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Biomedical subjects

H Silver

Publications and source records attributed to H Silver.

At least 73 records · Page 4Linked to original sources
PubMed1986

Physical complaints correlate better with depression than do dexamethasone suppression test results.

DST responses of 67 Israeli inpatients, a group heterogeneous in ethnic background, were examined. Overall, 56% of depressed patients and 34% of patients with diagnoses other than depression were DST nonsuppressors. Ethnic background did not significantly influence the DST response. Scores on the Carroll Rating Scale for Depression (CRS) and the Physical Complaints List (PCL) did not correlate significantly with DST response. PCL scores correlated significantly with the diagnosis of depression. The data support the view that the DST has limited utility as a biologic marker of depression, but that an analysis of physical complaints using the PCL may be useful in the differential diagnosis of depression in some cultures.

Adult↗
PubMed1983

Treatment of thrombotic thrombocytopenic purpura. Evaluation of plasma exchange and review of the literature.

This report examines the results of treatment in 21 patients with thrombotic thrombocytopenic purpura (TTP) diagnosed over a 4-year time period (1976-1980) with a review of the possible role of each form of therapy in relationship to the various proposed pathogenic mechanisms. There was a 76.2% (16/21) overall survival with no significant difference in initial hematologic values in patients not surviving. Patients not surviving did not achieve a sustained platelet count greater than 150,000/microliters at any time during their clinical course. 16 patients received steroids, antiplatelet agents and plasma exchange, with a total volume exchanged ranging from 20.8 to 1,455 ml/kg, as part of their treatment protocol. In this group of patients there was an 81.2% (13/16) survival, with 4 patients receiving additional therapy including splenectomy and/or vincristine. There was no correlation between the intensity of plasma exchange and the time to hematologic recovery. It is apparent that controlled clinical trials are necessary to better define the effectiveness of the present forms of therapy.

Adult↗
PubMed1982

Reduction of capsular contracture with two-stage augmentation mammaplasty and pulsed electromagnetic energy (Diapulse therapy).

A two-stage augmentation mammaplasty was performed on 231 patients (462 implants) over a period of 3 years. Two hundred and sixteen of the cavities (47 percent) were found to have hematomas at the time of the second surgical stage. After removal of the hematomas and completion of the second stage, only 41 breast (9 percent) developed capsular contracture. Treatment of the 41 with Diapulse therapy, massage, and closed capsulotomy completely eliminated all capsular contracture. The period of observation has ranged from 3 months to 2 1/2 years.

Breast↗
PubMed1980

Anesthesia for outpatient head and neck aesthetic surgery.

An approach to outpatient anesthesia using drugs that have reversible or very short-acting effects is described, along with a method of monitoring patients using pulse rate to assess tranquility. Preoperatively, the patient is given 1 mg of lorazepam the evening before surgery and sublingual lorazepam 1 mg combined with hydroxyzine 50 mg intramuscularly one hour before surgery. Before infiltration of local anesthesia, intravenous diazepam in 2.5 mg increments is given if needed, followed by a mixture of meperidine and pentazocine intravenously in exactly a 10:1 ratio. If hypnosis is needed, methohexital can be administered using a 0.2% drip by infusion pump. If respiratory depression is seen, intravenous naloxone, 0.2 to 0.4 mg, can be given to reverse any residual effects of meperidine and pentazocine, or, if large doses of intravenous diazepam have been used in a very agitated patient, one can administer physostigmine 1 to 2 mg.

Ambulatory Surgical Procedures↗
PubMed1980

HBe-Antigen in the course and prognosis of hepatitis B infection: a prospective study.

The prognostic significance of the HBe-antigen (HBeAg) in the course and outcome of type B hepatitis was studied prospectively in 71 susceptible oncology patients. The patients had been exposed to tumor cell vaccines inadvertently contaminated with hepatitis B surface antigen (HBsAg)-containing plasma. Forty-five patients (63%) were infected. These 45 showed three types of acute seroresponse: HBsAg and HBeAg, 28 patients (62%); HBsAg alone, 8 patients (18%); and a primary antibody to HBsAg (anti-HBs) response, 9 patients (20%). There was no significant difference in acute course and outcome between the two HBs-antigenemic groups. All primary anti-HBs responders had asymptomatic infections. Seventeen patients receiving chemotherapy during the period of hepatitis B exposure were significantly more prone to symptomatic infection with acute HBs-antigenemia, and 2 of these patients developed chronic active hepatitis. The HBeAg is common early in acute hepatitis B among solid tumor patients and at this stage in disease has no prognostic significance independent of HBsAg.

Adult↗