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Biomedical subjects

H Stopfkuchen

Publications and source records attributed to H Stopfkuchen.

At least 55 records · Page 3Linked to original sources
PubMed1984

[Diagnostic value of CK-MB isoenzyme determinations in children with craniocerebral injuries and polytrauma].

Total creatine kinase (CK) and its myocardial isoenzyme (CK-MB) were determined in 71 children with isolated acute head injury (N = 30), with head injury and polytrauma but without chesttrauma (N = 11) and with head injury and polytrauma including chest trauma (N = 30) on the second and third day after injury. Electrocardiograms were recorded in 56/71 children on each of the first three days in hospital. Elevations of CK-MB isoenzyme over 6% respectively over 10% of total CK are found as frequently in children with head injury without chest trauma as in children with head trauma and chest trauma. In addition there is no significant correlation between the level of the CK-MB and the incidence of ECG features characteristically associated with heart contusion. This study shows that the determination of CK-MB cannot be used as a criterion for diagnosing heart contusion in children with head injury. The finding of CK-MB in the serum of 53% children with isolated head injury exceeding 6% of total CK, and in the serum of 33% children exceeding 10% of total CK strongly suggests myocardial damage to be a frequent complication of cerebral damage with consecutive extreme sympathetic stimulation.

Adolescent↗
PubMed1984

[Dobutamine in childhood].

The synthetic catecholamine Dobutamine has potent inotropic effects. It is frequently used in the management of adult patients with low cardiac output and elevated left ventricular enddiastolic pressure not yet associated with systemic hypotension. The few available informations on hemodynamic effects of Dobutamine in children emphasize the effectiveness of this sympathomimetic amine also in the treatment of children especially older than 12 months with acute low cardiac output states. Neonates and infants appear to respond to Dobutamine as well, but possible changes in cardiovascular structure and function accompanying growth which are discussed and which could cause a considerable variance in individual patient response, require an exceptionally close monitoring of the hemodynamic effects of Dobutamine in this age-group.

Adolescent↗
PubMed1984

[Standardized morphometric studies of the right pulmonary artery in the suprasternal M-mode echocardiogram in childhood].

236 children of all age-groups, without any evidence of cardiopulmonary disease, underwent measurement of the diameters of the right pulmonary artery (RPA) in the suprasternal M-mode echocardiogram with respect to the characteristic motion pattern of the RPA. Since a high correlation was found between these diameters and height (r = 0.94; y = 1.66 square root X - 6.19), the children were divided into 9 sub-groups according to height, and mean values were calculated for all parameters in each sub-group. The systolic expansion of the RPA ranged from 18% to 30% within groups and correlated only weakly to height (r = 0.28). Suprasternal echocardiographic standards for measurement of the RPA may enhance the usefulness of this echocardiographic approach in pediatrics.

Adolescent↗
PubMed1983

[Care of severely asphyctic preterm and term infants].

We present a complex monitoring procedure for preterm and term infants with severe perinatal asphyxia and/or shock. It includes arterial and central venous catheters and occasionally a pulmonary artery catheter. The monitoring system provides rapid information on a number of parameters which can be used to improve the quality of ventilation and drug treatment. Therapy induced side effects are more rapidly detected and corrected. Handling of the baby is reduced and thereby the otherwise resulting increase in blood pressure and ensuing danger of cerebral hemorrhage.

Asphyxia Neonatorum↗
PubMed1983

[Hemodynamic reactions to intraventricular hemorrhage].

In a 13-year girl with head injury the hemodynamic parameters during 2 episodes of intraventricular hemorrhage were monitored. There were hyperdynamic values for heart rate, Cardiac output, mean arterial and pulmonary artery pressures, systemic vascular and pulmonary vascular resistances. It is likely that centrogenic, sympathico-adrenergic reactions are the cause of pulmonary failure after isolated head injuries.

Adolescent↗
PubMed1981

[Hemorrhagic pulmonary edema and cardiac failure following isolated head injury. Treatment with dobutamine and nitroglycerin (author's transl)].

A 12 year boy with an isolated head injury and subdural hematoma developed neurogenic pulmonary edema and intraoperatively a low cardiac output syndrome. The postoperatively depressed cardiac function and hemorrhagic pulmonary edema were treated with Dobutamine and Nitroglycerin given intravenously. The beta-1-stimulating catecholamine was used because of its positive inotropic effect, to reduce pulmonary capillary pressure and to improve the afterload. Nitroglycerin applied in a low dosage with exclusive venodilator effect was added for treatment of pulmonary edema and left ventricular failure. About 2 1/2 h after the start of the treatment pulmonary edema had subsided and circulation was stabilized.

Brain Injuries↗
PubMed1980

[Rheumatic fever: present status (author's transl)].

In general, there is a falling incidence of rheumatic fever in the Federal Republic of Germany. Data from 1949 to 1977 at the University Children's Clinic Mainz indicate that in the last few years rheumatic carditis and arthritis occurred with the same severity and frequency in relation to the total number of cases as 20--25 years ago. Merely the number of recurrences has been significantly lowered since the introduction of penicillin prophylaxis. The reduction in recurrences is the main reason why acquired heart disease has become less common.

Adolescent↗
PubMed1979

[Complications and survival rate in preterm infants and neonates treated with mechanical ventilation (author's transl)].

Between January 1972 and December 1976 201 preterm infants and neonates were treated with mechanical ventilation. These children were classified into 6 groups according to the indications for mechanical ventilation: P = respiratory failure caused by pulmonary disease; Z-P = respiratory failure caused by cerebral disturbance with simultaneous respiratory disease; Z = respiratory failure caused by cerebral disturbance; C = respiratory failure caused by cardiac disease; SCH = respiratory failure through shock; M = respiratory failure caused by mechanical disturbance; Bronchopulmonary complications developed in 70% of the survivors and in 60% of the fatalities. The most serious bronchopulmonary complications were infections which occured with similar frequency in all indication groups as late-onset complications, and air-leaks which occured as early complications. The latter complication was significantly higher (38%) in the first than in the other groups. The most serious extrapulmonary complications were seizures, intracerebral hemorrhages and septicemia. 71 of the 201 patients survived. There was a significant increase in the survival rate from 21.2% in 1972-1973 to 43% in 1974-1976. The survival rates differed significantly within the indication groups. The best result was found in the p-group followed by the Z-group. The highest mortality rate was found in the SCH and C-group.

Bronchial Diseases↗
PubMed1978

Massive digoxin intoxication in childhood.

In a 10 year old boy 8 hours after taking about 16 mg beta-acetyl-digoxin a maximum serum digoxin level of 31.8 ng/ml was measured radioimmunologically. This is the highest digitalis level in childhood described to date. The serum potassium level rose to 7.4 mmol/l. Complete atrio-ventricular block, and salves of ventricular premature beats were the most serious rhythm disturbances. The absence of life threatening rhythm disturbances is attributed to the early use of diphenylhydantoin in small frequent doses.

Child↗
PubMed1978

[Acute anuria due to renal candidiasis in infants (author's transl)].

There are reports here on three cases of renal candidiasis in infancy which after predisposing factors suddenly led to a deterioration in the general state, to a considerable enlargement of the kidneys and to the occurrence of an anuria. The pecularities of the course as well as a conservative treatment success using 5 fluorcytosin are reported on. The pathogenesis of the illness is discussed.

Acute Disease↗