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Biomedical subjects

H Toyoshima

Publications and source records attributed to H Toyoshima.

197 records · Page 11Linked to original sources
PubMed1974

Sequential change in the different of potential distribution between a normal subject and simulated torso model.

Isopotential map was obtained every 3 msec after the onset of ventricular activation from 85 unipolar lead ECGs of a normal subject (Measured map) and similar map at the corresponding instant (Simulated map) was also obtained by means of mathematical calculation under the assumption that the cardiac electromotive force can be represented by a single electric dipole fixed at the heart center. These 2 maps were quantitatively compared and difference was delineated on a map (Difference map). Although, in major aspect, there was a fairly good agreement between Measured and Simulated maps during early stages of ventricular activation, a remarkable difference of potential distribution began to appear between them around the time of occurrence of epicardial breakthrough of the ventricular activation front. From that t me on, it became impossible to represent the cardiac electromotive force into 2 or more electric dipoles in Difference map. Difference maps around the instant of epicardial breakthrough of the ventricular activation were supposed to be helpful for the estimation of the spread of ventricular activation.

Action Potentials↗
PubMed1967

[Cardiospasm].

Explore the source record for details and available documents.

Adult↗
PubMedDate not supplied

The impact of side effects on hypertension management: a Japanese survey.

The purpose of this study was to assess medication compliance and to document side effects among a large number of Japanese patients receiving antihypertensive treatment. A total of 6289 patients being treated for hypertension returned completed questionnaires about their current blood pressure, therapy, side effects, and compliance with physicians' instructions. In addition, 4417 physicians returned completed questionnaires about their prescribing practices, side effects experienced by patients, and patient compliance. The antihypertensive agents they most often prescribed were calcium channel blockers, followed by angiotensin-converting enzyme inhibitors, beta-blockers, and diuretics. The proportion of patients who had well-controlled blood pressure, defined as systolic blood pressure < 160 mm Hg and diastolic blood pressure < 95 mm Hg, was similar regardless of the class of antihypertensive agent prescribed. Forty-nine percent of the patients with well-controlled blood pressure reported having at least one side effect while taking their current antihypertensive therapy, whereas a significantly greater percentage of patients (61%) with poorly controlled blood pressure reported side effects. Patients whose blood pressure was poorly controlled tended to have a higher incidence of most side effects than did those with well-controlled blood pressure. Also, the rate of intentional noncompliance was significantly higher in the group with poorly controlled blood pressure. In addition, the rate of noncompliance increased with the number of side effects reported. Although the causal relationship between side effects and non-compliance cannot be determined from this study, further investigation is warranted to better understand the impact these factors may have on overall cardiovascular morbidity and mortality.

Aged↗
PubMedDate not supplied

Influence of arterial partial pressure of carbon dioxide on cerebral MRA in normal volunteers.

OBJECTIVE: Signal intensity of MR angiography (MRA) is influenced by the physiological factors of flowing blood in the vessels. We examined whether MRA can detect a cerebral hemodynamic change induced by reducing or elevating the arterial partial pressure of carbon dioxide (PaCO2). MATERIALS AND METHODS: Cerebral MRA was performed in six normal volunteers, each having three measurements during hyperventilation, normal breathing, and 7% CO2 inhalation. The MRA data were obtained by a 0.5 T wholebody scanner and a time-of-flight technique of three-dimensional GE imaging. In addition to the visual inspection, the signal intensity and the lengths of the middle cerebral artery (MCA) and posterior cerebral artery (PCA) were estimated in relation to PaCO2. RESULTS: The MRA appearances of major cerebral arteries were remarkably different depending on the breathing conditions. There was significant difference in the mean signal intensity (p < 0.01) and the mean length (p < 0.01) of the MCA and PCA between the hyperventilation and normal breathing trials. CONCLUSION: The MRA signal was sensitive to the changes in PaCO2 level of flowing blood. This phenomenon may result from changes in the velocity of blood flow in major cerebral arteries.

Administration, Inhalation↗
PubMedDate not supplied

Extrahepatic portal obstruction with intestinal malrotation: a case report.

We report the case of a 20-year-old woman with extrahepatic portal obstruction, anomalous branching of the celiac artery, and intestinal malrotation with duodenal dysgenesis. The patient had no history of neonatal event and had normal liver function. The combination of these abnormalities, rarely reported in the literature, suggests that the extrahepatic portal obstruction in this case might be congenital in origin.

Adult↗
PubMedDate not supplied

Biloma following transcatheter oily chemoembolization.

Hepatic biloma (bile cyst) developed in a patient after transcatheter oily chemoembolization (TOCE) with Lipiodol for hepatocellular carcinoma. The patient was treated conservatively and underwent the next TOCE uneventfully. An inappropriately large dose of Lipiodol, anticancer agent, and Gelfoam can induce biloma; however, it is not reasonable to abstain from TOCE for hepatocellular carcinoma in fear of biloma.

Bile↗
PubMedDate not supplied

Spectroscopic imaging by dephasing amplitude changing (SIDAC).

A technique for spectroscopic imaging based on a new concept of dual encoding (i.e., both phase and frequency encoding) of position along the direction of the read-out gradient is proposed. The phase encoding is produced by changing the amplitude of the dephasing gradient as in conventional phase encoding. High-resolution spectroscopic images of a normal human thigh obtained by a 2.0 Tesla whole body MR imaging system are presented.

Humans↗