Search PubMed⌕ Search

Biomedical subjects

H Smith

Publications and source records attributed to H Smith.

At least 865 records · Page 48Linked to original sources

Separation of antigens by immunological specificity: Use of cellulose-linked antibodies as immunosorbents.

1. Immunosorbents were prepared by coupling activated aminocellulose with the gamma-globulin concentrates of antisera prepared against ovalbumin and human serum albumin. 2. The immunosorbents were low in solubility, but high in capacity for homologous antigens. 3. The high specificity of these immunosorbents was demonstrated by their use in fractionating various mixtures of fluorescent ovalbumin, (131)I-labelled human serum albumin, lysozyme and ribonuclease.

Journal Article↗

Separation of antigens by immunological specificity: Use of disulphide-linked antibodies as immunosorbents.

1. gamma-Globulin concentrates of antisera prepared against ovalbumin and human serum albumin were thiolated and cross-linked to form insoluble polymers. 2. These immunosorbents were of low solubility and of high capacity for homologous antigen. 3. The high specificity of these immunosorbents was demonstrated by fractionation of various binary mixtures of fluorescent ovalbumin, (131)I-labelled human serum albumin, lysozyme and ribonuclease.

Journal Article↗

Serological screening test for infectious mononucleosis using papain-treated sheep erythrocytes.

A screening test for infectious mononucleosis is described, based on the fact that antibodies against sheep red cells remaining after absorption of the serum by papain-treated sheep red cells appear to be specific for the disease. The test appears to be more useful in diagnosis than classical absorption techniques and has the advantage of being specific while maintaining a high degree of sensitivity.

Humans↗