Search PubMed⌕ Search

Biomedical subjects

H Shen

Publications and source records attributed to H Shen.

At least 343 records · Page 19Linked to original sources
PubMed1990

[Pharyngeal area measured by acoustic reflection technique while breathing room-air].

Although there have been many reports on the airway area measured by breathing 80% He-20% O2 (He-O2) using the acoustic reflection technique (ART), there have been no reports on that by breathing room-air (Air) because of the lack of accuracy in evaluating the trachea. When measuring with He-O2, accidental introduction of Air into the airway makes the measurement inaccurate. Moreover, it is a time-consuming method and is hardly applicable to dyspneic patients. Therefore, we tried to assess whether the airway area, especially the upper airway, can be measured while breathing Air. In order to compare the areas determined by the two methods, area-distance functions from the pharynx to the trachea were arbitrarily divided into 9 divisions at interval of 2.8 cm. Each of these divisions was respectively compared. We took averages of the pharyngeal, tracheal areas in 8 normal subjects. We found no significant difference between the oropharyngeal area measured by breathing Air and that measured by breathing He-O2, and found a significant correlation between them. There was a significant correlation between the hypopharyngeal areas when using the two methods. The average tracheal area by breathing Air is 4.96 +/- 0.50 cm2, which is 40% above that when measured using He-O2 (3.55 +/- 0.32 cm2). In contrast, the average pharyngeal area when breathing Air is 4.13 +/- 0.93 cm2, which overestimates that by breathing He-O2, namely 3.54 %/- 0.84 cm2 by only 17%. In conclusion, it is possible and useful to estimate the pharyngeal area by breathing Air.

Acoustics↗
PubMed1989

[Ultrastructural observation on the body wall of Pagumogonimus skrjabini].

This paper deals with the ultrastructure of the body wall of adult Pagumogonimus skrjabini by transmission electron microscopy. Infected crabs were collected from Siyen, Hubei Province, and adult worms were obtained from the lungs of experimentally infected dogs 90 days post-infection. The normal structure of body wall of the P. skrjabini is composed of tegument, tegument cell, muscle muscle cell and protoplasmic tubules, all of which form together syncytium. The tegument contains external plasma membrane, tegument matrix and basal plasma membrane. The cell coat in fine granules is distributed over the whole external plasma membrane surface. The tegument matrix contains various secretory bodies, vesicles and mitochondria. The tegument cell is irregular in shape. Golgi complex, ribosome, autolysosome are seen in the cytoplasm. There are two layers of muscle, the external circular muscle and the inner longitudinal muscle layers. The nucleus of immature muscle cell has many heterochromatins, while the nucleus of mature muscle cell is large and round in shape. Mitochondria and glycogen granules are transmitted from muscle cell proper to the muscle by protoplasmic tubules (Figs. 1 approximately 7).

Animals↗
PubMed1989

[The finite element analysis of the bicuspid and molar of mandible].

Recently, the finite element method has been adopted in the study of tooth structure as well as the stress distribution of dental prosthesis. In order to understand the loading state of the supporting tissues and the stress distribution of the teeth in various shapes under the pressure of loading, the author of this essay has applied the two-dimensional finite element method to the study of the stress distribution of the periodontal supporting tissues at the time when the second bicuspid and the second molar are vertically and obliquely loaded. Finally, the results of the quantitative analysis are obtained and a curve of the stress distribution of the teeth is also drawn up. The conclusion is as follows: 1. When the vertical loading is applied to the occlusal surface of the bicuspid and molar, the stress distribution of periodontal supporting tissues is uniform. 2. The stress concentration is on the marginal ridge and thedistal apex of bicuspid under the oblique loading. 3. When the oblique loading is applied to the occlusal surface of the molar, the stress concentration is only on the marginal ridge, and it is small.

Alveolar Process↗
PubMed1986

Analysis of surface deposits on intrauterine contraceptive devices.

Surface deposits on stainless steel contraceptive devices removed from the uterus after varying periods of insertion were examined and analyzed by means of scanning electron microscopy (SEM), X-ray energy dispersive analysis (XEDA), Augar electron spectroscopy (AES), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and atomic absorption spectrophotometry for microquantitative analysis. The data obtained were compared with the data for copper-bearing IUDs (TCu200) obtained by the same method. The wire coils of stainless steel IUDs which had been in situ for 5 years showed no obvious changes, but copper wire coils showed varying degrees of erosion after the same period of time. Analysis clearly showed that the wire coils of both types of IUD were encrusted with deposits. Deposition began earlier on copper-bearing IUDs than on stainless steel IUDs (27 days and 3 months after insertion, respectively). This process began earlier than has previously been reported in the literature. The amount of deposit increased with duration of insertion, but there were large individual variations. The microanalysis showed that the principal component of the deposit on both types of IUD was calcium, which was present in the crystal form of calcium carbonate. The substances attaching to the crystals were similar to the nitrogenous organic compounds. We suggest that the mechanism regulating the deposited formation may be similar to that of calculus. The influence of these deposits on complications relating to IUD insertion, such as uterine bleeding and accidental pregnancy, is briefly discussed in this article. The subject should be studied in greater detail.

Calcium Carbonate↗
PubMed1986

A randomized comparative clinical evaluation of the Steel Ring, the VCu200 and the TCu220c IUDs.

A randomized comparative clinical study of the Steel Ring, VCu200 and TCu220c IUDs was carried out in Beijing. Six-hundred subjects were recruited and each group of 200 was inserted with one of the three devices. The TCu220c and the VCu200 had statistically significantly lower pregnancy and expulsion rates at one and two years of use than the Steel Ring. However, the Steel Ring consistently had the lowest rate of removal for pain and/or bleeding. At two years, the early differences of use-related discontinuation and continuation between the higher rates of the Steel Ring and the lower rates of the VCu200 and TCu220c were significantly reduced. There were no statistically significant differences of net event rates between VCu200 and TCu220c.

Adult↗
PubMed1986

[Photodynamic therapy (PDT) of bladder cancer in the rat].

PDT of rat bladder cancer, induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) was studied. All animals were divided at random into three groups. Group 2 and 3 were treated by hematoporphyrin derivative (HPD)-laser PDT while group 1, without treatment, served as control. The results showed that the malignant lesions could be selectively and obviously destroyed, if the whole tumor area were sufficiently exposed to the laser irradiation. However, the normal bladder epithelium and muscle layer showed no histologic change. Similar reactions were found in papilloma of bladder which was considered as precancerous lesion. Thus, PDT may be beneficial to cancer prevention. Its role in prevention and treatment of bladder cancer should be further studied experimentally and clinically.

Animals↗
PubMed1985

The biological effects of photodynamic therapy on normal skin in mice--I. A light microscopic study.

A light microscopic investigation of the biological effects of photodynamic therapy using hematoporphyrin derivative and red light irradiation has been carried out. HpD alone, even used at a dose of 50 mg/kg, did not cause histologically discernible changes. The irradiation alone used in this experiment caused only slight or moderate dilatation and congestion of blood vessels, which disappeared completely within several hours after light exposure. In the PDT treated mouse ears severe degeneration and necrosis of skin tissue occurred within 1-2 days. The importance of adequate drug and light doses and proper interval chosen for obtaining best therapeutic effects and protection of surrounding normal tissues was pointed out. The possible mechanism of the PDT action in vivo was briefly discussed.

Animals↗
PubMed1985

The biological effects of photodynamic therapy on normal skin in mice--II. An electron microscopic study.

In the present study it has been demonstrated that the ultrastructural changes in mouse ear skin after PDT action occurred much more distinct and earlier than those observed in the histological study. Various types of cells in the skin respond to the photodynamic action differently. The endothelial cells, fibroblasts and nerve fibers are most sensitive. In contrast, the keratinocytes and chondrocytes often remain rather well preserved after PDT treatment. The possible mechanism of PDT action was briefly discussed.

Animals↗