Search PubMed⌕ Search

Biomedical subjects

H W Ferguson

Publications and source records attributed to H W Ferguson.

61 records · Page 4Linked to original sources

The pathology of systemic iridoviral disease in fish.

Iridoviruses have been associated with severe disease and economic loss in farmed food fish and ornamental fish, with mortality often reported to reach 50% or more. In the present study, three tropical marine food fish species and four tropical freshwater ornamental fish species with systemic iridovirus infections were examined histopathologically and ultrastructurally. Light microscopy consistently revealed pale to intensely basophilic hypertrophied virus-infected cells in spleen, kidney and intestine from all seven species. Ultrastructural examination showed changes in the vascular endothelium overlying hypertrophied virus-infected cells suggestive of pressure necrosis. Viral isolation was improved by the use of fibroblastic cell lines. This, together with the sub-endothelial location of infected cells in all infected species examined, suggests that systemic iridoviruses are mesotheliotropic.

Animals↗

Odontogenic keratocyst.

Odontogenic keratocysts comprise approximately eight percent of all jaw cysts and have a significant recurrence rate. Following a review of the literature, the treatment of two patients with such cysts is described.

Adolescent↗