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Biomedical subjects

H Schwartz

Publications and source records attributed to H Schwartz.

At least 127 records · Page 7Linked to original sources
PubMed1977

Evidence from UV transcription mapping in HeLa cells that heterogeneous nuclear RNA is the messenger RNA precursor.

The effects of UV irradiation on the incorporation of [3H]uridine in HeLa (human) cell mRNA, rRNA, heterogeneous nuclear RNA (hnRNA) and early mRNA from adenovirus type 2 have been compared. The UV target size of cell mRNA is at least 3 times larger than the average size of the mRNA itself and larger than the adenovirus-2 early mRNA, which is known to derive from transcription units of about 1.5-5.0 kilobases. The UV target size of hnRNA, in contrast, is about the same as its size determined by sedimentation and overlaps with the target size of mRNA. It is concluded that most mRNA derives from a higher molecular weight hnRNA molecule.

Adenoviridae↗
PubMed1977

The effect of triiodothyronine on 2-deoxy-D-(1-3H)glucose uptake in cultured chick embryo heart cells.

The uptake of 2-deoxy-D-[1-3H]glucose ([1-3H]DOG)by cultured chick embryo heart cells was stimulated by exposure to triiodothyronine (T3). The concentration of free T3 for half maximal stimulation of [1-3H]DOG uptake was 8.7 x 10(-10)M. Nuclear binding studies revealed that the Kd for T3 was 4.2 x 10(-10)M. The molar potencies of other thyroactive compounds in stimulating [1-3H]DOG uptake, relative to L-T3, were: 500% for 3'-isopropyl-3,5-diiodo-L-thyronine, 20% for L-thyroxine (T4), 17% for D-T3, 2.2% for D-T4, 0.6% for 3,5-diiodo-L-thyronine and less than 0.1% for 3',5',3-triiodo-L-thyronine and L-thyronine. These data suggest that cultured chick embryo heart cells may serve in the study of the mode of action of thyroid hormones.

Animals↗
PubMed1975

Wenckebach phenomenon within the atria.

A patient with a history of fainting and a bifacicular block (CRBBB plus LPH) was analyzed by His Bundle electrograms. During atrial pacing at a rate of 138/min, a Wenckebach type of block occurred within the atrium or at the electode-atrium junction, or both. The sinus intra-atrial conduction time (P-A inverval) was normal. During atrial pacing (pacing rate of 138 to 148/min), St-A interval progressively lengthened and ultimately a second degree Wenckebach type of block was obtained. The surface electrocardiogram (ECG) was normal and only electrical pacing brought on the intra-atrial conduction defect. Simultaneous with this atrial block, a second degree (Mobitz II) block developed.

Aged↗
PubMed1975

Chicken soup rebound and relapse of pneumonia: report of a case.

A case is reported in which a previously healthy individual, having received an inadequate course of chicken soup in treatment of mild pneumococcal pneumonia, experienced a severe relapse, refractory to all medical treatment and eventually requiring thoracotomy. The pharmacology of chicken soup is reviewed and the dangers of abrupt termination of therapy are stressed.

Clinical Trials as Topic↗