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Biomedical subjects

H Thiele

Publications and source records attributed to H Thiele.

At least 109 records · Page 6Linked to original sources

[Extra-anatomical bypass in aorto-iliac obstruction].

Our report describes the results of 35 extra-anatomic bypass operations for the treatment of aortoiliac occlusion in high-risk patients. This operation is an alternative to amputation for the therapy of claudication intermittens or gangrene. Long-term results are difficult to obtain, as many patients in this group die early from other causes. The problem of iatrogenic steal phenomenon is discussed. We consider Doppler ultrasound assessment a very valuable method for excluding aortoiliac insufficiency of the donor limb, not detected by other means.

Aged↗

Side-chain mobility and the calculation of tyrosyl circular dichroism of proteins. Implications of a test with insulin and des-B1-phenylalanine insulin.

Previous calculations using crystal structure coordinates (Strickland and Mercola [1976], Biochemistry. 15: 3857) have predicted that about 40 percent of the calculated tyrosyl circular dichroism of hexameric insulin is due to one of the four tyrosine residues: viz. the A14-tyrosine interacting with the nearby B1-phenylalanine ring group. We have tested this prediction by measuring the tyrosyl circular dichroism of an isomorphous analogue of insulin, des-B1-phenylalanine-insulin. Contrary to expectation, the resulting circular dichroism was the same as that of insulin. It is concluded that the B1-phenylalanine residue does not in fact make a large contribution to the circular dichroism of A14-tyrosine. This result is probably due to the thermal motion of the B1 and A14 ring groups not taken into account by the calculations. An example of the effects of thermal motion on the calculated circular dichroism is given and improvements that do take into account thermal motion are discussed.

Circular Dichroism↗

[Roentgenologic diagnosis of agenesis of the gallbladder (author's transl)].

A 58-year-old female with a surgically confirmed agenesis of the gallbladder is resported. Infusion-cholegraphy revealed a bud-like bulging of the common hepatic duct with a diameter of 6 mm. Celiac arteriography did not demonstrate cystic arteries supplying the gallbladder. As combined malformations celiac arteriography revealed an accessory spleen and a small hamartoma of the liver.

Abnormalities, Multiple↗

[Vaginal rupture with prolapse of the small intestine].

We report on a case of recidival rupture of an enterocele with vaginal rupture and incarceration of small bowel. This event was probably caused by an extreme insufficiency of the patient's connective tissue. In literature four similar cases have been reported.

Female↗