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Biomedical subjects

H Siebke

Publications and source records attributed to H Siebke.

4 recordsLinked to original sources

Thoracic injuries.

Establishment of adequate ventilation takes the absolute precedence over all other therapeutic measures. Chest trauma has, therefore, the highest priority in a patient with multiple injuries. Bleeding may also be a decisive component. Emergency treatment aims at reestablishing normal physiological functions. Concurrently, diagnostic measures are taken to assess the underlying pathoanatomical changes. Treatment of chest injuries is a team effort of surgical and anaesthetic staff.

Bronchi↗

Reactions to intravenous injections of diazepam.

Local reactions during and after i.v. injection of two different formulations of diazepam were studied. Two-thirds of the patients felt pain during the injection. Verfied or probable thrombophlebitis occurred with increasing frequency following operation, indicating a late onset. One month after discharge, 29% of those who had received diazepam in glycoferol-alcohol-benzoic acid complained of tender injection sites, compared with only 10% of the patients who received diazepam in cremophor EL. The difference is significant, indicating an influence of the solvent system.

Diazepam↗

Survival after 40 minutes; submersion without cerebral sequeae.

Cardiopulmonary resuscitation and rewarming were successful in a 5-year-old boy who had been submerged for 40 minutes in ice-cold fresh water. Severe metabolic acidosis was corrected by intravenous infusion of sodium bicarbonate solution before spontaneous circulation could be re-established. Fulminant pulmonary oedema developed after re-establishment of spontaneous circulation. This was efficiently reversed by positive-end-expiratory-pressure ventilation. During 2 days of treatment of a respiratory the patient gradually regained consciousness; the endotracheal tube was then removed and the patient immediately started talking intelligently. The patient went through a period of slow cerebration and motor dysfunction but recovered rapidly, and on examination 13 months after the accident all findings were normal.

Acidosis↗