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Biomedical subjects

H Unger

Publications and source records attributed to H Unger.

At least 19 recordsLinked to original sources
PubMed1996

Early visual recovery after excimer laser surgery for myopia: the Melbourne OmniMed results.

BACKGROUND AND OBJECTIVE: Although the refractive outcome can change for months after photorefractive keratectomy (PRK), early visual results are of particular importance during pre-operative counseling of prospective PRK candidates. The expected vision in the first week post-operatively, following 6.0 mm or larger zone photoablation for myopia with the Summit OmniMed (Apex) laser, has not been analyzed in the literature to date. This study is intended to provide an indication of the early visual acuity that may be experienced by a patient undergoing PRK for myopia. PATIENTS AND METHODS: The visual acuity recorded for 123 consecutive patients, (79 low myopes [-1.00 to -5.90 diopters (D)], 44 high extreme myopes [-6.00 to -19.00 D]), one week after they had undergone PRK, was analyzed. All patients included in the study had undergone PRK with the Summit OmniMed (Apex) excimer laser, leaving small degrees of astigmatism uncorrected. RESULTS: One week after PRK, uncorrected visual acuity was better for low myopes than high myopes. Of the low myopes, 83.0% were 20/40 or better compared with high myopes of whom 61.4% were 20/40 or better. CONCLUSION: Patients can be counseled that functional vision will be present in the period immediately after re-epithelialization.

Adult↗
PubMed1990

Dopamine infusion in patients with hepatic encephalopathy: plasma levels and haemodynamic changes.

During a constant infusion of dopamine (DA 4.5 micrograms/kg/min), the plasma levels of DA reached at 30 min of infusion were 81 +/- 6.9 ng/ml and 71.6 +/- 14.8 ng/ml in patients with hepatic encephalopathy (HE) and control patients, respectively. In both groups of patients, the plasma levels of DA did not change between 30 and 60 min of continuous DA infusion. The DA infusion was associated with an increase of arterial blood pressure, heart rate and cardiac index. In the patients with HE, the increase in cardiac index was directly correlated with the plasma level of DA (r = 0.843, p less than 0.01). The present results clearly demonstrate that in HE circulating DA does not accumulate during continuous infusion of DA. They further provide evidence that the increase in circulating catecholamines in HE reflects increased release from the sympatho-adrenal system.

Adult↗
PubMed1989

Malignant endovascular papillary angioendothelioma (Dabska tumor). A case report and review of the literature.

Malignant endovascular papillary angioendothelioma is a rare vascular tumor of childhood that was first defined by Dabska in 1969. Microscopically, this tumor is composed of anastomosing vascular channels, some of which contain papillary projections or tuft-like structures sometimes resembling renal glomeruli. Although cases have been reported with metastases to regional lymph nodes, the long term prognosis for patients with these tumors is generally good. We have studied this tumor by light and electron microscopy as well as immunohistochemical techniques in a 10-year-old boy. A review of the literature on this rare entity is presented.

Back↗
PubMed1983

Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption.

The action of watery rat gut extracts on glucose-induced insulin release in anaesthetized rats was examined before and after removal of GIP by immunoadsorption. Infusions of GIP-containing rat gut extracts nearly doubled the insulin release induced by intravenous glucose (1 g X kg -1 X h -1). Peak insulin secretion was 98 +/- 11 mU/l (mean +/- SEM) after intravenous glucose and increased to 178 +/- 16 mU/l following infusion of glucose plus gut extract (p less than 0.005). After injection of GIP antiserum in sufficient amounts to neutralize the GIP activity in the gut extract preparation, the additional insulin release due to the gut extract was reduced by only 30%. After complete removal of GIP from gut extracts by immuno-absorption, more than 50% of the incretin effect remained. These data suggest that the insulinotropic activity of rat gut extracts can only be partially related to GIP. The existence of additional insulinotropic gut factors which may also be released following oral glucose is postulated.

Animals↗
PubMed1982

[Self-control of blood sugar (author's transl)].

Nine well-trained insulin-dependent diabetics checked their blood sugar using a test strip (Haemo-Glukotest 20-800) and three reflectometers (Reflomat, Dextrometer, Glucosemeter) in order to compare the accuracy of the three instruments with that of the test strip. 227 single checks were carried out, and the blood sugar was checked by means of the hexokinase method. The correlation of the four methods with the hexokinase method was comparable: Reflomat r = 0.95, Dextrometer r = 0.94, Haemo-Glukotest 20-800 r = 0.93, Glucosemeter r = 0.91. Classification of the results into various measuring ranges yielded a comparable accuracy of all four methods between 40 and 250 mg/dl; above 250 mg/dl, there was a considerable decrease in accuracy even of the reflectometers. Hence, the reflectometers do not offer any significant advantages over the visual Haemo-Glukotest 20-800 readings as far as self-control of blood sugar by the diabetic is concerned.

Adult↗
PubMed1980

[Self-control of blood sugar with a new blood sugar test strip (author's transl)].

Blood sugar self-control was assessed in 20 in-patients using a new blood sugar test strip, Haemo-Glukotest 20--800. Comparative estimations of 445 strip tests with values obtained by the hexokinase method showed good correlations particularly in the low range below the renal threshold. Nearly 70% of measurements were assessed correctly in this range. Mean deviations of test strip results from the corresponding laboratory value were 0.61 to 0.89 mmol/l (11--16 mg/dl). Haemo-Glukotest 20--800 is thus well suited for blood glucose self-control particularly in the range below the renal threshold. In a survey most patients estimated the importance of blood sugar to be more than that of urinary sugar.

Activities of Daily Living↗
PubMed1980

[Changes in shape and plasticity of preserved erythrocytes].

The present study is concerned with alterations of erythrocyte shape and deformability during banking of ACD-AG blood samples. Highly diluted blood plasma suspensions of erythrocytes previously stored for 1 and 43 days, respectively, were employed for a) the microscopic evaluation of cell shapes, and b) measurement of the negative pressure pt essential for a cell's complete transit of a cylindrical micropipette 3.2 micrometers in diameter. Each of the blood samples was studied in an air equilibrated state either prior and following the fractionation of light and heavy cells. The classification of cell shapes was accomplished by a particular index. The findings are in accord with the banking related transformation of erythrocytes as known from recent studies. Although, exept of spheroechinocytes and spherocytes, a significant decline of deformability of stored red cells was found only in the case of discocytes and type 3 echinocytes, all types of heavy erythrocytes were shown less deformable in comparison with light cells equally banked for 43 days. The relation between our pt values and published data is discussed, and a crude estimate of the trapping time of the most rigid cells by the spleen after retransfusion is presented.

Blood Preservation↗
PubMed1980

Correspondence of brain and rectal temperatures of guinea pigs in helium environments.

Brain and rectal temperatures were measured in guinea pigs exposed to helium-oxygen environments at pressures as high as 50 bars. Very high correlations (r = .856, P less than 0.001) between the two values were observed, with an average difference of 0.47 degrees C (computed SD = 0.31). Brain temperature was usually higher than rectal. At a given ambient temperature, heat loss at 50 bars was more rapid than at 20 bars, which supports existing data for lower pressures. At 50 bars, normal equilibrium temperatures (approximately equal to 39 degrees C) could be maintained only if ambient temperature was in the vicinity of 35 degrees C. Lower ambient temperatures resulted in lower equilibrium temperatures. Between 33 and 39 degrees C, brain temperature can be predicted from rectal temperature, with an error of about 0.5 degree C.

Animals↗
PubMed1979

The role of Pityrosporum pachydermatis in otitis externa of dogs: evaluation of a treatment with miconazole.

The bacterial and mycotic flora were assessed in 158 ears of dogs with otitis externa and in 101 ears of healthy control dogs. Pityrosporum pachydermatis occurred in 57 per cent of ears with otitis externa and in 17 per cent of clinically healthy ears. Staphylococci and Pseudomonas aeruginosa were the predominant bacteria in otitic ears, micrococci and Bacillus spp were the most frequent isolates from clinically healthy ears. P pachydermatis, Ps aeruginosa and Candida tropicalis occurred in monoculture in a significant number of mainly chronic cases of otitis externa. A combination preparation, containing miconazole, polymyzin B and prednisolone, was highly effective in controlling the clinical signs of otitis externa and eliminating flora from the affected ears. The data presented suggest that yeasts, and especially P pachydermatis, may be significant pathogens in otitis externa and that antimycotic treatment is an essential part of the treatment of otitis externa in dogs.

Animals↗