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Biomedical subjects

H Szarmach

Publications and source records attributed to H Szarmach.

At least 19 recordsLinked to original sources

[The effect of occupational environment on the development of skin lesions in workers at a tableware porcelain plant].

This work reports on the skin diseases which occur among the workers of the ceramic industry. The most frequently observed diseases were: dermatomycosis, eczema as a result of wear, and allergic diseases. Nickel, and also cobalt, turpentine, paraphenyldiamine and detergents were the main allergens. Mycotic infection was observed primarily among the workers using common bathrooms.

Adult

[Labial flaps in reconstruction of lower lip].

The authors present the evolution of the lower lip reconstruction by labial flaps. Some details of the operation technique and the range of indications for this type of plastic operation have been discussed.

Humans

Epidemiology of nickel allergy: results of a follow-up analysis of patients with positive patch tests to nickel.

In a previous paper, we reported on nickel sensitivity in 2400 consecutive patients in 5 countries. 3 years later, we reassessed 104 of the 157 nickel-positive patients of this former study and found 13 now to be negative to nickel sulphate. Nearly all the others can no longer tolerate nickel contact. 68 patients were free from nickel dermatitis, 16 showed a very mild eczema or dyshidrosis, and 13 were suffering from chronic hand dermatitis. 42 of 104 patients had changed their occupation, 36 successfully, with clearance of skin lesions. Rehabilitation by avoidance of nickel-containing costume jewelry, wrist-watches and clothing buckles, and by change of occupation, is possible and necessary.

Dermatitis, Contact

[Mixed infections of the urogenital tract with Trichomonas vaginalis and yeast-like fungi in humans with reference to treatment].

Comparative studies on the incidence of mixed infections with T. vaginalis and yeast-like fungi in man carried out within the years 1969-1980 and 1981-1984 showed a progressive increase of this kind of disease. Clinical treatment with Clotrimazole was performed in 35 patients. Local therapy with Clotrimazole was effective, if 3-5 days later the patients receive Tinidazole at one dosage. In some patients, the therapy has to be continued with Metronidazole.

Administration, Oral

Ciprofloxacin in acute male gonorrhea.

100 male adults suffering from acute gonococcal urethritis were hospitalised and treated with decreasing doses from 2000 mg to 100 mg of ciprofloxacin (1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid, Bay o 9867; designated tradename: Ciprobay). Clinical signs (burning, exudate, edema, inflammation) and bacteriology (native and culture) were assessed hourly during the first 9 h and at 12, 24 and 72 h after start of therapy. Most patients were controlled during 10 days. 99 patients showed clinical and bacteriological cure. One patient with subacute gonococcal urethritis (protocol violation) did not react on 250 mg. No postgonococcal urethritis was seen. No side effects were reported. For the acute male gonococcal urethritis a 100 mg single dose treatment with ciprofloxacin can be recommended.

Acute Disease

[Trichomoniasis of the urogenital tract in patients hospitalized in 1976-1983].

We report on investigations carried out on T. vaginalis and mixed infection (T. vaginalis and yeast-like fungi). Special attention was paid to metronidazol resistance on T. vaginalis strains isolated from patients who had been repeatedly treated with this medicament. Therefore we point to the necessity of defining the patients' susceptibility to this remedy.

Adolescent

[Limitations of indications of clotrimazole-hydrocortisone and its components. A double-blind study].

Efficacy and tolerability of ointment/water emulsion, containing the combination of clotrimazole and hydrocortisone (Canesten HC) were compared with the two components. 4 groups of indications were chosen and 192 (16 X 3 X 4) patients treated. In all groups and symptoms of this comparison the best efficacy was with the combination product. Side effects which have to be attributed to this topical treatment could not be detected.

Clinical Trials as Topic

[Diagnostic and epidemiologic significance of multinuclear and round forms of Trichomonas vaginalis].

Trichomonas are analyzed in the material taken directly from the urogenital tract of male and female patients cultivated on Roiron medium and using different methods for staining the preparations was carried out. It is observed that some of the preparations examined show round nuclear forms of T. vaginalis impossible the detect by laboratory methods used up to now. The techniques used in this study decrease the risk of false diagnosis of these forms of trichomoniasis by less experienced examiners thus facilitating correct diagnosis and therapy. It should be also said, that they are simple and easy to carry out in the laboratory.

Diagnosis, Differential

[Effect of different cytostatic agents and antibiotics on the biology of Trichomonas in vitro].

The purpose of these examinations was an attempt to elucidate the influence of some cytostatic preparations (Fluorouracil, Triaziquone (Treminon), Mechlorethaminee Oxide Hydrochloride (Mitomen), Methotroxate, Mitomycins, Cyclophosphamide (Endoxan), Mechlorethamin (Nitrogranulogen) and antibiotics (Penicillin, Streptomycin, Aureomycin, Nystatin) on formation of the multinuclear forms of Trichomonas under the conditions of culture on artificial medium and to investigate the cidal and static effects of chosen cytostatics and antibiotics of different species of Trichomonas in vitro. It was found that Mechlorethamine (Nitrogranulogen) and Mitomycins have distinct influence on formation of the multinuclear forms of Trichomonas in culture. Similar effects were observed in the antibiotic group with aureomycin only if applied pure or combined with other antibiotic drugs. In addition, it was shown that Triaziquone (Treminon) exerts the strongest effects on the examined species of Trichomonas.

Anti-Bacterial Agents

Clinical studies on the effectiveness of Wratizolin in the treatment of some dermatoses.

Clinical studies on therapeutic effectiveness of ITCL applied as 2-3% ointment, 2% cream and 2-3% lotion were carried out. The study material included 96 patients at the age of 9-80. Of this group, 19 patients were with herpes zoster, 16 with herpes simplex, 29 with eczema complicated by secondary bacterial infection, 30 with palm and foot pustulosis, 1 patient with actinic cheilitis and 1 with varicella. The results obtained have revealed that the preparation is particularly effective in the treatment of dermatoses induced by herpes zoster and herpes simplex virus.

Administration, Topical

[Clotrimazol therapy of skin mycoses].

Clinical evaluation of a 1% clotrimazole cream and solution on 236 in and out patients with different clinical manifestations of mycotic infections was done. Clotrimazole, both cream and solution, is an effective and well tolerated agent in the treatment of infections due to dermatophytes and yeasts. Best results were recorded with patients suffering from pityriasis versicolor and erythrasma, and interdigital erosion.

Administration, Topical