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Biomedical subjects

H Tellkamp

Publications and source records attributed to H Tellkamp.

At least 37 records · Page 2Linked to original sources

[Radiation dosage of the lens and gonads in selected CT studies].

The article is a compilation of data on the radiation exposure during the most important CT examinations. The influencing parameters are assessed and their effects are discussed. Conclusions are drawn to modify the practical approach. These results are compared with those reported in international literature.

Brain↗

[Dynamic CT in the follow-up assessment of irradiated intracranial tumors].

The importance of follow-up monitoring of the course of irradiated intracranial tumours was underlined by a study of 98 cerebral dynamic computer tomograms made on 38 irradiated intracranial tumour patients. It is demonstrated that dynamic cerebral CT is a sensitive method for assessing tumour vascularisation and for assessing a disturbance of the blood-brain barrier. An adequately adjusted and standardised examination programme is demonstrated and recommended for determining the blood-brain barrier disturbance. The assessment criteria of the density-time curves for evaluating the radiotherapeutic effectively are presented; in this connection, the change in tumour vascularisation. In conclusion, the article explains the most important indications for cerebral dynamic CT in intracranial tumours.

Astrocytoma↗

[Computerized tomography studies in the assessment of radiogenic pneumopathy in an animal experiment].

An animal experimental study was conducted in 56 piglets exposed to radiation to establish new assessment criteria on radiogenic pneumopathy by employing computed tomography for diagnosis. The accurately measurable density changes in the lung parenchyma exposed to radiation appear invariably as soon as a dose-dependent threshold value is exceeded. Tolerance limits can be determined for 60Co and neutron irradiation in different fractions and single doses, the enhancement of lung density being correlated with the irradiation dose. It is not possible to establish a volume-dependent decrease in the tolerance dose. Likewise, there is no radiation-promoted co-reaction of adjacent pulmonary tissue not subjected to irradiation exposure. These results apply to the experimental animals used in the study.

Animals↗

[Clinical and computed tomographic observations on newborn infants with generalized brain edema due to perinatal asphyxia].

We observed a sudden respiratory arrest in four term newborn infants after a clinically symptom-free period. There were no cardiac, pulmonary or metabolic changes responsible for these events. Signs of cerebral dysfunction existed (muscular hypotonia, jitterness, seizures). Cranial computerized tomographic scans were performed during the period of respirator treatment within the first week of life. The density of the brain structures was significantly decreased in all cases, three of the patients showed a complete compression of the lateral ventricles. These findings indicated severe brain swelling as a consequence of cerebral hypoxia. There was a history of umbilical cord occlusion in two cases. In the remaining patients we must assume an undetected hypoxic-ischemic episode prior to the onset of labor. We used hyperventilation, corticosteroids, phenobarbital, diuretics and fluid restriction for therapy. Later on the babies received special physiotherapy. Control CT-scans were performed during the fourth or fifth week of life. The findings were normal in one patient. Signs of mild focal brain atrophy developed in two babies. A more severe cortical atrophic lesion of both temporal lobes was found in one patient. He suffered from a slight cerebral palsy. No neurodevelopmental handicaps could be found in all the other patients on long term follow-up. The EEG examination was performed between the fifth and seventh month of life. No pathologic changes were observed. We conclude that severe generalized brain edema in the newborn is not necessarily followed by extensive brain damage. We think it important to develop more sensitive methods for detecting a hypoxic ischemic crisis preceding the birth.

Asphyxia Neonatorum↗

[Radiation exposure of the lens during CT of the orbital area].

The exposure of the lens to irradiation in CT examination of the orbita was determined in a total of 80 patients via thermoluminescence dosimetry. Depending on a wide variety of parameters, exposures between 6.5 and 75 mGy were found with a mean of 28 mGy. By analysing the influence values thickness of layer and mAs product, suggestions for optimising orbita CT examinations are evolved.

Humans↗

[Radiologic studies of the correlation between the mineral content of the peripheral and axial skeleton].

Estimations of mineral content of normal human skeletons using three radiological methods have led to the following conclusions: 1. Bone density of vertebral bodies increases from T.6 to L.5. Average values for thoracic and lumbar vertebrae are 0.71 and 0.88 g./cm2. 2. There is no linear correlation between the mineral content of an easily accessible peripheral bone and of the vertebrae. 3. The method for bone mineral estimation, using thulium170, which was developed in Dresden, can be used for the peripheral and central skeleton. 4. 125-photon absorption us useful for measurements on the peripheral skeleton, where it is the most elegant and accurate method. It is, however, useless for measurements of the central skeleton.

Adolescent↗