the clinical assessment of patients with suspected acute myocardial infarction.

Acute Disease↗

A quantitative study of leukocyte cohesion: effects of divalent cations and pH.

Leukocyte cell-to-cell adhesion was studied with a cell monolayer technique. The amount of protein retained on the coverslip reflected the number of adhering cells. When polymorphonuclear leukocytes were suspended in a balanced salt solution at neutral pH containing no bivalent cations, they adhered to the glass surface but not to each other. Magnesium or calcium at concentrations above 1 mM caused cell-to-cell adhesion. Stannous and chromate ions had no effect on leukocyte cell-to-cell adhesion. Acid pH also induced leukocyte aggregation. This last effect could be reversed by washing the cells with a balanced salt solution at neutral pH, but it could not be reversed by alcohol.

Calcium↗