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Biomedical subjects

H Thomson

Publications and source records attributed to H Thomson.

At least 37 records · Page 2Linked to original sources

Cutaneous hemangiomas and lymphangiomas.

This article describes but the tip of the congenital vasoformative iceberg. Much has been left unsaid. The problem is very common, and it is hoped that with continued clinical prudence we can advance and improve our treatment modalities, particularly in those areas in which we fall so short!

Female

The corticotrophic cells of the canine pituitary gland in pituitary-dependent hyperadrenocorticism.

The distribution of specifically stained corticotrophic cells has been studied in the pituitary glands of 11 dogs with pituitary-dependent hyperadrenocorticism. The results suggest that the disease is not a single entity, and that some cases are caused by primary abnormality of the pituitary gland whereas others appear to be the result of dysfunction of the hypothalamus or central nervous system. The patterns correspond closely to those demonstrated in the human pituitary gland in Cushing's disease, and confirm that the canine disease is a useful model for the study of the pathogenesis of the variants of the condition.

Adrenocorticotropic Hormone

The role of prophylactic antibiotics in appendectomy using delayed primary closure.

A prospective randomized trial of prophylactic antibiotics in 202 patients undergoing appendectomy is reported upon. The antibiotics used were metronidazole and cephradine. Half of the patients received antibiotics preoperatively. The other half received antibiotics at operation only upon finding perforation, gangrene or pus formation. All wounds were treated by delayed primary closure. No instance of wound infection, defined as abscess formation or cellulitis, occurred in either group. Antibiotics given prophylactically in every instance appear to have no advantage in preventing wound infection when delayed primary closure is used.

Adolescent

Single-layer anastomosis in the large bowel: ten years' experience.

Satisfactory experience with single-layer colorectal anastomosis during 1969-74 led to an analysis of the results of single-layer large bowel anastomosis during the subsequent years 1975-79. This technique has continued to be associated with a low incidence of anastomotic failure, but anastomotic integrity also depends on rigorous attitudes to bowel preparation, to bacterial contamination and to the avoidance of anastomosis when the risk of anastomotic failure is high.

Aged

Is a fat stitch necessary?

Two hundred and eight consecutive patients undergoing surgery were allocated randomly in a trial of the use of a plain catgut subcutaneous fat stitch, compared with no fat suture. There was no appreciable difference between the two trial groups in wound infection rate following either clean (4 out of 74 with and 1 out of 68 without a fat stitch) or contaminated operations (4 out of 27 with and 4 out of 41 without). Likewise, there were no differences in haematoma rates. There is therefore no appreciable benefit to be derived from the use of this stitch.

Adipose Tissue

Solitary rectal ulcer: always a self-induced condition?

Solitary rectal ulcer is a curious and uncommon condition of contentious aetiology. Six patients seen at Gloucestershire Royal Hospital during 5 years have been studied. In 4 self-interference was certain and likely in one other; no information was available concerning the sixth. Our evidence suggests that the disease is self-induced.

Adolescent