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Biomedical subjects

H Suprun

Publications and source records attributed to H Suprun.

29 records · Page 2Linked to original sources

Metastatic carcinoma in histologic sections of aspirated bone marrow: a comparative autopsy study.

The incidence of metastatic carcinoma in bone marrow was studied by two different approaches in 220 consecutive autopsies of patients with carcinoma: histologic sections of aspirates from the iliac spine, as usually done in living patients; and gross and microscopic examination of the thoracolumbar spine. Ten percent of the autopsies showed bone marrow metastases by the aspiration technic as contrasted with 34.5% by the autopsy technic. Three cases had positive bone marrow aspirates in the absence of metastases demonstrable by routine autopsy. The combination of autopsy and aspiration technics yielded an incidence of metastatic marrow involvement of 35.9%. Of patients with marrow metastases at autopsy, 25% also had positive aspirates. This study establishes a norm for the comparison of the efficiency of discovery of metastatic carcinoma by different modalities of clinical bone marrow sampling.

Autopsy

A correlative cytohistologic study on the interrelationship between exfoliated urinary bladder carcinoma cell types and the staging and grading of these tumors.

The purpose of this sutdy was to demonstrate the existence of a certain correlation between the type of exfoliated malignant tumor cells (transitional and/or epidermoid) in 28 bladder tumor cases, and the stage of these tumors as evidenced in histologic sections of full-depth bladder biopsies or cystectomies. This investigation permitted not only correlation of the type of malignant cells with the stage but also with the grade of these tumors. However, this study should be followed by more investigations based on quantitative analyses or cytomorphometric approaches in order to reach more definitive results.

Adult