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Biomedical subjects

H Toshima

Publications and source records attributed to H Toshima.

At least 199 records · Page 11Linked to original sources
PubMed1978

Isolated stenosis of the pulmonary artery branches--an autopsy case with review of the literatures.

A necropsy of a 21-year-old male with isolated stenosis of the pulmonary artery was presented. The pulmonary artery branches showed various fibrous thickening including atheromata and mural thrombi. Those findings appeared mostly in elastic and large muscular pulmonary arteries as well as in medium sized arteries, while the small arteries and arterioles remained in slight changes. Systemic large elastic arteries seemed to be small and showed atheromatous lesions similar to those of the main pulmonary arteries. Moreover, eight autopsy cases with pulmonary artery stenosis from the literature were shortly reviewed and some pathological findings as an aid for angiographic cardiovascular studies were discussed.

Adolescent↗
PubMed1977

Noonan syndrome with hypertrophic obstructive cardiomyopathy.

A case of a 20 years old female who had Noonan syndrome associated with obstructive cardiomyopathy was presented. It is well known that Noonan syndrome is frequently complicated with cardiac anomaly, and although no autopsies were performed two cases have been diagnosed clinically as Noonan syndrome accompanied with idiopathic cardiomyopathy in our country. The present case would be the first autopsied case in Japan of Noonan syndrome associated with idiopathic obstructive cardiomyopathy.

Adult↗
PubMed1977

Preoperative evaluation of the structural lesion of the mitral valve by M-mode scan echocardiography.

M-mode scan echocardiographic studies of the mitral valve were performed in order to investigate structural architecture of the diseased mitral valve. Structural lesion of the mitral valve was assessed by the echo-pattern change, an increase in number or thickness of the diastolic mitral echo complex. The echo-pattern was classified into 4 grades according to number or thickness of the mitral echoes. The echo-pattern grade correlated with the degree of the structural lesion of 21 surgically excised mitral valves. Clinically, the echo-pattern grade was compared with subsequent operative procedure in 56 cases with pure or predominant mitral stenosis (42 open commissurotomy, 14 valve replacement). Grade I or grade II echo-pattern was a good indicator for mitral commissurotomy. Grade IV pattern was a reliable criterion for valve replacement. Mitral valve replacement should be also considered in cases with grade III pattern, 38% of whom underwent valve replacement. C-E amplitude of the mitral valve was not a useful parameter in assessing the surgical procedure. Thus, the echo-pattern obtained by M-mode scan technique appeared to be of valve in planning the surgical approach for patients with pure or predominant mitral stenosis.

Adult↗
PubMed1976

Echocardiographic study on hypertrophic cardiomyopathy.

Echocardiographic study was performed on 21 cases with hypertrophic cardiomyopathy (HCM), 10 obstructive and 11 nonobstructive. Asymmetric septal hypertrophy was demonstrated in both obstructive and nonobstructive HCM. In all cases of HCM studied, the thickness of the interventricular septum was 1.4 cm or more (1.4-3.7 cm) and the ratio of septal to left ventricular posterior wall thickness was 1.4 or more (1.4-3.2). A systolic anterior movement of the mitral valve (SAM) was observed in obstructive cases only and characterized by a large backward component in late systole and an extreme approximation to the interventricular septum at its peak. Patients with HCM also showed abnormal echocardiographic indices of the left ventricular diastolic properties, such as the rate of diastolic descent of the mitral valve (DDR), mean diastolic posterior wall velocity (mPWVd), D/S ratio and mean rapid filling rate (mRFR). DDR correlated well with the ratio of rapid filling to total filling volume, rapid filling fraction, (r = 0.79, p less than 0.001), suggesting that reduced DDR in HCM was related with an abnormal left atrio-ventricular flow pattern. A significant correlation was also observed between mRFR and negative maximum dp/dt derived from the first derivative curve of the left ventricular pressure (r = o.68, p less than 0.005). Thus echocardiography was proved to be a valuable means for investigation of the left ventricular properties during early diastole.

Adolescent↗
PubMed1975

Echocardiographic classification of hypertensive heart disease. A correlative study with clinical features.

Forty patients with systemic hypertension were classified into 4 types based on the left ventricular echocardiographic findings. Patients with normal left ventricular echogram, type I, showed little clinical symptoms and signs of hypertensive involvement. Higher systolic pressure and marked hypertensive retinal and renal changes were observed in patients with symmetric hypertrophy of the left ventricle, type II. Congestive heart failure was dominantly present in those with dilatation of the left ventricle, type IV. High voltages and marked ST-T changes in electrocardiogram were usually found in patients with asymmetric septal hypertrophy, type III, while retinal and renal damages were mild. Left ventriculograms obtained from 6 cases in type III also revealed hypertrophy of the interventricular septum and one of them demonstrated left ventricular outflow tract obstruction. These cardiac features in type III, which are quite similar to those in hypertrophic cardiomyopathy, seemed to be a secondary change induced by systemic hypertension on the basis of some predisposition.

Adolescent↗