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Biomedical subjects

H Sośnik

Publications and source records attributed to H Sośnik.

At least 19 recordsLinked to original sources
PubMed1994

Leydig cell nodular hyperplasia in human biomorphosis.

In 120 left testicles of patients who had died suddenly or in accidents and whose age ranged from 17 to 87 years (average: 53 +/- 18 years) the percent (V%) and total weight of Leydig cells were determined. Then the V% and the total mass Leydig cells were correlated with the values of morphometrically determined structural elements of the gonad and spermatogenic activity of the seminal tubules. It was found that the V% of these cells correlated positively with the V% of tubular membranes and the proportion of hyalinized tubules as well as with the number of tubular cross-sections per test field (a). There was a negative correlation with the testicular weight, the V% of the germinal epithelium and the V% of the testicular stroma. In contrast, total weight of Leydig cells correlated positively only with the testicular weight. The amount of Leydig cells was not associated with age. Based upon the present results it is believed that nodular Leydig cell hyperplasia observed in the atrophic gonad is of relative type.

Adolescent↗
PubMed1994

[Weight (mass) of the thyroid in assessment of endemic goiter].

The weight of thyroids from cadavers in the Province of Wrocław in the year 1991 was not lower and, on the contrary it was frequently higher than in the year 1957. One of the causes of this may be incorrectly conducted iodine prophylaxis. Other causes cannot be ruled out including the influence of pollution after Chernobyl reactor disaster. The data from the Province of Lublin indicate that mass of thyroids in this region is even higher than that in the Province of Wrocław considered to be the area of goitre endemic.

Adolescent↗
PubMed1993

Studies on teratospermatogenesis occurrence in man.

In 462 left testes of males, died in the age of 17-91 years (x = 51,9 +/- 16,8 years) the occurrence frequency and the degree of teratospermatogenesis activity was assessed. In the whole material, the phenomenon occurred in 84% of cases. In 47,83% of cases the grade of intensity was low (+), in 22% high ( ), in 14% moderate (++). Alcoholic intoxication occurred to have the heaviest impact on teratospermatogenesis frequency (92,5%); in liver cirrhosis the occurrence frequency was significantly more rare (76%). The age of cadavers and the weight of the gonad did not correlate with teratospermatogenesis occurrence frequency. Postmortem autolysis was not connected with the phenomenon occurrence also. It correlated positively albeit with type II and III seminiferous tubules, i.e. with tubules, where spermatogenesis was stopped on the stage of spermatids and spermatocytes, and negatively with hyalinized tubules, and also with the V% value of tubular membranes.

Adolescent↗
PubMed1990

Histometry of male gonad in liver cirrhosis.

Left testicles of 125 male patients with cirrhosis and 124 control males were subjected to histometric analysis. The ages of the patients with cirrhosis ranged from 31 to 92 a (mean = 59 a) and in controls, it was from 17 to 87 a (mean = 53 a). In the testicles in cirrhosis, the mean partial value of the V% of the spermatogenic epithelium statistically decreased significantly by a factor of 1.21, that of Leydig cells by 1.32 and interstitial tissue by 1.23, while the mean value of V% of tubular membranes increased by a factor of 1.68 and that of blood vessels by 1.48. The mean partial area of the tubular cross-sections significantly decreased in the cirrhosis group by a factor of 1.3, and by the same factor, the mean number of tubular cross-sections increased per mm2 of the whole testicular sectional plane. The total volume of the tubular system decreased in cirrhosis by a factor of 1.4, and the total weight of Leydig cells by 1.8 in relation to the control group. In complete cirrhosis only, the mean partial area of tubular cross-sections decreased by a factor of 1.15, and the total weight of Leydig cells by 1.42 in relation to incomplete cirrhosis. The type of cirrhosis and the degree of its inflammatory activity were without any significant influence (with the exception of isolated elements) on the differences in the quantitative composition of testicular tissue. However, such effect was exerted by the degree of fatty infiltration of the cirrhotic liver.

Adult↗
PubMed1989

Correlation coefficient between the topological index of sudanophilic bodies (SLey) and various types of spermatogenic tubules in male gonad in human biomorphosis.

The purpose of the study was determination of the value of the correlation coefficient between the spermatogenic activity and the value of the topological index of the sudanophilic bodies (S.b.) in the ageing male gonad. The reported study was carried out on 61 left-sided testicles of individuals who died in traffic accidents or after myocardial infarction or stroke. Their ages ranges from 22 to 95 years (mean 55.2 years). A negative correlation was found between S Ley and tubules with highly progressed spermatogenesis, and a positive correlation between S Ley and tubules with arrested spermatogenesis. Of interest was the observation that the correlation became evident only in middle age. An unequivocal interpretation on these results are difficult. Further studies are suggested.

Adult↗
PubMed1988

Studies on the size of human male gonad in biomorphosis, alcohol intoxication, and cirrhosis--a review and own findings.

The size of the testicle (absolute weight, relative weight as the index X, length, and width was measured in 142 late patients aged 17 to 87 a (mean age = 54 a) serving as controls, in 193 deceased patients aged 20 to 81 a (mean age = 47 a) with a history of alcoholism, and in 136 defunct patients aged 30 to 92 a (mean age = 59 a) with cirrhosis. A significant difference in the mean size of the testicles was demonstrated between the cirrhosis group and both the control and alcoholism groups. No statistically significant differences was observed between the control group and the alcoholism group. The degree of acute alcoholic intoxication has no significant effect on the degree of testicular atrophy. Chronic alcoholism exerted a more significant effect on the degree of testicular atrophy than acute alcoholism. Coexistent cirrhosis increased this difference even more. The type of cirrhosis and the degree of its inflammatory activity had no significant influence on the testicular size. Such effect was demonstrated, however, if diffuse fatty infiltration of the cirrhotic liver was present. In the biomorphosis, the greatest mean testicular size was observed in the 4th and 5th decade of life. From the 6th decade on, the testicular size decreased statistically significantly. The curve of the values of the mean testicular size in alcoholism was more flat than in the control group and was situated below it. No statistically significant differences among the values of the testicular size in this curve were found. The testicular size curve in cirrhosis was below both these curves, and a statistically significant difference was found between the 7th and the 9th decades. The mean weight of the testicules in controls, alcoholics, and patients with cirrhosis was 17.58, 16.49, and 13.25 g, respectively, the mean volume was 16.37, 15.34, and 12.21 ml, respectively, the value of the index X was 2.47, 2.52, and 1.97, respectively, the testicular length was 5.05, 4.08, and 3.61 cm, respectively, the width was 2.93, 2.87, and 2.70 cm, respectively.

Adult↗
PubMed1986

Quantitative investigations on the topography of twelve structural elements of the male gonad.

For elucidating the problem whether the tissue composition of the male gonad is identical or different in the equatorial zone and polar zones of the organ, 104 left testes were studied obtaining them from the cadaver of patients dying from various acute and chronic diseases not affecting the endocrine system. In the histological preparations of the polar and equatorial zones of the testis, the proportion [%] were calculated of 6 types of convoluted tubules designated with numbers from 1 to 6 in the sequence of decreasing spermatogenic activity, and by the morphometric method, the proportions [%] were determined of the tubular lumina, spermatogenic epithelium, tubular membrane, stroma, blood vessels, and LEYDIG's cells. In the whole analysed group, only tubules type 2 were more numerous in the equatorial part, while tubules type 6 prevailed in the polar parts. The lumina of the tubules occupied a greater % of the testicular structure in the polar parts as compared with the central part. Other tissue elements were present in similar amounts or the differences between their amounts in these parts were only nearly significant statistically. The study showed also that the number of type 1 tubules decreased significantly with progressing age, while the number of type 6 tubules increased. A statistically significant fall of the proportion [%] of the spermatogenic epithelium and increased proportion of tubular membranes and stroma were another age-related changes. It is worth stressing that these age-related processes progressed parallelly in the equatorial part and in the polar parts of the testis which suggest that ageing of the organ occurs simultaneously in the whole gonad.

Adult↗
PubMed1985

Studies on the participation of tunica albuginea and rete testis (TA and RT) in the quantitative structure of human testis.

In 309 testes, the % proportion of the tunica albuginea (TA) and rete testis (RT) was determined in the quantitative composition of the testis. The weight of the testis ranged widely from 3.0 to 34.5 g, mean weight 14.67 +/- 6.0 g, with a statistically non-significant difference in favour of the right testis (15.3 +/- 6.32 g). The mean weight of the testes decreased with age, being 16.77 g in young men, 14.98 g in middle-aged men, and 13.6 g in old men. The absolute weight of TA and RT ranged from 1.0 to 12.0 g, being on the average 3.57 +/- 1.42 g. Similarly as the mean weight of the testis, that of TA and RT was not significantly different between the right and left testis, and between various age groups. On the other hand, a significant rise was observed in the % proportion of the mass of TA and RT in the total mass of the testis in various age groups. In young men, this proportion was 20.36%, in middle-aged men 24.28%, and in old men 28.83%. Statistically significant differences appeared between the mean values in the youngest and oldest age groups and the oldest and middle age groups. In the whole material, the % proportion of TA and RT in the quantitative composition of the testis ranged from 13.6 to 75.0%, being 25.7 +/- 8.1% on the average. Identical results were obtained by 2 different methods in men dying between 17 and 91 a of age, and the mean age of them was 58.2 a.

Adolescent↗