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Biomedical subjects

H Steiner

Publications and source records attributed to H Steiner.

At least 217 records · Page 12Linked to original sources
PubMed1990

[Color-coded duplex sonography and the resistive index in dysfunctional kidney transplants].

In a prospective analysis we performed 182 colour duplex US studies in 60 patients with renal transplants to determine the effects of different causes of graft dysfunction on the resistive index (RI) and the colour imaging pattern of the transplant arteries. Allografts with normal function, cyclosporin toxicity, cytomegaly infection, acute tubular necrosis, glomerulonephritis and postoperative functional nephrotoxicity showed normal RI (less than 0.7) and normal pattern of the arteries in colour duplex. Grafts with acute and chronic rejection, obstructive uropathy and arteriolosclerosis showed significant elevated RI and in colour duplex always a characteristic blinking of the arteries and a numerical reduction of the peripheral arteries. It seems that the assessment of an increase of vascular impedance is possible also with colour duplex US.

Adult↗
PubMed1990

[Traumatic embolization of the middle cerebral artery].

A 3 mm metallic particle, which had blasted during grinding operation, shot into the neck of a nine year old boy, penetrated into the common carotid artery and embolized the right middle cerebral artery. There had been no neurological symptoms until four days after the injury. Suddenly, a mild left side hemiparesis occurred with accentuation of the arm. The case illustrates an unusual penetration and intravascular migration of a foreign body. After the injury, penetration and subsequent peripheric embolisation can happen immediately, or as in our case within a short time after. Hence, the small particle may not be detected by a local radiogram, or may not be found on surgical exploration. Therefore, in all cases of neck wounds caused by low velocity injection of foreign bodies, radiological evaluation with skull-x-rays and a neurological examination should be done. If further special scans are required, these should be accomplished by axial computer tomography, because the metallic nature of the foreign bodies would prohibit the examination by magnetic resonance.

Carotid Artery Injuries↗
PubMed1990

Depression, episodic behavioral dyscontrol, and polydipsia following right temporal lobe damage.

A patient referred to the authors for evaluation and treatment of depression, behavioral dyscontrol syndrome, and polydipsia is described. The authors reviewed his medical status and, finding damage to his right temporal lobe, conceptualized his symptom constellation as representing interictal syndrome and treated him with carbamazepine. His affective symptoms, but not the polydipsia, improved following treatment with carbamazepine.

Adult↗
PubMed1990

Compliance and outcome in anorexia nervosa.

Anorexia nervosa is notoriously difficult to treat, but little is known regarding the relationship of compliance to treatment outcome. We investigated in 41 adolescents who fulfilled DSM-III-R criteria for anorexia nervosa, the relationship between the completion of a standard psychosocial treatment program, subtypes of anorexia nervosa, and outcome as determined by standardized measurements. These adolescents were observed for an average of 32.4 months. Overall, 29 patients (70%) improved considerably, but 10 (24%) were symptomatic, and 2 (5%) remained in poor condition. There were no deaths. Of the 41 patients, 14 (34%) completed our entire treatment program, 15 (37%) received major treatment and failed in the outpatient follow-up phase only, 7 (17%) dropped out of inpatient treatment before its completion, and 5 (12%) refused treatment in our system altogether. Of all the dropouts, 10 received no further treatment. One patient was admitted to hospital elsewhere but again dropped out in the outpatient phase of that program. Seven patients (17%) received further outpatient treatment only, and 9 (22%) received inpatient and outpatient care and seemingly completed their treatment. Treatment completion significantly affected the measures of global clinical functioning and specific psychopathologic features, but only for those patients who completed the initial program. Bulimic patients did considerably worse on follow-up and were less likely to complete treatment. Patients with restricted anorexia nervosa were more likely to complete treatment than those with a bulimic subtype (P = .03). Differential compliance rates in the two subtypes confound the effects of treatment completion and need to be controlled for in future studies. Depression was not associated with noncompliance but, if present, was associated with poor outcome on follow-up and abated in only a third of those in whom it was initially present.

Adolescent↗
PubMed1989

Asymmetries in crossed and uncrossed nigrostriatal projections dependent on duration of unilateral removal of vibrissae in rats.

The influence of unilateral removal of vibrissae on the crossed and uncrossed nigrostriatal projections was examined with the horseradish peroxidase tract tracing technique. Hemivibrissotomy mainly affected the projections arising from the rostral part of the substantia nigra. One to three days after clipping the vibrissae, rats were found to have more labeled neurons in the crossed projection to the caudate-putamen (CPU) on the same side as vibrissae removal than in the crossed projection to the CPU opposite to vibrissae removal. A reversed asymmetry was seen in rats examined 4-20 days after vibrissae removal. These animals had more labeled cells in the crossed and uncrossed projections terminating in the CPU opposite to the shaved side, i.e. in the hemisphere deprived of vibrissal sensory input. This time-course of neural alterations is similar to that of the recovery from behavioral asymmetries seen after hemivibrissotomy. Similar time-dependent alterations in the nigrostriatal projection had been found after unilateral injection of 6-OHDA into the substantia nigra.

Animals↗
PubMed1989

Histidyl proline diketopiperazine (Cyclo [His-Pro]) in eating disorders.

The authors explored the role of Cyclo [His-Pro] (CHP) in 50 adolescents who fulfilled DSM III diagnostic criteria for anorexia nervosa and bulimia. CHP, a relatively new neuro modulator which has a role in inducing satiety, was assayed in serum during routine blood work. CHP levels correlated significantly with weight in restrictor (AN-R) (R = -0.449, P less than 0.05) and bulimic anorexics (AN-B) (R = +0.489, P less than 0.01). There was no significant correlation in normal-weight bulimics (NWB) (R = +0.556, P less than 0.01). It did not correlate with weight in a depressed control group. Longitudinal data on six patients showed a similar relationship between weight, purging and CHP binge/purge activity and/or weight changes of around 2 kilograms correlated with average CHP changes of 42%. Clinical material suggests changes in satiety during CHP changes consistent with a satiety disturbance model of these disorders.

Adolescent↗
PubMed1989

Analysis of recovery from behavioral asymmetries induced by unilateral removal of vibrissae in the rat.

Unilateral removal of vibrissae in rats induces an asymmetry in the side of the face used to scan the wall while traversing the edge of an open field (thigmotactic scanning). This behavioral asymmetry recovers over time. The time course of asymmetry and recovery was systematically analyzed by testing groups of rats deprived of vibrissae for different periods of time. The preferential use of the hemiface with intact vibrissae persisted up to 3 days after vibrissae removal. It was expressed maximally during the first minute of testing. This phase was followed by a rapid return to symmetry by Day 6. Recovery to symmetry involved both a decrease in duration of scanning with the vibrissae-intact side and an increase with the vibrissae-clipped side of the face, with the total duration remaining constant throughout the states of asymmetry and recovery. The time course of behavioral recovery corresponds to the time course of neural plasticity in the basal ganglia that accompanies hemivibrissotomy, a result suggesting a functional link between the two phenomena.

Animals↗