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Biomedical subjects

H Schwartz

Publications and source records attributed to H Schwartz.

At least 91 records · Page 5Linked to original sources

Unusual echocardiographic findings in primary pulmonary hypertension.

A patient with primary pulmonary hypertension showed unusual echocardiographic findings. These included echoes arising from an intracavitary right ventricular muscle band mimicking a divided interventricular septum. The hemodynamic study excluded subvalvular right ventricular obstruction. Severe right ventricular hypertrophy was also present. Both findings were probably related and may possibly be found in similar cases with severe right ventricular hypertrophy, especially due to primary pulmonary hypertension. The right ventricular muscle band possibly represented hypertrophied moderator band.

Adult↗

Acute alterations of behavioral rhythms through classical conditioning.

A classical conditioning method was used to alter in acute fashion a discrete portion of the activity rhythm of squirrel monkeys living in social groups. Time of day was considered the unconditioned stimulus, while a previously neutral flashing light was used as the conditioned stimulus. When the CS was associated with an active period, its subsequent presentation during a quiet time of day resulted in significant increases in activity in conditioned subjects. This demonstration of the conditionability of daily activity patterns has important implications in both clinical and experimental settings.

Activity Cycles↗

Anti-inflammatory action of dexamethasone in vitrectomy infusion fluid.

Vitrectomy and lensectomy were performed in rabbits with infusion fluid containing dexamethasone. No ocular toxicity was observed in eyes that received dexamethasone up to a concentration of 400 micrograms/ml. Utilizing sensitive radioimmunoassay techniques after surgery, we observed significant reduction in ocular albumin levels in eyes treated with dexamethasone when compared with control eyes in which dexamethasone was not used. However, there was no significant difference in immunoglobulin levels between eyes from both groups.

Albumins↗

Iris angiography and aqueous photofluorometry in normal subjects.

Iris angiography and photofluorometry of the aqueous were performed on 44 normal subjects equally distributed between 15 and 65 years of age. Hemoglobin AIc determinations were performed in 20 of these persons. Leakage from the pupillary margin was present in 20% of the eyes studied. In all cases of leakage, the dye faded quickly after the initial peak concentration. No leakage was observed from radial iris vessels. Photofluorometric readings of the aqueous 60 minutes after injection increased significantly with age. Hemoglobin AIc measurements were observed to correlate significantly with aqueous fluorescein concentration. Both these observations may reflect an altered permeability of biologic membranes associated with aging.

Adolescent↗

Lacrimal gland adenoid cystic carcinoma: intracranial and extracranial en bloc resection.

Adenoid cystic carcinoma of the lacrimal gland is a rare tumor, although it is the malignancy most frequently arising in the gland. Treatment has been unsuccessful generally, with a 15-year survival of less than 20 percent. Our experience with this tumor in a 61-year-old woman has led to a proposal for therapeutic management based on awareness of the lesion's natural history, an understanding of regional anatomy, and familiarity with therapies reported in the literature. The feasibility of adequate tumor ablation is determined from preoperative evaluation, including CT scan, initial exploratory craniotomy, and frozen-section examination of the cranial nerves transversing the orbit. Once resectability is confirmed, "curative" intracranial and extracranial en bloc resection is performed, including the tumor, the lacrimal gland, and all contiguous structures. The defect is immediately resurfaced with and "ice cream cone" forehead flap in anticipation of adjuvant radiotherapy. An orbital prosthesis is fitted as soon as the radiation reaction subsides, and a postablative CT scan is obtained as the baseline for follow-up. It remains to be seen whether this application of the technology of CT scanning and the techniques of craniofacial surgery will improve the prognosis for adenoid cystic carcinoma arising in the lacrimal gland.

Carcinoma, Adenoid Cystic↗