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Biomedical subjects

H Takiff

Publications and source records attributed to H Takiff.

43 records · Page 3Linked to original sources
PubMed1984

Gallbladder disease in childhood.

Seventy-seven children less than 19 years old underwent cholecystectomy during a 12-year period at UCLA Medical Center. Forty-four had calculous cholecystitis; five had acalculous cholecystitis; and 28 underwent cholecystectomy with other major biliary surgery. In more than half of the patients with calculous cholecystitis, a cause for cholelithiasis could be identified, most commonly total parental nutrition use. Those without an identifiable etiology were all females, were older, were generally obese, had a family history of gallbladder disease and had a higher likelihood of adult-life symptomatology. Cholelithiasis was best demonstrated by ultrasound and oral cholecystogram. Children with biliary atresia, choledochal cysts and other anomalies of the extrahepatic biliary system will benefit from cholecystectomy associated with reconstruction of the ductal system. Mortality and low morbidity were not related to cholecystectomy.

Adolescent↗
PubMed1984

Management of mucocutaneous herpes simplex virus infections.

Herpes simplex virus type 1 and 2 are causes of common inflammatory conditions of the mucous membranes and skin. The proper management of these infections begins with an accurate diagnosis. Viral cultures should be performed whenever possible. Patients should be counselled regarding the proper care of lesions, the risk of complications, the likelihood of experiencing recurrent infection, and should be urged to avoid intimate contact while lesions are active. Antiviral therapy is now available to ameliorate the symptoms and shorten the duration of infection in selected patients, but does not prevent recurrences. Topical, oral and intravenous preparations of acyclovir are effective in treatment of primary herpes simplex infections. Immunosuppressed patients with herpes simplex infections also benefit from acyclovir therapy. Oral activity has some activity in ameliorating recurrent genital herpes and should be considered for patients who are particularly troubled by their infections.

Acyclovir↗
PubMed1984

Oral acyclovir to suppress recurring herpes simplex virus infections in immunodeficient patients.

Thirty-two episodes of herpes simplex virus infection in four immunodeficient patients with frequent recurrences were successfully treated with oral acyclovir, one capsule five times a day for 5 days. In 23 of these episodes, the treatments were extended for 1 to 6 months using two to five capsules a day with the aim of suppressing expected recurrences. In these patients, who routinely had more than one recurrence per month before treatment, there were only six outbreaks during more than 60 patient-months of suppressive therapy. Infection always recurred after treatments were completed, but the time to recurrence was shorter after treatments with two acyclovir capsules per day than after treatments with five capsules per day (p less than 0.001).

Acyclovir↗
PubMed1984

Effect of arteriovenous fistula on wound healing and skin blood flow.

In dogs, the tension in a surgical incision and a measure of subcutaneous blood flow were obtained adjacent and distal to a groin arteriovenous (A-V) fistula. At 7 days, in the fistula-bearing leg compared with the control there was an increased force required to separate the wound edges adjacent to the fistula, while the opposite was true for the distal incision. Radioxenon washout, used for a measure of subcutaneous blood flow, was more rapid distally in the control leg. In the fistula leg this relationship was reversed. These studies indicate there is a redistribution of blood in the leg when an A-V fistula is constructed, with augmented subcutaneous flow and increased wound strength adjacent to the fistula and the converse at a distal site in the limb.

Animals↗
PubMed1983

Risk of renal failure after major angiography.

In 400 patients who underwent major aortography, acute renal dysfunction (ARD) occurred in 11.3%. Of the group with normal renal function before the procedure, 8.2% had ARD and 0.8% required dialysis. Patients with prior abnormal renal function had a 41.7% incidence of ARD, and 8.3% required dialysis as a result of angiography. Vigorous intravenous hydration was used in all patients but did not completely prevent renal problems. Two risk factors not previously emphasized were the injection site (higher risk with abdominal aortic studies) and presence of congestive heart failure requiring treatment with digoxin. Other notable risk factors included contrast load and age. These results emphasized that even with modern contrast agents and application of current concepts of treatment, there remains a risk of renal injury with major angiography.

Acute Kidney Injury↗