Search PubMed⌕ Search

Biomedical subjects

H Schnieden

Publications and source records attributed to H Schnieden.

50 records · Page 3Linked to original sources
PubMed1971

Spasmolytic effects of cadmium and zinc ions upon the guinea-pig isolated ileum preparation.

1. An investigation has been made of the effects of cadmium and zinc ions upon the contractile response of the guinea-pig isolated ileum to methacholine, histamine, potassium ion and a.c. field stimulation. The metal ions depress the response to all of these agents.2. Radioisotope studies showed that cadmium and zinc ions have very much larger apparent volumes of distribution than sorbitol, both within whole ileum and within strips of the longitudinal smooth muscle layer. The results of these studies were indicative of surface binding and/or intracellular accumulation of these ions.3. It is suggested that cadmium and zinc ions directly depress smooth muscle contractility in a non-specific manner. This action may result from their binding to or accumulation within the muscle cells.

Animals↗
PubMed1969

Investigation of the spasmogenic effect of manganese on the guineapig isolated ileum preparation.

1. The mechanism of the manganese-induced spasm of the guinea-pig ileum was investigated using agents known to modify nerve function. The spasm was reduced by cooling, tetrodotoxin, procaine, Botulinus toxin (Type A), hyoscine and pempidine. It was potentiated by mipafox.2. In the presence of manganese, the release of acetylcholine from the ileum was greatly increased.3. Tetrodotoxin prevented the manganese-induced increase in acetylcholine output from the ileum but had no significant effect on the spontaneous acetylcholine output.4. It is suggested that the manganese-induced spasm of the ileum results from an action on intramural cholinergic nerves.

Acetylcholine↗
PubMedDate not supplied

Variations in sperm count in oligozoospermic or asthenozoospermic patients.

Using a Coulter Counter, sperm density and total sperm population per ejaculate has been measured repeatedly in a series of oligozoospermic and asthenozoospermic patients. Marked variations in these parameters were found with repeated sampling from the same patient. The implications of such findings are discussed.

Cell Count↗