[TNM--current status. 1. Clinical significance and current status].
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Biomedical subjects
Publications and source records attributed to H Seib.
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It is demonstrated the unusual case of a 14-year-old boy, dying suddenly after physical stress with myocardial infarction. Autoptically it was found a coronary artery anomaly of the "malign type" and in addition a significant narrowing of the left main coronary artery. There are presented until now in the literature 17 cases of sudden death in young patients (up to 22 years) in connection with the "malign coronary artery anomaly origin" of both coronary arteries from the right coronary sinus and course of the left coronary artery between the truncus of pulmonary artery and aorta. All 17 cases of sudden death were male. No explanation of the predominance of the male sex is known. Always physical stress preceded the fatal event. Obviously all other abnormalities of coronary artery origin of the aorta and course--except the Bland-White-Garland Syndrome--are of minor clinical importance. In the course of life all coronary vessel anomalies can be accompanied by atherosclerotic processes, followed by clinical symptoms of coronary artery disease. The additional speciality of the demonstrated case is the significant stenosis (75%) in the abnormal course of the main coronary artery. Practical consequence of the presented case is: Even in young patients and children one must be aware of the possibility of a myocardial infarction with coronary artery abnormality if clinical symptoms are present. There may be diagnostic (coronary arteriography) and therapeutic (coronary artery surgery) consequences, if the patient survives the life-threatening event.
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Elderly motorists lose a significant amount of their mental(-somatic) and sensomotor capabilities. No data is available on the percentage of elderly motorists involved in car accidents. Their accident risk, however, is not above average because that decrease is outweighed by increased experience and a more thoughtful manner of driving. The percentage of elderly, especially female pedestrians killed by autos is very high. This is mainly due to age-specific mortality and to the high proportion of aged people, especially women, within the population. Our jurisdiction concerning responsibilities requires elderly people to become aware of any deficiencies and to take them into account. The administrative courts are very reserved in withdrawing driving licenses because of age-caused deficiencies. The mere fact that a driver is very old does not suffice; it even does not justify seeking a psychomedical opinion. In this paper it is argued that actions provided for by the law and regulations asking for a periodical check-up of sensomotor and mental capabilities of the elderly driver are disproportionate. Introducing an "eye-certificate" for all motorists as suggested by the German Ophthalmological Society, however, is considered useful and appropriate since deficiencies of vision have been discovered for all age groups.