Biomedical subjects

H Smith

Publications and source records attributed to H Smith.

At least 919 records · Page 51Linked to original sources

PubMedDate not supplied

The hepatoprotective effect of oxygen during halothane anesthesia.

The effects of halothane anesthesia on liver function, as reflected by postanesthetic changes in serum glutamic pyruvic transaminase (SGPT) levels, were evaluated in 2 groups of 40 patients. All patients had 2 halothane anesthetics. In 1 group, both anesthetics were administered at 1 atmosphere pressure with 30% O2 in the inspired air. In the 2nd group, both anesthetics were administered at 2 to 3 atmospheres (absolute) of pressure with 97 to 98% O2 in the inspired air. While the SGPT levels remained within the normal range in all cases, there was a significant rise in SGPT levels in patients undergoing surgery under 1 atmospheric pressure. Patients undergoing surgery at 2 to 3 atmospheres pressure (absolute) had SGPT levels which remained at low normal values. The difference in response of SGPT in the 2 groups was statistically significant. We conclude that increased O2 tensions alter the normal response of SGPT to halothane anesthesia and that increased O2 tensions appear to protect the liver from possible adverse responses to halothane or its metabolites.

Adult↗

PubMedDate not supplied

Cognitive changes during the menstrual cycle.

A predominantly non-student group of sixty-five women volunteers, screened for medication use, prospectively completed the Moos Menstrual Distress Questionnaire (MDQ) and the Temporal Disorganization Scale (TDS) weekly for one month along with a daily calendar of menstrual status. Data analysis revealed that TDS, concentration disturbances, negative affect, pain and water retention were rated as higher premenstrually and menstrually. Women dichotomized into groups based on high and low premenstrual TDS scores demonstrated different symptom patterns across the menstrual cycle. For the high premenstrual TDS group, concentration, behavioral change, negative affect and pain were all rated highest premenstrually; for the low premenstrual TDS and group the TDS score was rated highest menstrually. The relevance of these findings to literature reports of associations between psychopathology and menstrual cycle phase are discussed.

Adult↗

PubMedDate not supplied

Anger and locus of control in young women with and without premenstrual syndrome.

The purpose of this study was to examine differences in locus of control and anger in college women with and without premenstrual syndrome (PMS). One hundred thirty-seven female undergraduates completed a biographical questionnaire, the Rotter Internal-External Locus of Control (I-E) Scale, the Spielberger State Trait Anger Scale (STAS), the Framingham Anger Scale (FAS), and a women's health questionnaire. After 65 women who had had children or used hormonally based contraceptives or psychotropic medications were excluded, the remaining subjects were placed into a PMS (n = 48) or a non-PMS group (n = 24) according to whether they met DSM-IV criteria for Premenstrual Dysphoric Disorder (PMDD). After debriefing the sample, the women were asked if they believed they had PMS. Results of the study showed no significant differences between groups in locus of control or anger. Out of the 72 subjects in the final analysis, 64 (89%) believed they had PMS, and only 8 (or 11%) believed they did not. Self-diagnosis was not always correct; 16 (22%) of the women who believed they had PMS did not meet the DSM-IV criteria for the disorder. The DSM-IV criteria may need further refinement and validation.

Adult↗

PubMedDate not supplied